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The map label for this gene is idi

Identifier: 148661544

GI number: 148661544

Start: 1972898

End: 1973509

Strand: Reverse

Name: idi

Synonym: MRA_1756

Alternate gene names: 148661544

Gene position: 1973509-1972898 (Counterclockwise)

Preceding gene: 148661548

Following gene: 148661543

Centisome position: 44.65

GC content: 64.87

Gene sequence:

>612_bases
ATGACCCGCAGCTACCGGCCAGCTCCACCGATCGAGCGGGTGGTTTTGCTCAACGACCGCGGCGACGCGACAGGTGTGGC
CGACAAGGCCACCGTGCACACCGGCGACACCCCTTTGCACCTCGCGTTCTCCAGCTATGTGTTCGATCTGCACGATCAGC
TGTTGATCACGCGGCGGGCCGCCACCAAGAGGACGTGGCCGGCGGTATGGACCAACAGTTGCTGCGGGCACCCCCTGCCT
GGCGAATCGCTACCCGGCGCCATACGCCGGCGGCTCGCTGCCGAACTCGGACTGACCCCAGATCGGGTCGATCTGATCCT
GCCGGGGTTCCGCTACCGGGCCGCTATGGCCGATGGCACCGTGGAAAACGAGATCTGCCCCGTCTACCGAGTCCAGGTTG
ACCAACAGCCCCGGCCGAACTCGGACGAGGTCGACGCGATCCGCTGGTTGTCCTGGGAACAATTCGTGCGCGATGTTACC
GCCGGCGTAATCGCCCCGGTATCCCCTTGGTGCCGCTCACAACTGGGCTACCTGACCAAACTTGGACCATGTCCGGCACA
GTGGCCCGTGGCCGACGACTGCCGGCTACCGAAAGCCGCACATGGTAATTAA

Upstream 100 bases:

>100_bases
GAGAATCGTGGAACTCCGCACGCGACAAGTGACTCTCCGGTAGTTTGCCAGCGTTGGGGCCGCGAACCGACCCTCGCAAG
CAAGCGTAAGGAGGTCTGGC

Downstream 100 bases:

>100_bases
CCGCTCGATCGCCAGCATCGACAGCATCGCCGTCGCGGGATCGGCCGCGACCACGGGCGCCGTCGCAGTCGCCGGCTCGG
TGGCGACCGCGGGCAGCGTC

Product: isopentenyl-diphosphate delta-isomerase

Products: NA

Alternate protein names: IPP isomerase; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVFDLHDQLLITRRAATKRTWPAVWTNSCCGHPLP
GESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGTVENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVT
AGVIAPVSPWCRSQLGYLTKLGPCPAQWPVADDCRLPKAAHGN

Sequences:

>Translated_203_residues
MTRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVFDLHDQLLITRRAATKRTWPAVWTNSCCGHPLP
GESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGTVENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVT
AGVIAPVSPWCRSQLGYLTKLGPCPAQWPVADDCRLPKAAHGN
>Mature_202_residues
TRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVFDLHDQLLITRRAATKRTWPAVWTNSCCGHPLPG
ESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGTVENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVTA
GVIAPVSPWCRSQLGYLTKLGPCPAQWPVADDCRLPKAAHGN

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI15147242, Length=181, Percent_Identity=28.1767955801105, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI40018633, Length=159, Percent_Identity=29.559748427673, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1789255, Length=166, Percent_Identity=46.3855421686747, Blast_Score=139, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6325140, Length=167, Percent_Identity=28.7425149700599, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362205, Length=191, Percent_Identity=32.9842931937173, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648688, Length=191, Percent_Identity=32.9842931937173, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI_MYCTA (A5U3A5)

Other databases:

- EMBL:   CP000611
- RefSeq:   YP_001283067.1
- ProteinModelPortal:   A5U3A5
- SMR:   A5U3A5
- STRING:   A5U3A5
- EnsemblBacteria:   EBMYCT00000066145
- GeneID:   5211798
- GenomeReviews:   CP000611_GR
- KEGG:   mra:MRA_1756
- eggNOG:   COG1443
- GeneTree:   EBGT00050000018410
- HOGENOM:   HBG416977
- OMA:   ASHPVEG
- ProtClustDB:   PRK03759
- BioCyc:   MTUB419947:MRA_1756-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00202
- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PANTHER:   PTHR10885
- PIRSF:   PIRSF018427
- TIGRFAMs:   TIGR02150

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: =5.3.3.2

Molecular weight: Translated: 22490; Mature: 22359

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS51462 NUDIX

Important sites: ACT_SITE 75-75 ACT_SITE 124-124

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVFDLHDQLLITRRA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
ATKRTWPAVWTNSCCGHPLPGESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGT
HCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCC
VENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVTAGVIAPVSPWCRSQLGYLTK
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGPCPAQWPVADDCRLPKAAHGN
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVFDLHDQLLITRRA
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
ATKRTWPAVWTNSCCGHPLPGESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGT
HCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCC
VENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVTAGVIAPVSPWCRSQLGYLTK
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGPCPAQWPVADDCRLPKAAHGN
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA