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The map label for this gene is ppe21

Identifier: 148661344

GI number: 148661344

Start: 1752814

End: 1754850

Strand: Reverse

Name: ppe21

Synonym: MRA_1560

Alternate gene names: 148661344

Gene position: 1754850-1752814 (Counterclockwise)

Preceding gene: 148661358

Following gene: 148661338

Centisome position: 39.7

GC content: 62.1

Gene sequence:

>2037_bases
ATGAATTTTTCGGTGTTGCCGCCGGAGATCAATTCGGCGCTGATGTTCGCTGGTGCCGGGCCGGGACCGATGTTGGCGGC
GGCGTCGGCCTGGACCGGGCTGGCCGGCGATTTGGGTTCGGCGGCGGCCTCATTTTCGGCGGTGACCTCGCAGTTGGCCA
CCGGGTCCTGGCAAGGTCCGGCGTCAGCGGCCATGACAGGCGTGGCCGCGTCCTATGCTCGCTGGCTGACCACGGCCGCA
GCGCAGGCTGAGCAGGCGGCGGGTCAAGCCCAGGCGGCGGTATCGGCGTTCGAGGCGGCGCTGGCGGCGACGGTGCATCC
GGGCGCGGTGAGCGCCAATCGAGGTCGGTTGCGCTCCTTGGTGGCCTCGAATCTGTTGGGGCAAAACGCCCCGGCCATCG
CGGCCGTCGAGGCCGTCTATGAGCAGATGTGGGCCGCCGATGTCGCCGCGATGCTCGGTTATCACGGCGAGGCGTCGGCG
GTCGCCTTGTCGCTGACGCCGTTCACACCGTCGCCGAGCGCGGCAGCCACGCCCGGCGGTGCGGTGATCATCGCGGGGTT
TCCGTTTCTCGATCTGGGCAACGTCACCATCGGTGGCTTCAATCTGGCCAGCGGCAATCTGGGCCTCGGCAACCTGGGCA
GCTTCAACCCGGGTAGCGCCAACACGGGCAGCGTCAACTTGGGCAACGCCAATATCGGTGATCTCAACCTGGGCAGCGGC
AATATCGGCAGCTACAACCTGGGTGGCGGCAACACCGGGGATCTCAACCCGGACAGTGGAAACACGGGCACGCTCAACTG
GGGTAGCGGAAACATCGGCAGCTATAACCTGGGCGGCGGCAACCTCGGCAGCTATAACCTGGGTAGTGGAAATACCGGCG
ACACCAACTTTGGCGGCGGTAACACCGGAAATCTCAACGTGGGTGGCGGCAACACCGGGAACTCGAATTTCGGGTTCGGA
AACACCGGTAACGTCAACTTTGGTAACGGAAACACCGGCGACACCAACTTTGGCAGCGGCAACCTTGGCAGTGGAAATAT
CGGTTTCGGCAACAAGGGCTCTCATAACATCGGGTTTGGGAACAGCGGCAACAACAACATCGGCTTCGGGCTCACCGGTG
ATAACCAGATAGGTTTCGGCGCCCTCAATTCAGGTAGCGGGAACCTCGGCTTCGGGAACTCGGGCAACGGTAATATCGGC
TTTTTCAACTCGGGCAATAACAACATCGGCATGGGAAACTCGGGCAATGGAGTCGGGGCGCTGAGCGTGGAGTTCGGCAG
TTCGGCCGAGCGCAGCTCGGGCTTCGGCAACTCCGGCGAGCTCAGTACCGGTATCGGCAACTCCGGCCAGCTCAGCACGG
GCTGGTTCAACTCGGCCACCACCAGCACCGGCTGGTTCAACTCCGGCACCACCAATACCGGCTGGTTCAACTCGGGCACC
ACGAACACCGGAATCGGAAACTCGGGCGGAAACCTGGTCACCGGCAGCATGGGTCTGTTTAACTCCGGCCATACCAACAC
GGGTAGCTTCAATGCCGGCAGCATGAACACGGGCGATTTCAACTCGGGCAACGTGAACACCGGCTACTTCAACTCCGGCA
ACATCAACACCGGCTTCTTCAACTCGGGCGATCTCAACACCGGATTGTTCAACTCGGTCAACCAGCCGGTACAGAACTCC
GGCTGGCTGCACACGGGCACCAACAACTCGGGCTACGCTAACGCCGGCACCTTCAACTCGGGCTTCGATAACAACGCCCG
TGACGAACACGCCGAATTTGTCACCGGTAACTCGGGCCTGGCCAACGTGGGCAACTACAACGCCGGCATCATCAACGTGG
GTGACCATCTGTCGGGCTTCAGAAACTCGGTACCCACGATCACCGGTACGGCCAACATTTCGGGTTTCGTCAATGCGGGA
ACCTCGATCTCTGGCTTCTTCAACTTCGGCAGCCTCATGTCGGGCTTCGCCAACTTCGACGACGAGGTCTCGGGGTATCT
CAACGGGGACAGTCGGGCGTCGGGCTGGATCCATTAG

