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The map label for this gene is bcpB

Identifier: 148661403

GI number: 148661403

Start: 1808816

End: 1809280

Strand: Reverse

Name: bcpB

Synonym: MRA_1618

Alternate gene names: 148661403

Gene position: 1809280-1808816 (Counterclockwise)

Preceding gene: 148661415

Following gene: 148661393

Centisome position: 40.93

GC content: 61.29

Gene sequence:

>465_bases
ATGAAAACCGGTGACACGGTAGCCGACTTCGAACTGCCCGATCAGACCGGGACTCCTCGCAGGCTTAGCGTCCTGCTATC
CGACGGACCCGTGGTCCTGTTCTTCTATCCGGCGGCGATGACGCCTGGCTGCACCAAAGAAGCCTGCCACTTCCGCGACT
TGGCCAAAGAATTCGCCGAGGTCAGGGCCAGCCGGGTCGGCATCAGCACCGATCCCGTTCGAAAGCAGGCCAAATTCGCC
GAGGTGCGGCGTTTCGACTACCCGCTGCTTTCGGACGCCCAAGGCACGGTCGCCGCCCAATTCGGGGTCAAGCGCGGTCT
GTTGGGCAAGTTGATGCCGGTCAAACGCACGACCTTTGTCATCGACACCGACCGTAAGGTGCTCGACGTGATCTCCAGCG
AATTCAGCATGGACGCCCACGCCGACAAAGCGTTAGCGACGCTGCGGGCAATCAGATCTGGATAG

Upstream 100 bases:

>100_bases
CCCGACGACGATGCACGCCGCGCAAACGGCGCGCATGGGGGCACCCCCAGCCGCGAAGCGGCGCGCAAGGAGTCGGGCAA
TCGGTTGTAGCCTGACGACT

Downstream 100 bases:

>100_bases
CGGCGGCGAAAACCATCGCTTGCGCACGGATTCATCACGGGACGACGGCAAGAAACAGGTAAGCAGCCAGCAACACCAGA
TGCACCTCGCCCTGCAGACG

Product: putative peroxidoxin BcpB

Products: NA

Alternate protein names: Bacterioferritin comigratory protein; Thioredoxin reductase

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKTGDTVADFELPDQTGTPRRLSVLLSDGPVVLFFYPAAMTPGCTKEACHFRDLAKEFAEVRASRVGISTDPVRKQAKFA
EVRRFDYPLLSDAQGTVAAQFGVKRGLLGKLMPVKRTTFVIDTDRKVLDVISSEFSMDAHADKALATLRAIRSG

Sequences:

>Translated_154_residues
MKTGDTVADFELPDQTGTPRRLSVLLSDGPVVLFFYPAAMTPGCTKEACHFRDLAKEFAEVRASRVGISTDPVRKQAKFA
EVRRFDYPLLSDAQGTVAAQFGVKRGLLGKLMPVKRTTFVIDTDRKVLDVISSEFSMDAHADKALATLRAIRSG
>Mature_154_residues
MKTGDTVADFELPDQTGTPRRLSVLLSDGPVVLFFYPAAMTPGCTKEACHFRDLAKEFAEVRASRVGISTDPVRKQAKFA
EVRRFDYPLLSDAQGTVAAQFGVKRGLLGKLMPVKRTTFVIDTDRKVLDVISSEFSMDAHADKALATLRAIRSG

Specific function: Unknown

COG id: COG1225

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1788825, Length=152, Percent_Identity=38.1578947368421, Blast_Score=99, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322180, Length=106, Percent_Identity=35.8490566037736, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): BCPB_MYCTU (O53911)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842577
- PIR:   G70819
- RefSeq:   NP_216124.1
- RefSeq:   NP_336098.1
- ProteinModelPortal:   O53911
- EnsemblBacteria:   EBMYCT00000000886
- EnsemblBacteria:   EBMYCT00000070506
- GeneID:   885530
- GeneID:   924218
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1643
- KEGG:   mtu:Rv1608c
- TIGR:   MT1643
- TubercuList:   Rv1608c
- GeneTree:   EBGT00050000015906
- HOGENOM:   HBG493509
- OMA:   THADRAL
- ProtClustDB:   CLSK871950
- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: =1.11.1.15

Molecular weight: Translated: 16895; Mature: 16895

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS51352 THIOREDOXIN_2

Important sites: ACT_SITE 44-44

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGDTVADFELPDQTGTPRRLSVLLSDGPVVLFFYPAAMTPGCTKEACHFRDLAKEFAE
CCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
VRASRVGISTDPVRKQAKFAEVRRFDYPLLSDAQGTVAAQFGVKRGLLGKLMPVKRTTFV
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
IDTDRKVLDVISSEFSMDAHADKALATLRAIRSG
EECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTGDTVADFELPDQTGTPRRLSVLLSDGPVVLFFYPAAMTPGCTKEACHFRDLAKEFAE
CCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
VRASRVGISTDPVRKQAKFAEVRRFDYPLLSDAQGTVAAQFGVKRGLLGKLMPVKRTTFV
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
IDTDRKVLDVISSEFSMDAHADKALATLRAIRSG
EECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036