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The map label for this gene is fadD11

Identifier: 148661346

GI number: 148661346

Start: 1755233

End: 1756948

Strand: Direct

Name: fadD11

Synonym: MRA_1562

Alternate gene names: 148661346

Gene position: 1755233-1756948 (Clockwise)

Preceding gene: 148661345

Following gene: 148661347

Centisome position: 39.71

GC content: 64.63

Gene sequence:

>1716_bases
ATGGCGAGACTACGCGGCGCAGGTGCGGCGGGTCGCTGCCGGCCTGGCAGGTTTGGGAGTTCGGCGCGGCGACACGGTCT
CGCTGATGATGGCGAACCGGATCGAGTTCTACCCGCTCGACGTCGGTGCTCAGCACGTCGGCGCCACCTCGTTTTCGGTG
TACAACACCCTGCCCGCCGAGCAGCTGACCTACGTGTTCGACAACGCGGGGACCAAGGTGGTCATCTGCGAGCAACAGTA
CGTCGATCGCGTTCGCGCCAGCGGTGTGCCCATCGAACACATCGTCTGCGTCGATGGCGCGCCCCCGGCACGCTCTCGCT
GACGGATTTGTACGCGGCCGCCTCCGGCGACTTCTTCGACTTCGAGTCGACGTGGCGTGCCGTACAACCCGAGGACATTG
TCACCCTCATCTACACGTCCGGCACAACGGGAAACCCCAAGGGTGTGGAGATGACCCACGCCAACCTGCTGTTCGAGGGG
TATGCCATCGACGAGGTGCTCGGAATCCGGTTTGGCGATCGGGTGACGTCCTTCCTGCCATCGGCGCACATCGCCGATCG
GATGACCGGGCTGTACCTGCAGGAGATGTTCGGCACCCAGGTCACCGCGGTGGCCGACGCGCGCACGATCGCAGCCGCGC
TCCCCGACGTGCGGCCAACCGTGTGGGGGGCCGTTCCCCGGGTTTGGGAAAAGCTTAAGGCCGGAATCGAATTCACCGTC
GCTCGTGAGACCGACGAGATGAAGCGGCAGGCGTTGGCGTGGGCGATGTCGGTGGCTGGCAAACGCGCCAACGCCCTGCT
CGCAGGTGAATCTATGTCGGATCAGCTGGTCGCCGAATGGGCCAAAGCCGACGAGTTGGTGTTGTCCAAGTTGCGCGAGC
GGCTGGGCTTCGGCGAGCTGCGGTGGGCCCTGTCCGGAGCGGCGCCGATCCCCAAGGAGACGCTCGCGTTCTTCGCAGGT
ATCGGCATCCCAATCGCCGAGATTTGGGGAATGTCGGAGCTGAGCTGCGTTGCCACCGCCAGCCATCCCCGCGACGGGCG
GCTGGGCACCGTCGGAAAACTACTTCCCGGGCTGCAGGGCAAGATCGCCGAAGACGGTGAGTACCTGGTCCGCGGTCCGC
TGGTGATGAAGGGTTATCGCAAAGAACCGGCCAAGACCGCGGAGGCGATCGACTCCGACGGCTGGCTACACACCGGAGAT
GTCTTCGATATCGACTCCGACGGCTATCTGCGGGTGGTGGACCGCAAGAAGGAGCTGATCATCAATGCGGCCGGAAAAAA
CATGTCGCCGGCCAACATCGAGAACACCATCCTGGCCGCGTGCCCCATGGTCGGGGTGATGATGGCAATCGGTGACGGGC
GAACGTATAACACCGCGCTGTTGGTCTTCGACGCCGACTCTCTCGGTCCGTATGCGGCCCAGCGTGGCCTCGATGCCTCG
CCCGCGGCTCTGGCGGCTGACCCGGAGGTGATCGCGCGCATCGCCGCCGGCGTGGCCGAGGGCAACGCCAAATTATCGCG
GGTCGAACAGATCAAGCGGTTCCGCATATTGCCCACCCTGTGGGAGCCCGGCGGGGACGAGATAACCCTGACGATGAAAC
TCAAGCGCCGTCGAATCGCCGCGAAATATTCCGCGGAGATCGAGGAGCTCTACGCCAGCGAGCTGAGACCGCAGGTTTAC
GAGCCCGCTGCCGTGCCATCGACACAACCGGCATGA

Upstream 100 bases:

>100_bases
CAGAGCGCCCGACAACCATGTGCGAGGCGTTCCAGCGCACCGCCGTCATGGACCCGGACGCCGTTGCGCTACGGACCCCC
GGCGGTAACCAGACAATGAC

Downstream 100 bases:

