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The map label for this gene is hsaB [H]

Identifier: 148661747

GI number: 148661747

Start: 2201993

End: 2202508

Strand: Direct

Name: hsaB [H]

Synonym: MRA_1949

Alternate gene names: 148661747

Gene position: 2201993-2202508 (Clockwise)

Preceding gene: 148661746

Following gene: 148661748

Centisome position: 49.82

GC content: 67.44

Gene sequence:

>516_bases
GTGAGCTGCACCTTCGACATGGTCCCGGAGACCGTCGATCATCTCGACGAGGTCGGGCTGCGGCGGGTCTTCGGCTGCTT
TCCGTGCGGCGTGATCGCCGTCTGCGCGATGGTCGACGACCAGCCGGTCGGCATGGCGGCCAGCTCGTTCACGTCGGTTT
CAGTTGACCCGCCGCTGGTATCGATCTGTGTGCAGAACTGTTCGACGACGTGGCCGAAGTTGCGCGACCGCCCACGGCTC
GGTGTGAGCGTGCTCGCCGAGGGGCACGACGCGGCCTGTATGAGCCTGTCGCGCAAGGAAGGTAACCGGTTCGCCGGGGT
GTTCTGGAGCGAATTGTCCAGCGGGGGTGTGGTGATCGCCGGGGCCGGCGCCTGGCTGGATTGCCGCCCGTACGCGGAGA
TCCCGGCGGGGGATCACCTGATCGCCCTGCTGGAGATCTGCGCGGTGCGCGCCGATCCCGAGACACCGCCGCTGGTGTTT
CACGGTAGCCGGTTCCGCCGGTTGGAGTCTCGATGA

Upstream 100 bases:

>100_bases
GCGGCACCCACATGATCGCCGACGTCGGACACTGGATCCAGCAGGAAGCGCCCGAAGAGACCAACCGGCTGTTGCTCGAC
TTCCTAGGCGGGCTGCGGCC

Downstream 100 bases:

>100_bases
AGACGACCGATGTGCGGGTACGTCGTGCGATCACGGCGATGGCGGGCGGTCACGCCGTGGTCCTGACCGGCGACCCCAAT
GGCGATGGCTATCTCGTCTT

Product: putative dimerase

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSCTFDMVPETVDHLDEVGLRRVFGCFPCGVIAVCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTTWPKLRDRPRL
GVSVLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAEIPAGDHLIALLEICAVRADPETPPLVF
HGSRFRRLESR

Sequences:

>Translated_171_residues
MSCTFDMVPETVDHLDEVGLRRVFGCFPCGVIAVCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTTWPKLRDRPRL
GVSVLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAEIPAGDHLIALLEICAVRADPETPPLVF
HGSRFRRLESR
>Mature_170_residues
SCTFDMVPETVDHLDEVGLRRVFGCFPCGVIAVCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTTWPKLRDRPRLG
VSVLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAEIPAGDHLIALLEICAVRADPETPPLVFH
GSRFRRLESR

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 18410; Mature: 18279

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCTFDMVPETVDHLDEVGLRRVFGCFPCGVIAVCAMVDDQPVGMAASSFTSVSVDPPLV
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHHH
SICVQNCSTTWPKLRDRPRLGVSVLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIA
HHHHHHCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEHHHHCCCCCEEEE
GAGAWLDCRPYAEIPAGDHLIALLEICAVRADPETPPLVFHGSRFRRLESR
ECCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECHHHHHCCCC
>Mature Secondary Structure 
SCTFDMVPETVDHLDEVGLRRVFGCFPCGVIAVCAMVDDQPVGMAASSFTSVSVDPPLV
CCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHHH
SICVQNCSTTWPKLRDRPRLGVSVLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIA
HHHHHHCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEHHHHCCCCCEEEE
GAGAWLDCRPYAEIPAGDHLIALLEICAVRADPETPPLVFHGSRFRRLESR
ECCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA