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The map label for this gene is eccD5

Identifier: 148661601

GI number: 148661601

Start: 2042172

End: 2043683

Strand: Direct

Name: eccD5

Synonym: MRA_1808

Alternate gene names: 148661601

Gene position: 2042172-2043683 (Clockwise)

Preceding gene: 148661600

Following gene: 148661602

Centisome position: 46.2

GC content: 64.35

Gene sequence:

>1512_bases
ATGACCGCAGTAGCTGACGCACCTCAGGCTGACATTGAGGGTGTGGCATCGCCCCAGGCTGTCGTCGTGGGCGTCATGGC
CGGCGAAGGCGTCCAGATCGGCGTCCTGCTGGATGCCAACGCCCCAGTTTCGGTGATGACCGACCCGCTGCTGAAAGTGG
TTAATAGTCGGCTCAGAGAGCTCGGTGAGGCTCCACTGGAAGCCACTGGACGCGGCCGATGGGCGCTGTGTCTGGTGGAC
GGCGCGCCGTTGCGTGCTACCCAGTCGCTGACCGAACAAGACGTCTATGACGGCGACCGGCTGTGGATTCGGTTCATCGC
AGACACCGAACGTCGCTCCCAAGTCATCGAACATATCTCCACCGCAGTCGCCTCGGATCTCAGCAAGCGGTTCGCCAGGA
TCGACCCGATCGTTGCTGTGCAGGTCGGGGCGTCGATGGTGGCGACCGGGGTTGTTCTTGCCACCGGGGTGCTCGGCTGG
TGGCGCTGGCATCACAACACCTGGTTGACCACCATCTACACCGCGGTGATTGGTGTGCTGGTGCTGGCGGTCGCCATGTT
GCTGTTGATGCGTGCCAAGACGGACGCGGATCGACGCGTCGCCGACATCATGCTGATGAGCGCGATCATGCCCGTGACGG
TGGCGGCGGCAGCGGCCCCGCCCGGCCCGGTGGGCTCCCCGCAGGCCGTGTTGGGCTTCGGAGTGCTGACCGTCGCTGCG
GCCCTGGCCCTGCGGTTCACCGGTCGCCGCCTGGGGATTTACACCACAATCGTCATCATCGGTGCGCTGACAATGCTTGC
AGCCTTGGCGCGGATGGTCGCGGCCACAAGCGCGGTGACGCTGTTGTCGTCCTTGTTGTTGATTTGCGTAGTGGCCTACC
ACGCGGCGCCGGCACTGTCTCGGCGGCTGGCCGGCATCCGACTGCCGGTGTTCCCGTCCGCCACCAGCCGGTGGGTCTTC
GAGGCTCGGCCCGACCTACCGACCACCGTGGTGGTGTCCGGTGGCAGCGCACCGGTCTTGGAAGGGCCGTCATCGGTGCG
TGATGTGCTGCTGCAAGCTGAGCGCGCTCGGTCGTTCTTGAGCGGCCTGCTAACGGGACTTGGCGTGATGGTGGTGGTGT
GCATGACATCGTTGTGCGACCCGCACACCGGGCAACGTTGGCTGCCGCTGATACTGGCCGGATTTACCTCGGGCTTCCTG
CTGTTGCGGGGCCGCTCCTACGTCGACCGTTGGCAGTCGATTACCCTGGCCGGAACTGCGGTGATCATCGCTGCTGCGGT
GTGTGTGCGGTACGCGCTGGAATTGTCCTCGCCGTTGGCTGTGTCCATTGTCGCCGCGATCCTGGTGCTGCTGCCGGCGG
CGGGCATGGCAGCTGCTGCACATGTGCCCCACACCATCTACAGTCCGCTATTCCGCAAGTTTGTGGAATGGATTGAATAC
CTCTGCCTGATGCCGATCTTCCCGCTGGCGTTGTGGTTGATGAACGTCTATGCAGCGATTCGGTACCGGTAG

Upstream 100 bases:

>100_bases
TCCCGGTGGGCTACCGCGCCTCGGTGCCTACACCGACGGAGCTCCCCGCGCCACTGAAGCCACGGTGTAACACGTTTGCC
ATGGCAGGGGGTACAGGACG

Downstream 100 bases:

>100_bases
CAGCAGGTCGTGGTGTGGTCGCGCGGGTACCGCGACCATTGCCGCAGTCTTGCTAGCTTCGGGCGCGCTGACCGGCCTTC
CGCCAGCGTATGCAATTTCG

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component D5; Type VII secretion system protein eccD5; T7SS protein eccD5

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MTAVADAPQADIEGVASPQAVVVGVMAGEGVQIGVLLDANAPVSVMTDPLLKVVNSRLRELGEAPLEATGRGRWALCLVD
GAPLRATQSLTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVASDLSKRFARIDPIVAVQVGASMVATGVVLATGVLGW
WRWHHNTWLTTIYTAVIGVLVLAVAMLLLMRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGSPQAVLGFGVLTVAA
ALALRFTGRRLGIYTTIVIIGALTMLAALARMVAATSAVTLLSSLLLICVVAYHAAPALSRRLAGIRLPVFPSATSRWVF
EARPDLPTTVVVSGGSAPVLEGPSSVRDVLLQAERARSFLSGLLTGLGVMVVVCMTSLCDPHTGQRWLPLILAGFTSGFL
LLRGRSYVDRWQSITLAGTAVIIAAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRKFVEWIEY
LCLMPIFPLALWLMNVYAAIRYR