>100_bases
CGGGGGCTAGCCAGTGACTGCACGGGAGGTGGGCCGCATCGGACTGCGAAAGTTGCTGCAGCGCATCGGTATTGTTGCTG
AATCAATGACGCCGCTAGCG

Product: fatty-acid-CoA ligase FadD11

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Acyl-CoA synthetase

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MARLRGAGAAGRCRPGRFGSSARRHGLADDGEPDRVLPARRRCSARRRHLVFGVQHPARRAADLRVRQRGDQGGHLRATV
RRSRSRQRCAHRTHRLRRWRAPGTLSLTDLYAAASGDFFDFESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFEG
YAIDEVLGIRFGDRVTSFLPSAHIADRMTGLYLQEMFGTQVTAVADARTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTV
ARETDEMKRQALAWAMSVAGKRANALLAGESMSDQLVAEWAKADELVLSKLRERLGFGELRWALSGAAPIPKETLAFFAG
IGIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPGLQGKIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGD
VFDIDSDGYLRVVDRKKELIINAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYNTALLVFDADSLGPYAAQRGLDAS
PAALAADPEVIARIAAGVAEGNAKLSRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIAAKYSAEIEELYASELRPQVY
EPAAVPSTQPA

Sequences:

>Translated_571_residues
MARLRGAGAAGRCRPGRFGSSARRHGLADDGEPDRVLPARRRCSARRRHLVFGVQHPARRAADLRVRQRGDQGGHLRATV
RRSRSRQRCAHRTHRLRRWRAPGTLSLTDLYAAASGDFFDFESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFEG
YAIDEVLGIRFGDRVTSFLPSAHIADRMTGLYLQEMFGTQVTAVADARTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTV
ARETDEMKRQALAWAMSVAGKRANALLAGESMSDQLVAEWAKADELVLSKLRERLGFGELRWALSGAAPIPKETLAFFAG
IGIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPGLQGKIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGD
VFDIDSDGYLRVVDRKKELIINAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYNTALLVFDADSLGPYAAQRGLDAS
PAALAADPEVIARIAAGVAEGNAKLSRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIAAKYSAEIEELYASELRPQVY
EPAAVPSTQPA
>Mature_570_residues
ARLRGAGAAGRCRPGRFGSSARRHGLADDGEPDRVLPARRRCSARRRHLVFGVQHPARRAADLRVRQRGDQGGHLRATVR
RSRSRQRCAHRTHRLRRWRAPGTLSLTDLYAAASGDFFDFESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFEGY
AIDEVLGIRFGDRVTSFLPSAHIADRMTGLYLQEMFGTQVTAVADARTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTVA
RETDEMKRQALAWAMSVAGKRANALLAGESMSDQLVAEWAKADELVLSKLRERLGFGELRWALSGAAPIPKETLAFFAGI
GIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPGLQGKIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDV
FDIDSDGYLRVVDRKKELIINAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYNTALLVFDADSLGPYAAQRGLDASP
AALAADPEVIARIAAGVAEGNAKLSRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIAAKYSAEIEELYASELRPQVYE
PAAVPSTQPA

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family

Homologues:

