BacMap

Definition	Mycobacterium tuberculosis H37Ra, complete genome.
Accession	NC_009525
Length	4,419,977

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The map label for this gene is yqjQ [H]

Identifier: 148661340

GI number: 148661340

Start: 1747611

End: 1748414

Strand: Direct

Name: yqjQ [H]

Synonym: MRA_1556

Alternate gene names: 148661340

Gene position: 1747611-1748414 (Clockwise)

Preceding gene: 148661339

Following gene: 148661341

Centisome position: 39.54

GC content: 65.3

Gene sequence:

>804_bases
ATGAGCCTTCCGAAACCGAACAATCAGACCACCGTTGTGATCACCGGCGCCTCCTCCGGCATCGGTGTCGAATTGGCTCG
TGGCTTGGCCGGCCGCGGCTTCCCACTGATGCTAGTGGCGCGGCGCCGCGAGCGCCTCGACGAACTGGCCGATCAGCTGC
GCCAGGAACACTGCGTCGGGGTGGAGGTCTTGCCGCTCGACCTTGCCGATACGCAAGCGAGGGCACAGCTGGCTGATCGC
TTGCGTAGTGATGCGATTGCCGGGCTGTGCAACAGCGCAGGTTTCGGCACCAGTGGGCGTTTTTGGGAGTTGCCGTTCGC
ACGCGAAAGCGAGGAAGTCGTCCTCAATGCTCTGGCGTTAATGGAACTCACCCATGCCGCACTGCCAGGCATGGTCAAGC
GCGGCGCCGGTGCGGTGCTCAACATCGCCTCGATCGCGGGTTTCCAGCCGATTCCCTATATGGCCGTGTATTCGGCTACC
AAAGCCTTTGTGCTGACGTTCTCTGAAGCCGTGCAGGAGGAGCTGCACGGAACGGGCGTGTCGGTGACTGCCCTGTGCCC
AGGCCCGGTACCCACCGAGTGGGCCGAGATCGCCAGCGCCGAGCGGTTCAGCATTCCCCTCGCCCAAGTTTCGCCGCACG
ACGTCGCCGAAGCCGCCATCGCCGGGATGCTCTCCGGTAAGCGCACCGTCGTGCCGGGCATAGTGCCAAAGTTCGTCAGC
ACCAGCGGCAGATTCGCTCCGCGCAGCCTGCTGCTGCCCGCGATCCGGATCGGCAACCGGCTGCGCGGCGGGCCCAGCCG
CTGA

Upstream 100 bases:

>100_bases
TCCGCAGCCAAGGGAAGTGAATCCCAAACCGACACATCAGAACTCGACAAGCGAAGCGAGACGTTTGTGCGGGCCACCCG
AGGGATCCATTGGTGACACC

Downstream 100 bases:

>100_bases
TGTGAGGGGCGTTCCGGCCTGGTGCCGAACGGAGTGCTGGGCCTGGGCAATCCCAGCCGGCTAGCCGCGTTGTATGGGTT
GCAGCTGGCGCACGAGTCGC

Product: putative short-chain type dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADR
LRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSAT
KAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVS
TSGRFAPRSLLLPAIRIGNRLRGGPSR

Sequences:

>Translated_267_residues
MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADR
LRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSAT
KAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVS
TSGRFAPRSLLLPAIRIGNRLRGGPSR
>Mature_266_residues
SLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADRL
RSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSATK
AFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVST
SGRFAPRSLLLPAIRIGNRLRGGPSR

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=32.2751322751323, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=30.8510638297872, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI20149619, Length=234, Percent_Identity=30.3418803418803, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4557649, Length=183, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=32.4607329842932, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI7657478, Length=202, Percent_Identity=29.7029702970297, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI223718074, Length=193, Percent_Identity=30.0518134715026, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI210032110, Length=244, Percent_Identity=24.1803278688525, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI142976729, Length=264, Percent_Identity=25.3787878787879, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=28.2828282828283, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI44680133, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI17738292, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=30.0429184549356, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI150247226, Length=197, Percent_Identity=30.4568527918782, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787820, Length=220, Percent_Identity=34.0909090909091, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786701, Length=258, Percent_Identity=26.7441860465116, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=31.2169312169312, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790717, Length=207, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787335, Length=200, Percent_Identity=25, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=26.4822134387352, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=216, Percent_Identity=28.7037037037037, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17557668, Length=207, Percent_Identity=28.0193236714976, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI212646214, Length=205, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17559552, Length=207, Percent_Identity=27.0531400966184, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=186, Percent_Identity=30.6451612903226, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17532725, Length=233, Percent_Identity=24.8927038626609, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560176, Length=186, Percent_Identity=27.9569892473118, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=210, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=269, Percent_Identity=25.6505576208178, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=269, Percent_Identity=25.6505576208178, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=233, Percent_Identity=23.175965665236, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=200, Percent_Identity=30.5, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=32.3076923076923, Blast_Score=82, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=32.0197044334975, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24584744, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28574402, Length=188, Percent_Identity=31.3829787234043, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=28.7958115183246, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=30.8900523560209, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI116007236, Length=220, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=31.4285714285714, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580925, Length=204, Percent_Identity=30.8823529411765, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357041, Length=239, Percent_Identity=29.7071129707113, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364494, Length=225, Percent_Identity=29.3333333333333, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397609, Length=185, Percent_Identity=32.972972972973, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584752, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648944, Length=225, Percent_Identity=30.6666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007238, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643142, Length=230, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24651139, Length=252, Percent_Identity=25.7936507936508, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28200; Mature: 28069

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELADQLRQEHCVG
CCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLNALAL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHH
MELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSATKAFVLTFSEAVQEELHGTGV
HHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVS
EEEEECCCCCCHHHHHHHCCHHHCCCHHHCCCHHHHHHHHHHHHCCCCEECCCHHHHHHC
TSGRFAPRSLLLPAIRIGNRLRGGPSR
CCCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELADQLRQEHCVG
CCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLNALAL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHH
MELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSATKAFVLTFSEAVQEELHGTGV
HHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVS
EEEEECCCCCCHHHHHHHCCHHHCCCHHHCCCHHHHHHHHHHHHCCCCEECCCHHHHHHC
TSGRFAPRSLLLPAIRIGNRLRGGPSR
CCCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]