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The map label for this gene is 148661532

Identifier: 148661532

GI number: 148661532

Start: 1962292

End: 1962534

Strand: Reverse

Name: 148661532

Synonym: MRA_1744

Alternate gene names: NA

Gene position: 1962534-1962292 (Counterclockwise)

Preceding gene: 148661533

Following gene: 148661531

Centisome position: 44.4

GC content: 64.2

Gene sequence:

>243_bases
ATGACCAACGTCGGTGACCAGGGGGTTGACGCGGTCTTCGGGGTGATCTACCCACCTCAGGTCGCGCTGGTCAGTTTCGG
CAAGCCGGCACAACGAGTTTGCGCCGTCGACGGCGCGATCCACGTCATGACGACCGTGCTGGCTACGCTGCCCGCTGACC
ACGGCTGCAGCGATGACCATCGCGGCGCGCTGTTCTTCCTGTCGATCAACGAGCTGACGCGGTGCGCCGCAGTAACAGGA
TGA

Upstream 100 bases:

>100_bases
GCTCATCGCTGTCATCGAGCGATATCCGACCACTGATCCAAGTCGGGGGCTCTGGGGACCGAAGTCCCCGGGCTCGGAGC
TATCGGACCTCACGATCACC

Downstream 100 bases:

>100_bases
GGATCTGCCCGAAGGCGGTAGCCCCGTCTTGGGACGGTAGGTCAAACCGGGTGTACATACCCGCTCAATCGCCCAGCACT
TCGGGCAGATCACCGGGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDHRGALFFLSINELTRCAAVTG

Sequences:

>Translated_80_residues
MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDHRGALFFLSINELTRCAAVTG
>Mature_79_residues
TNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDHRGALFFLSINELTRCAAVTG

Specific function: Unknown

COG id: COG0508

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 2-oxoacid dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1734_MYCTU (P71992)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   A70688
- RefSeq:   NP_216250.1
- ProteinModelPortal:   P71992
- SMR:   P71992
- EnsemblBacteria:   EBMYCT00000002950
- EnsemblBacteria:   EBMYCT00000095944
- GeneID:   885212
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv1734c
- TIGR:   MT1774.1
- TubercuList:   Rv1734c
- GeneTree:   EBGT00070000032296
- HOGENOM:   HBG128147
- ProtClustDB:   CLSK791359
- InterPro:   IPR001078
- InterPro:   IPR023213
- Gene3D:   G3DSA:3.30.559.10

Pfam domain/function: PF00198 2-oxoacid_dh

EC number: NA

Molecular weight: Translated: 8315; Mature: 8183

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH
CCCCCCCCCHHHEEECCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
RGALFFLSINELTRCAAVTG
CCEEEEEEHHHHHHHHCCCC
>Mature Secondary Structure 
TNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDH
CCCCCCCCHHHEEECCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
RGALFFLSINELTRCAAVTG
CCEEEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036