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The map label for this gene is eccB5

Identifier: 148661590

GI number: 148661590

Start: 2027672

End: 2029192

Strand: Direct

Name: eccB5

Synonym: MRA_1797

Alternate gene names: 148661590

Gene position: 2027672-2029192 (Clockwise)

Preceding gene: 148661588

Following gene: 148661591

Centisome position: 45.88

GC content: 65.09

Gene sequence:

>1521_bases
GTGGCTGAAGAGAGCCGCGGGCAGCGGGGGTCGGGGTATGGCCTTGGGTTGTCCACGCGGACCCAGGTAACCGGTTATCA
GTTCCTGGCGCGTCGAACCGCAATGGCGTTGACACGCTGGCGTGTGCGTATGGAGATTGAGCCGGGTCGGCGGCAGACGT
TGGCGGTGGTGGCGTCGGTGTCGGCGGCGTTGGTGATCTGTCTGGGGGCGCTGTTGTGGTCGTTCATCAGCCCGTCCGGC
CAGTTGAATGAGTCGCCGATCATCGCAGACCGCGATTCCGGTGCGCTCTATGTCCGTGTCGGTGACAGGTTGTACCCGGC
GCTGAATTTGGCATCGGCACGGCTGATCACCGGGCGGCCGGACAACCCGCACCTGGTTCGGTCAAGCCAGATTGCCACCA
TGCCGCGCGGTCCGCTGGTGGGTATCCCGGGTGCGCCGTCATCGTTCTCGCCAAAGAGTCCACCCGCGTCGTCTTGGCTG
GTCTGCGACACGGTAGCGACCTCGTCAAGCATCGGGTCGCTGCAAGGCGTGACGGTGACGGTCATCGACGGGACCCCGGA
CCTTACCGGTCACCGGCAGATTTTGAGTGGATCGGACGCGGTAGTGCTGCGCTACGGCGGAGATGCGTGGGTCATCCGGG
AGGGGCGCCGGTCACGAATCGAGCCGACGAATCGAGCGGTGTTGTTGCCGCTGGGGTTGACGCCGGAGCAGGTTAGCCAG
GCGCGTCCGATGAGCCGGGCATTGTTCGACGCTTTGCCGGTCGGGCCCGAACTGTTGGTGCCGGAAGTGCCGAATGCGGG
TGGTCCTGCGACGTTCCCGGGCGCTCCCGGACCGATCGGGACGGTAATCGTCACACCGCAAATCAGTGGACCACAACAGT
ATTCGTTGGTCCTGGGCGATGGAGTGCAAACGCTCCCGCCGTTGGTGGCCCAGATCCTGCAGAACGCTGGTAGTGCGGGC
AACACCAAGCCGTTGACCGTGGAACCCTCAACGCTGGCCAAGATGCCGGTGGTGAATCGGTTGGATCTCTCTGCGTATCC
GGACAATCCCCTGGAAGTGGTGGACATTCGCGAGCATCCGTCGACCTGTTGGTGGTGGGAGCGGACGGCCGGTGAAAACC
GGGCCCGTGTGCGGGTCGTGTCCGGGCCTACCATTCCGGTCGCGGCGACCGAGATGAACAAGGTGGTGTCGTTGGTGAAG
GCCGACACGAGTGGCCGCCAAGCCGATCAGGTCTACTTCGGCCCCGACCATGCGAACTTCGTGGCCGTCACCGGCAACAA
CCCGGGGGCCCAAACGTCCGAATCGCTATGGTGGGTGACCGATGCGGGCGCGCGGTTCGGGGTGGAGGACAGCAAAGAAG
CGCGTGACGCGTTGGGGTTGACCCTGACGCCGAGCCTGGCGCCGTGGGTGGCGCTGCGGCTGCTGCCACAGGGCCCCACG
CTGTCACGAGCGGACGCGTTGGTGGAGCACGACACGCTCCCAATGGACATGACCCCTGCAGAGTTGGTGGTACCGAAATG
A

Upstream 100 bases:

>100_bases
ATGCCCAGTGAAGACACGACGAATCCTTGGGGGATCCGCGCAGTGGCAAATACCCAGGTCAATGTCCAGGTGTTCTGAGC
AGACCGGAAGGTGATCTAGC

Downstream 100 bases:

>100_bases
AGCGTGGTTTTGCCCGCCCGACACCGGAAAAGCCTCCGGTCATCAAGCCCGAGAATATTGTCCTATCGACACCGCTGAGC
ATTCCGCCGCCGGAGGGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component B5; Type VII secretion system protein eccB5; T7SS protein eccB5

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGALLWSFISPSG
QLNESPIIADRDSGALYVRVGDRLYPALNLASARLITGRPDNPHLVRSSQIATMPRGPLVGIPGAPSSFSPKSPPASSWL
VCDTVATSSSIGSLQGVTVTVIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQ
ARPMSRALFDALPVGPELLVPEVPNAGGPATFPGAPGPIGTVIVTPQISGPQQYSLVLGDGVQTLPPLVAQILQNAGSAG
NTKPLTVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHPSTCWWWERTAGENRARVRVVSGPTIPVAATEMNKVVSLVK
ADTSGRQADQVYFGPDHANFVAVTGNNPGAQTSESLWWVTDAGARFGVEDSKEARDALGLTLTPSLAPWVALRLLPQGPT
LSRADALVEHDTLPMDMTPAELVVPK