Upstream 100 bases:

>100_bases
CCCGTCCGAAGCGCCCGGCTTTTTCGTAGGCTTCGCTGCGGTTGGGGCCAGACAGCGCCGTGAAGCCCGGTGGGTGTGGC
CGGCTGACGGGATGGTTGTG

Downstream 100 bases:

>100_bases
CGGCGCTCACGGGCGATCGTGCGGAAACCGCTGGGGGCGGTCGCCTCGCTAACTCCCCAGACATCCAGGGCCGAGCAGCT
CCTTGAGGTCACCCATCAAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAA
AQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASA
VALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
NIGSYNLGGGNTGDLNPDSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFG
NTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIG
FFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNS
GWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAG
TSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH

Sequences:

>Translated_678_residues
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAA
AQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASA
VALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
NIGSYNLGGGNTGDLNPDSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFG
NTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIG
FFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNS
GWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAG
TSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH
>Mature_678_residues
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAA
AQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASA
VALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
NIGSYNLGGGNTGDLNPDSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFG
NTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIG
FFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNS
GWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAG
TSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE21_MYCTU (Q10778)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   A70762
- RefSeq:   NP_336052.1
- RefSeq:   YP_177817.1
- ProteinModelPortal:   Q10778
- SMR:   Q10778
- EnsemblBacteria:   EBMYCT00000002192
- EnsemblBacteria:   EBMYCT00000071955
- GeneID:   886384
- GeneID:   924340
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1599
- KEGG:   mtu:Rv1548c
- TIGR:   MT1599
- TubercuList:   Rv1548c
- GeneTree:   EBGT00050000014886
- HOGENOM:   HBG572308
- OMA:   STGVYFT
- ProtClustDB:   CLSK799815
- InterPro:   IPR002989
- InterPro:   IPR000030

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE

EC number: NA

Molecular weight: Translated: 66737; Mature: 66737

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e577c74)-; HASH(0x1e791b4c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGP
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ASAAMTGVAASYARWLTTAAAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
VASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASAVALSLTPFTPSPSAAATPGG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCC
AVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
EEEEECCCCEEECCEEECCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCCC
NIGSYNLGGGNTGDLNPDSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGG
CCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCEECCCCCCCCCCCCCC
NTGNLNVGGGNTGNSNFGFGNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFG
CCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIGFFNSGNNNIGMGNSGNGVGA
CCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
LSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
EEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFF
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEE
NSGDLNTGLFNSVNQPVQNSGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGL
CCCCCCCHHHHHCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
ANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAGTSISGFFNFGSLMSGFANFD
CCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCCEEEECCCCEEHHHHHHHHHHHHHCCC
DEVSGYLNGDSRASGWIH
CHHCEEECCCCCCCCCCH
>Mature Secondary Structure
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGP
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ASAAMTGVAASYARWLTTAAAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
VASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASAVALSLTPFTPSPSAAATPGG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCC
AVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
EEEEECCCCEEECCEEECCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCCC
NIGSYNLGGGNTGDLNPDSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGG
CCCEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCEECCCCCCCCCCCCCC
NTGNLNVGGGNTGNSNFGFGNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFG
CCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIGFFNSGNNNIGMGNSGNGVGA
CCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
LSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
EEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFF
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEE
NSGDLNTGLFNSVNQPVQNSGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGL
CCCCCCCHHHHHCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
ANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAGTSISGFFNFGSLMSGFANFD
CCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCCEEEECCCCEEHHHHHHHHHHHHHCCC
DEVSGYLNGDSRASGWIH
CHHCEEECCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036