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The map label for this gene is yddA [C]

Identifier: 148661625

GI number: 148661625

Start: 2072741

End: 2074660

Strand: Reverse

Name: yddA [C]

Synonym: MRA_1831

Alternate gene names: 148661625

Gene position: 2074660-2072741 (Counterclockwise)

Preceding gene: 148661639

Following gene: 148661624

Centisome position: 46.94

GC content: 62.24

Gene sequence:

>1920_bases
TTGGGCCCGAAATTGTTTAAGCCGTCCATCGATTGGTCTAGAGCATTCCCGGATTCCGTGTATTGGGTCGGCAAAGCCTG
GACGATCAGTGCCATCTGTGTGCTCGCGATATTGGTTCTGCTCAGGTATTTGACGCCCTGGGGCCGGCAGTTCTGGCGGA
TCACCCGCGCATACTTCGTTGGCCCCAACAGCGTTCGCGTGTGGCTGATGCTCGGCGTGTTGTTGCTTTCGGTAGTGCTG
GCAGTGCGCCTGAATGTGCTATTCAGCTACCAAGGCAACGACATGTACACGGCCTTGCAGAAGGCCTTCGAGGGCATCGC
CTCTGGCGATGGCACGGTCAAACGCTCAGGCGTGCGAGGATTTTGGATGTCGATCGGGGTTTTCAGCGTGATGGCCGTGC
TGCACGTGACCCGGGTCATGGCCGACATCTACTTGACGCAGCGCTTCATCATCGCCTGGAGGGTCTGGCTAACCCACCAC
CTCACACAAGACTGGCTCGACGGCAGGGCCTACTACCGAGACCTGTTCATCGACGAAACGATCGACAACCCCGACCAGCG
CATTCAGCAAGACGTCGATATCTTCACCGCCGGGGCAGGCGGCACTCCGAATGCTCCCTCCAACGGGACGGCCAGCACGC
TGCTTTTCGGGGCCGTGCAGTCGATCATTTCGGTGATTTCTTTCACAGCGATCCTGTGGAATCTCTCGGGCACCCTGAAT
ATCTTCGGCGTGTCCATCCCGCGCGCAATGTTCTGGACCGTGCTGGTCTATGTGTTCGTGGCCACGGTCATCTCGTTCAT
CATCGGGCGGCCCCTGATCTGGCTCAGCTTCCGCAATGAAAAGCTCAATGCCGCTTTCCGTTACGCGCTGGTTCGGCTAC
GCGACGCCGCCGAGGCGGTGGGTTTCTACCGCGGCGAGCGGGTGGAAGGTACCCAGCTACAGCGGCGGTTCACGCCGGTG
ATCGACAATTACCGTCGCTACGTTCGGCGCAGCATCGCATTCAATGGATGGAATCTGTCGGTGAGCCAGACAATTGTTCC
GTTGCCGTGGGTCATCCAGGCGCCTCGATTATTCGCCGGGCAGATCGACTTCGGCGATGTCGGGCAGACGGCGACTTCCT
TCGGCAACATTCACGACTCGTTGTCGTTCTTCCGCAACAACTACGACGCGTTTGCGTCCTTCCGCGCAGCAATCATCCGA
TTGCATGGGCTGGTCGACGCCAACGAGAAAGGCCGCGCCCTGCCCGCGGTCCTGACCCGACCGAGCGACGACGAGTCCGT
CGAGCTCAACGACATCGAGGTGCGTACGCCTGCCGGCGATCGGTTGATCGACCCGCTCGATGTGCGGCTGGACCGCGGAG
GCTCGCTGGTGATCACCGGGCGTTCTGGGGCCGGCAAGACCACGCTGCTGCGCAGTCTGGCGGAACTGTGGCCCTACGCA
TCGGGGACCCTGCACCGGCCGGGCGGCGAGAACGAGACGATGTTCTTGTCGCAGTTGCCGTATGTGCCGCTGGGGACGCT
GCGTGACGTGGTGTGCTACCCCAACTCTGCGGCCGCCATCCCCGACGCCACCCTGCGGGACACGCTGACCAAGGTGGCGC
TGGCCCCACTGTGTGACCGGCTGGACGAGGAACGCGACTGGGCCAAGGTGCTCTCCCCCGGTGAGCAGCAACGTGTTGCC
TTTGCTCGCATCCTGCTCACCAAACCCAAGGCGGTCTTCCTCGACGAAAGTACCTCGGCGCTGGACACCGGGCTGGAGTT
TGCGCTCTACCAATTGCTGCGCAGCGAGCTGCCGGACTGCATCGTGATCAGCGTCAGCCATCGCCCCGCCCTCGAGCGGC
TGCACGAAAACCAGCTCGAACTACTCGGTGGCGGCCAATGGCGGCTGGCCCCAGTCGAGGCGGCGCCCGCCGAAGTGTAA

Upstream 100 bases:

>100_bases
GGTCTGGGCCGGGGCGGTGTCGGTGCTCATATCGGCAGCCTATCGACAACCTTCGGGTACCTTCGCCCGAAGGATTTCTG
TTTGTGAGGAGACGTCGACC

Downstream 100 bases:

>100_bases
GCCGGGACGAGCTTCCCAAATCGGCGTGGCCGCTTCCGTGATCGCGATACGCTGAATCCGTCGATCTCTGGGGAGTGACC
AGGCGATCGGTAGCGGCCCC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVL
AVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHH
LTQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLN
IFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPV
IDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIR
LHGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYA
SGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVA
FARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV

Sequences:

