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The map label for this gene is lppD [C]

Identifier: 148661707

GI number: 148661707

Start: 2155146

End: 2156177

Strand: Reverse

Name: lppD [C]

Synonym: MRA_1910

Alternate gene names: 148661707

Gene position: 2156177-2155146 (Counterclockwise)

Preceding gene: 148661708

Following gene: 148661705

Centisome position: 48.78

GC content: 70.35

Gene sequence:

>1032_bases
ATGTCCCGGGCTGCCGGGTTGCCCCGGTTGTCCTGGTTTGCCGGGCTGACCTGGTTCGCCGGGGGTTCCACCGGGGCCGG
GTGCGCCGCCCACCCCGCCCTGGCCGGGTTGACCGCCGGGGCCCGCTGCCCCGCCTATGCCGCCATCTCCGCCTCTACCG
CCCGCCCCGCCGCGACCGCCGGCACCACCCCGGCCACCGGCGCCTCCGGCTCCGCCCGGCCCACCGACGCCGCGGGCATG
GCTGACCTCGCCCGGCCCGGCGTCGTCGCCACTCATGCTGTTCGCACCCTCGGTACAACTGGATCACGAGCCATCGGTCT
GTGTCCTTGCCAGCCGCTTGATTGTCCTCGTTCACCTCAAGCTACCCTGAATCTGGGCTCGATGGGCCGGAGTCTCGATG
GGCCGCAGTGGCGCCGGGCGAGGGTTCGATTGTGTGGGCGATGGTGGCGACGGTCCAACACAACAAGGGGTGCATCACCG
CGGCCGCCGAGTACTTGCAGGGGGGACAATGTGTCGATGATCGAGTTGGAGGTACATCAGGCCGACGTGACCAAGCTCGA
GCTCGACGCCATCACCAATGCGGCGAACACCCGACTGCGGCATGCCGGTGGTGTCGCTGCGGCCATCGCCCGCGCCGGCG
GCCCCGAGCTGCAGCGCGAGTCCACCGAGAAGGCGCCGATTGGGCTTGGGGAAGCGGTCGAGACCACGGCCGGTGACATG
CCGGCGCGCTACGTGATCCACGCGGCGACGATGGAGCTAGGAGGTCCGACCTCGGGCGAGATCATCACCGCAGCCACCGC
TGCTACCCTGCGGAAAGCCGACGAGCTCGGTTGCCGCTCGCTGGCGCTGGTGGCTTTCGGCACGGGCGTGGGCGGCTTTC
CGCTCGACGACGCTGCGCGGCTGATGGTCGGCGCCGTCCGTCGGCACCGGCCGGGGTCGCTGCAAAGGGTGGTATTTGCG
GTCCATGGGGATGCGGCCGAGCGGGCGTTTAGCGCTGCTATTCAGGCCGGAGAAGATACCGCTCGACGGTAG

Upstream 100 bases:

>100_bases
GGCACCGGTTCGCCGAGCGTGGTGAGCAGGAACTCAAGGGCGTACCGGGCAGATGGCGGCTATGCGTGCTCATGCGCGAC
GACGCCACCCGCACGCGCTA

Downstream 100 bases:

>100_bases
CGACCTTCTGGGTCATCGCGTCGGTGACCCCGGGACGCCAGTCCACCTTGATCACCGCGCTGACTCGCGGTGCCCGAGCG
GCCACGGCCTCCACCGCGCG

Product: putative lipoprotein LppD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAISASTARPAATAGTTPATGASGSARPTDAAGM
ADLARPGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATLNLGSMGRSLDGPQWRRARVRLCGRWWRRSNTTRGASP
RPPSTCRGDNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLGEAVETTAGDM
PARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAFGTGVGGFPLDDAARLMVGAVRRHRPGSLQRVVFA
VHGDAAERAFSAAIQAGEDTARR

Sequences:

>Translated_343_residues
MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAISASTARPAATAGTTPATGASGSARPTDAAGM
ADLARPGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATLNLGSMGRSLDGPQWRRARVRLCGRWWRRSNTTRGASP
RPPSTCRGDNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLGEAVETTAGDM
PARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAFGTGVGGFPLDDAARLMVGAVRRHRPGSLQRVVFA
VHGDAAERAFSAAIQAGEDTARR
>Mature_342_residues
SRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAISASTARPAATAGTTPATGASGSARPTDAAGMA
DLARPGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATLNLGSMGRSLDGPQWRRARVRLCGRWWRRSNTTRGASPR
PPSTCRGDNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLGEAVETTAGDMP
ARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAFGTGVGGFPLDDAARLMVGAVRRHRPGSLQRVVFAV
HGDAAERAFSAAIQAGEDTARR

Specific function: Unknown

COG id: COG2110

COG function: function code R; Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Macro domain

Homologues:

Organism=Homo sapiens, GI154813199, Length=176, Percent_Identity=31.25, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13569840, Length=175, Percent_Identity=31.4285714285714, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI117968621, Length=150, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226371710, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226371706, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226371716, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226371714, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226371712, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226371718, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787283, Length=175, Percent_Identity=32.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538214, Length=163, Percent_Identity=31.9018404907975, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1899_MYCTU (O07733)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   H70517
- RefSeq:   NP_216415.1
- RefSeq:   NP_336407.1
- ProteinModelPortal:   O07733
- SMR:   O07733
- EnsemblBacteria:   EBMYCT00000001333
- EnsemblBacteria:   EBMYCT00000070414
- GeneID:   885138
- GeneID:   923280
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1950
- KEGG:   mtu:Rv1899c
- TIGR:   MT1950
- TubercuList:   Rv1899c
- GeneTree:   EBGT00050000018547
- HOGENOM:   HBG571024
- OMA:   RSPQATL
- ProtClustDB:   CLSK791470
- HAMAP:   MF_01205_B
- InterPro:   IPR002589
- InterPro:   IPR022942
- SMART:   SM00506

Pfam domain/function: PF01661 Macro

EC number: NA

Molecular weight: Translated: 35072; Mature: 34941

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS51154 MACRO; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAISASTARPAATA
CCCCCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
GTTPATGASGSARPTDAAGMADLARPGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQ
CCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCC
ATLNLGSMGRSLDGPQWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQ
CEEEHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEC
ADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLGEAVETTAGDM
CCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHCCCCC
PARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAFGTGVGGFPLDDAAR
CHHEEEEEEEHCCCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHH
LMVGAVRRHRPGSLQRVVFAVHGDAAERAFSAAIQAGEDTARR
HHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAISASTARPAATA
CCCCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
GTTPATGASGSARPTDAAGMADLARPGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQ
CCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCC
ATLNLGSMGRSLDGPQWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQ
CEEEHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEC
ADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLGEAVETTAGDM
CCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHCCCCC
PARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAFGTGVGGFPLDDAAR
CHHEEEEEEEHCCCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHH
LMVGAVRRHRPGSLQRVVFAVHGDAAERAFSAAIQAGEDTARR
HHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036