Organism=Homo sapiens, GI27477105, Length=456, Percent_Identity=34.8684210526316, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI83745141, Length=460, Percent_Identity=30.6521739130435, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI57165412, Length=443, Percent_Identity=30.6997742663657, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI40807491, Length=443, Percent_Identity=31.1512415349887, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI57165410, Length=443, Percent_Identity=30.2483069977427, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI42794756, Length=440, Percent_Identity=29.0909090909091, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI42794760, Length=440, Percent_Identity=29.0909090909091, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI42794758, Length=440, Percent_Identity=29.0909090909091, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI4758332, Length=460, Percent_Identity=26.304347826087, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI12669909, Length=461, Percent_Identity=26.0303687635575, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI42794754, Length=459, Percent_Identity=27.0152505446623, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI42794752, Length=459, Percent_Identity=27.0152505446623, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI187761345, Length=317, Percent_Identity=28.0757097791798, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI187761343, Length=317, Percent_Identity=28.0757097791798, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI156151445, Length=121, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1788107, Length=337, Percent_Identity=26.7062314540059, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789201, Length=371, Percent_Identity=24.5283018867925, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693145, Length=151, Percent_Identity=32.4503311258278, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17510401, Length=441, Percent_Identity=32.6530612244898, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17564090, Length=450, Percent_Identity=29.7777777777778, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17556552, Length=451, Percent_Identity=27.2727272727273, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI25147511, Length=458, Percent_Identity=28.6026200873362, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17553312, Length=456, Percent_Identity=30.4824561403509, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17541856, Length=444, Percent_Identity=27.027027027027, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193204819, Length=471, Percent_Identity=24.8407643312102, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17558820, Length=315, Percent_Identity=27.9365079365079, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32563687, Length=313, Percent_Identity=28.4345047923323, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17559526, Length=178, Percent_Identity=34.2696629213483, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531443, Length=171, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71996755, Length=162, Percent_Identity=32.0987654320988, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320852, Length=459, Percent_Identity=27.6688453159041, Blast_Score=160, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6322182, Length=450, Percent_Identity=24.4444444444444, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323903, Length=456, Percent_Identity=25.219298245614, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324893, Length=452, Percent_Identity=23.6725663716814, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17933690, Length=484, Percent_Identity=30.5785123966942, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI19921316, Length=472, Percent_Identity=31.9915254237288, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281366413, Length=440, Percent_Identity=29.7727272727273, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24666501, Length=440, Percent_Identity=29.7727272727273, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24666497, Length=440, Percent_Identity=29.7727272727273, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI62471679, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471683, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471685, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24586636, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471689, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471681, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471687, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24586634, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI22026970, Length=474, Percent_Identity=26.7932489451477, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24581924, Length=359, Percent_Identity=25.6267409470752, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648257, Length=364, Percent_Identity=25.2747252747253, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355181, Length=160, Percent_Identity=34.375, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356947, Length=133, Percent_Identity=33.8345864661654, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FAD11_MYCTU (Q10776)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   C70762
- RefSeq:   NP_216066.1
- RefSeq:   NP_336053.1
- ProteinModelPortal:   Q10776
- EnsemblBacteria:   EBMYCT00000002537
- EnsemblBacteria:   EBMYCT00000072135
- GeneID:   886380
- GeneID:   924341
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1600
- KEGG:   mtu:Rv1550
- TIGR:   MT1600
- TubercuList:   Rv1550
- GeneTree:   EBGT00070000031856
- HOGENOM:   HBG721674
- OMA:   EHIVCID
- ProtClustDB:   CLSK791242
- InterPro:   IPR020845
- InterPro:   IPR000873

Pfam domain/function: PF00501 AMP-binding

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 62310; Mature: 62179

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d510a54)-; HASH(0x1e490e3c)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLRGAGAAGRCRPGRFGSSARRHGLADDGEPDRVLPARRRCSARRRHLVFGVQHPARR
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHCEEEEECCCHHHH
AADLRVRQRGDQGGHLRATVRRSRSRQRCAHRTHRLRRWRAPGTLSLTDLYAAASGDFFD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCCC
FESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFEGYAIDEVLGIRFGDRVTSFLP
CHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEEHEEEEECCCHHHHHHCHHHHHHHHHCC
SAHIADRMTGLYLQEMFGTQVTAVADARTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTV
CHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEE
ARETDEMKRQALAWAMSVAGKRANALLAGESMSDQLVAEWAKADELVLSKLRERLGFGEL
ECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RWALSGAAPIPKETLAFFAGIGIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPGLQG
HHHHCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCC
KIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDVFDIDSDGYLRVVDRKKELI
CCCCCCCEEEECCEEECCCCCCHHHHHHHHCCCCCEECCCEEEECCCCEEEEECCCCEEE
INAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYNTALLVFDADSLGPYAAQRGLDAS
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHCCCCCC
PAALAADPEVIARIAAGVAEGNAKLSRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIA
CCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHHHHH
AKYSAEIEELYASELRPQVYEPAAVPSTQPA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
ARLRGAGAAGRCRPGRFGSSARRHGLADDGEPDRVLPARRRCSARRRHLVFGVQHPARR
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHCEEEEECCCHHHH
AADLRVRQRGDQGGHLRATVRRSRSRQRCAHRTHRLRRWRAPGTLSLTDLYAAASGDFFD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCCC
FESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFEGYAIDEVLGIRFGDRVTSFLP
CHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEEHEEEEECCCHHHHHHCHHHHHHHHHCC
SAHIADRMTGLYLQEMFGTQVTAVADARTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTV
CHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEE
ARETDEMKRQALAWAMSVAGKRANALLAGESMSDQLVAEWAKADELVLSKLRERLGFGEL
ECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RWALSGAAPIPKETLAFFAGIGIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPGLQG
HHHHCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCC
KIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDVFDIDSDGYLRVVDRKKELI
CCCCCCCEEEECCEEECCCCCCHHHHHHHHCCCCCEECCCEEEECCCCEEEEECCCCEEE
INAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYNTALLVFDADSLGPYAAQRGLDAS
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHCCCCCC
PAALAADPEVIARIAAGVAEGNAKLSRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIA
CCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHHHHH
AKYSAEIEELYASELRPQVYEPAAVPSTQPA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0024 {myristate}} 0.0021 {myristate}} 0.0012 {myristate}} 0.0002 {myristate}} 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0112 {hexanoate}} 0.0083 {decanoate}} 0.0063 {decanoate}} 0.0043 {dec

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036