>Translated_639_residues
MGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVL
AVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHH
LTQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLN
IFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPV
IDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIR
LHGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYA
SGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVA
FARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV
>Mature_638_residues
GPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVLA
VRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHL
TQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLNI
FGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPVI
DNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRL
HGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYAS
GTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVAF
ARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV

Specific function: Unknown

COG id: COG4178

COG function: function code R; ABC-type uncharacterized transport system, permease and ATPase components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI4826958, Length=570, Percent_Identity=29.1228070175439, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI4506341, Length=532, Percent_Identity=26.5037593984962, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI9945308, Length=549, Percent_Identity=25.5009107468124, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI7262393, Length=220, Percent_Identity=32.2727272727273, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI9961250, Length=240, Percent_Identity=27.9166666666667, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4505771, Length=240, Percent_Identity=27.9166666666667, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI9961252, Length=240, Percent_Identity=27.9166666666667, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1787772, Length=551, Percent_Identity=28.4936479128857, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1787112, Length=246, Percent_Identity=27.2357723577236, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787113, Length=276, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787029, Length=174, Percent_Identity=31.6091954022989, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87081709, Length=181, Percent_Identity=30.939226519337, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532409, Length=532, Percent_Identity=27.2556390977444, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17532411, Length=525, Percent_Identity=25.7142857142857, Blast_Score=172, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17558960, Length=672, Percent_Identity=25.5952380952381, Blast_Score=162, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17564250, Length=492, Percent_Identity=27.2357723577236, Blast_Score=155, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI72000520, Length=469, Percent_Identity=27.0788912579957, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17542146, Length=540, Percent_Identity=24.2592592592593, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI72000518, Length=522, Percent_Identity=26.0536398467433, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71992285, Length=420, Percent_Identity=25, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17558664, Length=255, Percent_Identity=27.0588235294118, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551702, Length=173, Percent_Identity=28.9017341040462, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17551700, Length=173, Percent_Identity=28.9017341040462, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71996550, Length=354, Percent_Identity=24.5762711864407, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=175, Percent_Identity=29.7142857142857, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325110, Length=200, Percent_Identity=39.5, Blast_Score=117, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6323959, Length=441, Percent_Identity=26.3038548752834, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=269, Percent_Identity=26.7657992565056, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24643394, Length=526, Percent_Identity=26.0456273764259, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24638550, Length=554, Percent_Identity=23.6462093862816, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24638552, Length=554, Percent_Identity=23.6462093862816, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24638554, Length=554, Percent_Identity=23.6462093862816, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24638546, Length=554, Percent_Identity=23.6462093862816, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24638556, Length=554, Percent_Identity=23.6462093862816, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24638548, Length=554, Percent_Identity=23.6462093862816, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24638558, Length=554, Percent_Identity=23.6462093862816, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI45552341, Length=559, Percent_Identity=21.6457960644007, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45552359, Length=559, Percent_Identity=21.6457960644007, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550972, Length=559, Percent_Identity=21.6457960644007, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397593, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1819_MYCTU (Q50614)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   D70720
- RefSeq:   NP_216335.1
- RefSeq:   NP_336326.1
- ProteinModelPortal:   Q50614
- EnsemblBacteria:   EBMYCT00000002539
- EnsemblBacteria:   EBMYCT00000071694
- GeneID:   885539
- GeneID:   923763
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1867
- KEGG:   mtu:Rv1819c
- TIGR:   MT1867
- TubercuList:   Rv1819c
- GeneTree:   EBGT00050000015057
- HOGENOM:   HBG555665
- OMA:   QAFGQVQ
- ProtClustDB:   CLSK791411
- InterPro:   IPR010509
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR011527
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF06472 ABC_membrane_2; PF00005 ABC_tran; SSF90123 ABC_TM_1

EC number: NA

Molecular weight: Translated: 71318; Mature: 71187

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50929 ABC_TM1F; PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e8d7528)-; HASH(0x1ef33abc)-; HASH(0x1efafde0)-; HASH(0x1d658c74)-; HASH(0x1f019210)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFV
CCCCCCCCCCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEE
GPNSVRVWLMLGVLLLSVVLAVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCCCEECCCCCH
FWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHLTQDWLDGRAYYRDLFIDET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
IDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLN
CCCHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAV
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GFYRGERVEGTQLQRRFTPVIDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCEEECCCHHEECCCCEEC
QIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRLHGLVDANEKGRALPAVLTR
CCCCCCCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEC
PSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYA
CCCCCCEEECEEEEECCCCCCCCCCHHEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCC
SGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDR
CCCEECCCCCCCEEEHHCCCCCCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LDEERDWAKVLSPGEQQRVAFARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDC
HCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCE
IVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV
EEEEECCCHHHHHHHHCCHHHCCCCCEEEEECCCCCCCH
>Mature Secondary Structure 
GPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFV
CCCCCCCCCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEE
GPNSVRVWLMLGVLLLSVVLAVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCCCEECCCCCH
FWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHLTQDWLDGRAYYRDLFIDET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
IDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLN
CCCHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAV
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GFYRGERVEGTQLQRRFTPVIDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCEEECCCHHEECCCCEEC
QIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRLHGLVDANEKGRALPAVLTR
CCCCCCCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEC
PSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYA
CCCCCCEEECEEEEECCCCCCCCCCHHEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCC
SGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDR
CCCEECCCCCCCEEEHHCCCCCCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LDEERDWAKVLSPGEQQRVAFARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDC
HCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCE
IVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV
EEEEECCCHHHHHHHHCCHHHCCCCCEEEEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036