Sequences:

>Translated_503_residues
MTAVADAPQADIEGVASPQAVVVGVMAGEGVQIGVLLDANAPVSVMTDPLLKVVNSRLRELGEAPLEATGRGRWALCLVD
GAPLRATQSLTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVASDLSKRFARIDPIVAVQVGASMVATGVVLATGVLGW
WRWHHNTWLTTIYTAVIGVLVLAVAMLLLMRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGSPQAVLGFGVLTVAA
ALALRFTGRRLGIYTTIVIIGALTMLAALARMVAATSAVTLLSSLLLICVVAYHAAPALSRRLAGIRLPVFPSATSRWVF
EARPDLPTTVVVSGGSAPVLEGPSSVRDVLLQAERARSFLSGLLTGLGVMVVVCMTSLCDPHTGQRWLPLILAGFTSGFL
LLRGRSYVDRWQSITLAGTAVIIAAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRKFVEWIEY
LCLMPIFPLALWLMNVYAAIRYR
>Mature_502_residues
TAVADAPQADIEGVASPQAVVVGVMAGEGVQIGVLLDANAPVSVMTDPLLKVVNSRLRELGEAPLEATGRGRWALCLVDG
APLRATQSLTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVASDLSKRFARIDPIVAVQVGASMVATGVVLATGVLGWW
RWHHNTWLTTIYTAVIGVLVLAVAMLLLMRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGSPQAVLGFGVLTVAAA
LALRFTGRRLGIYTTIVIIGALTMLAALARMVAATSAVTLLSSLLLICVVAYHAAPALSRRLAGIRLPVFPSATSRWVFE
ARPDLPTTVVVSGGSAPVLEGPSSVRDVLLQAERARSFLSGLLTGLGVMVVVCMTSLCDPHTGQRWLPLILAGFTSGFLL
LRGRSYVDRWQSITLAGTAVIIAAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRKFVEWIEYL
CLMPIFPLALWLMNVYAAIRYR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eccD/snm4 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECCD5_MYCTU (O53944)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842577
- PIR:   D70930
- RefSeq:   NP_216311.1
- RefSeq:   NP_336301.1
- ProteinModelPortal:   O53944
- EnsemblBacteria:   EBMYCT00000003978
- EnsemblBacteria:   EBMYCT00000070119
- GeneID:   885628
- GeneID:   923789
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1844
- KEGG:   mtu:Rv1795
- TIGR:   MT1844
- TubercuList:   Rv1795
- GeneTree:   EBGT00050000016341
- HOGENOM:   HBG569276
- OMA:   WIRFIPD
- ProtClustDB:   CLSK791398
- InterPro:   IPR006707
- TIGRFAMs:   TIGR02958

Pfam domain/function: PF04600 DUF571

EC number: NA

Molecular weight: Translated: 53436; Mature: 53305

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e2af0f4)-; HASH(0x1ef9d374)-; HASH(0x1ee1454c)-; HASH(0x1e8eefc0)-; HASH(0x1ecf174c)-; HASH(0x1ec8b278)-; HASH(0x1dc2e5e8)-; HASH(0x1e8ccdf8)-; HASH(0x1c544624)-; HASH(0x1d873d8c)-; HASH(0x1ee75b20)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVADAPQADIEGVASPQAVVVGVMAGEGVQIGVLLDANAPVSVMTDPLLKVVNSRLRE
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LGEAPLEATGRGRWALCLVDGAPLRATQSLTEQDVYDGDRLWIRFIADTERRSQVIEHIS
HCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
TAVASDLSKRFARIDPIVAVQVGASMVATGVVLATGVLGWWRWHHNTWLTTIYTAVIGVL
HHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VLAVAMLLLMRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGSPQAVLGFGVLTVAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ALALRFTGRRLGIYTTIVIIGALTMLAALARMVAATSAVTLLSSLLLICVVAYHAAPALS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLAGIRLPVFPSATSRWVFEARPDLPTTVVVSGGSAPVLEGPSSVRDVLLQAERARSFL
HHHCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
SGLLTGLGVMVVVCMTSLCDPHTGQRWLPLILAGFTSGFLLLRGRSYVDRWQSITLAGTA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHH
VIIAAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRKFVEWIEY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
LCLMPIFPLALWLMNVYAAIRYR
HHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TAVADAPQADIEGVASPQAVVVGVMAGEGVQIGVLLDANAPVSVMTDPLLKVVNSRLRE
CCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LGEAPLEATGRGRWALCLVDGAPLRATQSLTEQDVYDGDRLWIRFIADTERRSQVIEHIS
HCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
TAVASDLSKRFARIDPIVAVQVGASMVATGVVLATGVLGWWRWHHNTWLTTIYTAVIGVL
HHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VLAVAMLLLMRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGSPQAVLGFGVLTVAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ALALRFTGRRLGIYTTIVIIGALTMLAALARMVAATSAVTLLSSLLLICVVAYHAAPALS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLAGIRLPVFPSATSRWVFEARPDLPTTVVVSGGSAPVLEGPSSVRDVLLQAERARSFL
HHHCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
SGLLTGLGVMVVVCMTSLCDPHTGQRWLPLILAGFTSGFLLLRGRSYVDRWQSITLAGTA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHH
VIIAAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRKFVEWIEY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
LCLMPIFPLALWLMNVYAAIRYR
HHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036