Sequences:

>Translated_506_residues
MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGALLWSFISPSG
QLNESPIIADRDSGALYVRVGDRLYPALNLASARLITGRPDNPHLVRSSQIATMPRGPLVGIPGAPSSFSPKSPPASSWL
VCDTVATSSSIGSLQGVTVTVIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQ
ARPMSRALFDALPVGPELLVPEVPNAGGPATFPGAPGPIGTVIVTPQISGPQQYSLVLGDGVQTLPPLVAQILQNAGSAG
NTKPLTVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHPSTCWWWERTAGENRARVRVVSGPTIPVAATEMNKVVSLVK
ADTSGRQADQVYFGPDHANFVAVTGNNPGAQTSESLWWVTDAGARFGVEDSKEARDALGLTLTPSLAPWVALRLLPQGPT
LSRADALVEHDTLPMDMTPAELVVPK
>Mature_505_residues
AEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGALLWSFISPSGQ
LNESPIIADRDSGALYVRVGDRLYPALNLASARLITGRPDNPHLVRSSQIATMPRGPLVGIPGAPSSFSPKSPPASSWLV
CDTVATSSSIGSLQGVTVTVIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQA
RPMSRALFDALPVGPELLVPEVPNAGGPATFPGAPGPIGTVIVTPQISGPQQYSLVLGDGVQTLPPLVAQILQNAGSAGN
TKPLTVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHPSTCWWWERTAGENRARVRVVSGPTIPVAATEMNKVVSLVKA
DTSGRQADQVYFGPDHANFVAVTGNNPGAQTSESLWWVTDAGARFGVEDSKEARDALGLTLTPSLAPWVALRLLPQGPTL
SRADALVEHDTLPMDMTPAELVVPK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eccB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECCB5_MYCTU (O53933)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   H70928
- RefSeq:   NP_216298.1
- RefSeq:   NP_336288.1
- EnsemblBacteria:   EBMYCT00000003378
- EnsemblBacteria:   EBMYCT00000072924
- GeneID:   885347
- GeneID:   923804
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1832
- KEGG:   mtu:Rv1782
- TIGR:   MT1832
- TubercuList:   Rv1782
- GeneTree:   EBGT00050000016351
- HOGENOM:   HBG571250
- OMA:   TESLWWL
- ProtClustDB:   CLSK791393
- InterPro:   IPR007795

Pfam domain/function: PF05108 DUF690

EC number: NA

Molecular weight: Translated: 53722; Mature: 53591

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ed90524)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEIEPGRRQTLAVVASV
CCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEHHHHHHH
SAALVICLGALLWSFISPSGQLNESPIIADRDSGALYVRVGDRLYPALNLASARLITGRP
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCCHHCCCCEEEEECCC
DNPHLVRSSQIATMPRGPLVGIPGAPSSFSPKSPPASSWLVCDTVATSSSIGSLQGVTVT
CCCCEEECCCEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCEEEE
VIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQ
EECCCCCCCCCHHEECCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHH
ARPMSRALFDALPVGPELLVPEVPNAGGPATFPGAPGPIGTVIVTPQISGPQQYSLVLGD
CCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECC
GVQTLPPLVAQILQNAGSAGNTKPLTVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHP
CCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHCCCCCEEECCCCCCCCEEEEEECCCC
STCWWWERTAGENRARVRVVSGPTIPVAATEMNKVVSLVKADTSGRQADQVYFGPDHANF
CCEEEEECCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCE
VAVTGNNPGAQTSESLWWVTDAGARFGVEDSKEARDALGLTLTPSLAPWVALRLLPQGPT
EEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCEEECCCHHCEEEEEEECCCCC
LSRADALVEHDTLPMDMTPAELVVPK
CHHHHHHHHCCCCCCCCCCHHEECCH
>Mature Secondary Structure 
AEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEIEPGRRQTLAVVASV
CCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEHHHHHHH
SAALVICLGALLWSFISPSGQLNESPIIADRDSGALYVRVGDRLYPALNLASARLITGRP
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCCHHCCCCEEEEECCC
DNPHLVRSSQIATMPRGPLVGIPGAPSSFSPKSPPASSWLVCDTVATSSSIGSLQGVTVT
CCCCEEECCCEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCEEEE
VIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQ
EECCCCCCCCCHHEECCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHH
ARPMSRALFDALPVGPELLVPEVPNAGGPATFPGAPGPIGTVIVTPQISGPQQYSLVLGD
CCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECC
GVQTLPPLVAQILQNAGSAGNTKPLTVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHP
CCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHCCCCCEEECCCCCCCCEEEEEECCCC
STCWWWERTAGENRARVRVVSGPTIPVAATEMNKVVSLVKADTSGRQADQVYFGPDHANF
CCEEEEECCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCE
VAVTGNNPGAQTSESLWWVTDAGARFGVEDSKEARDALGLTLTPSLAPWVALRLLPQGPT
EEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCEEECCCHHCEEEEEEECCCCC
LSRADALVEHDTLPMDMTPAELVVPK
CHHHHHHHHCCCCCCCCCCHHEECCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036