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The map label for this gene is frdC

Identifier: 148661350

GI number: 148661350

Start: 1761692

End: 1762072

Strand: Direct

Name: frdC

Synonym: MRA_1566

Alternate gene names: 148661350

Gene position: 1761692-1762072 (Clockwise)

Preceding gene: 148661349

Following gene: 148661351

Centisome position: 39.86

GC content: 59.84

Gene sequence:

>381_bases
ATGAGCGCCTATCGCCAGCCGGTCGAAAGATACTGGTGGGCGAGGCGGCGTTCTTACCTGCGATTCATGCTTCGCGAAAT
CAGTTGCATCTTCGTGGCCTGGTTTGTTCTCTATCTGATGCTGGTATTGCGCGCCGTTGGCGCGGGCGGGAATTCCTACC
AGCGGTTTTTGGACTTCAGCGCCAATCCGGTTGTCGTAGTGCTGAACGTCGTCGCGTTGAGTTTCCTGCTGCTGCATGCT
GTTACCTGGTTCGGATCGGCACCGCGCGCGATGGTGATTCAGGTTCGCGGCCGCCGGGTACCCGCTCGCGCGGTCCTTGC
TGGGCACTACGCGGCATGGCTGGTGGTTTCGGTGATCGTTGCCTGGATGGTGCTGTCATGA

Upstream 100 bases:

>100_bases
CTTGTCCGAAAGGCGTCGATCCTGCCGGCGCGATCCAGCGCTACAAGCTGACCGCGGCCACGCACGCGCTGAAGAAGTTG
CTGTTCCCTTGGGGGGGCGG

Downstream 100 bases:

>100_bases
CTCCCTCGACATCGGATGCCAGGTCGCGCCGACGCTCGGCGGAGCCCTTCCTGTGGCTGCTGTTCAGCGCCGGGGGCATG
GTCACCGCCCTGGTTGCGCC

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MSAYRQPVERYWWARRRSYLRFMLREISCIFVAWFVLYLMLVLRAVGAGGNSYQRFLDFSANPVVVVLNVVALSFLLLHA
VTWFGSAPRAMVIQVRGRRVPARAVLAGHYAAWLVVSVIVAWMVLS

Sequences:

>Translated_126_residues
MSAYRQPVERYWWARRRSYLRFMLREISCIFVAWFVLYLMLVLRAVGAGGNSYQRFLDFSANPVVVVLNVVALSFLLLHA
VTWFGSAPRAMVIQVRGRRVPARAVLAGHYAAWLVVSVIVAWMVLS
>Mature_125_residues
SAYRQPVERYWWARRRSYLRFMLREISCIFVAWFVLYLMLVLRAVGAGGNSYQRFLDFSANPVVVVLNVVALSFLLLHAV
TWFGSAPRAMVIQVRGRRVPARAVLAGHYAAWLVVSVIVAWMVLS

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family

Homologues:

Organism=Escherichia coli, GI1790595, Length=124, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDC_MYCTA (A5U2R1)

Other databases:

- EMBL:   CP000611
- RefSeq:   YP_001282873.1
- ProteinModelPortal:   A5U2R1
- SMR:   A5U2R1
- STRING:   A5U2R1
- EnsemblBacteria:   EBMYCT00000067765
- GeneID:   5212480
- GenomeReviews:   CP000611_GR
- KEGG:   mra:MRA_1566
- eggNOG:   COG3029
- GeneTree:   EBGT00050000016376
- HOGENOM:   HBG567671
- OMA:   KMGPEPV
- ProtClustDB:   PRK13603
- BioCyc:   MTUB419947:MRA_1566-MONOMER
- HAMAP:   MF_00708
- InterPro:   IPR003510
- ProDom:   PD015900

Pfam domain/function: PF02300 Fumarate_red_C

EC number: 1.3.99.1

Molecular weight: Translated: 14449; Mature: 14318

Theoretical pI: Translated: 11.95; Mature: 11.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e5e8bfc)-; HASH(0x1d9a42d8)-; HASH(0x1e40f624)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYRQPVERYWWARRRSYLRFMLREISCIFVAWFVLYLMLVLRAVGAGGNSYQRFLDFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
ANPVVVVLNVVALSFLLLHAVTWFGSAPRAMVIQVRGRRVPARAVLAGHYAAWLVVSVIV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AWMVLS
HHHHCH
>Mature Secondary Structure 
SAYRQPVERYWWARRRSYLRFMLREISCIFVAWFVLYLMLVLRAVGAGGNSYQRFLDFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
ANPVVVVLNVVALSFLLLHAVTWFGSAPRAMVIQVRGRRVPARAVLAGHYAAWLVVSVIV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AWMVLS
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA