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The map label for this gene is 148661322

Identifier: 148661322

GI number: 148661322

Start: 1722297

End: 1723577

Strand: Reverse

Name: 148661322

Synonym: MRA_1538

Alternate gene names: NA

Gene position: 1723577-1722297 (Counterclockwise)

Preceding gene: 148661323

Following gene: 148661318

Centisome position: 39.0

GC content: 65.18

Gene sequence:

>1281_bases
ATGAAGTTTGTCTTGGCGGTCCACGGAACCCGCGGTGATGTCGAACCTTGCGCCGCGGTTGGCGTGGAGCTGCGGCGGCG
AGGCCACGCAGTTCATATGGCAGTGCCGCCCAACCTGATCGAGTTCGTCGAGTCGGCAGGTCTGACCGGCGTCGCCTACG
GCCCGGACTCGGACGAACAGATCAACACGGTCGCGGCATTCGTCCGCAACCTCACCAGAGCCCAGAATCCGCTCAACCTC
GCCCGCGCCGTCAAGGAACTATTCGTCGAAGGCTGGGCGGAGATGGGCACGACGTTGACCACGTTGGCCGACGGCGCCGA
CCTGGTGATGACGGGCCAGACATATCATGGTGTGGCAGCCAACGTCGCCGAGTACTACGACATTCCGGCTGCGGCACTGC
ATCACTTTCCGATGCAGGTCAACGGCCAAATCGCGATCCCGTCGATACCGACGCCGGCGACTCTGGTGCGCGCGACGATG
AAGGTCTCATGGCGGCTGTATGCGTACGTCAGCAAGGATGCCGATCGCGCGCAACGACGTGAACTGGGCCTACCGCCAGC
ACCGGCGCCGGCGGTGCGTCGGCTGGCGGAACGCGGAGCGCCCGAAATCCAAGCCTACGACCCGGTTTTTTTCCCCGGAC
TGGCGGCCGAATGGAGCGACCGCCGCCCGTTTGTCGGCCCGCTGACCATGGAGTTACACAGCGAACCCAACGAAGAACTC
GAGTCGTGGATCGCCGCCGGAACACCACCCATCTACTTCGGCTTCGGCAGCACGCCCGTCCAAACGCCCGTCCAAACGCT
CGCCATGATCTCCGATGTCTGCGCACAGCTCGGCGAGCGAGCCCTGATCTATTCTCCGGCAGCCAACTCCACCCGCATTC
GTCATGCCGACCACGTGAAACGTGTCGGCCTGGTCAACTATTCGACCATCCTTCCCAAGTGCCGCGCGGTCGTCCACCAC
GGTGGCGCCGGTACCACCGCCGCCGGCCTGCGAGCGGGAATGCCCACGCTGATTCTCTGGGACGTGGCCGATCAACCGAT
CTGGGCCGGTGCCGTCCAACGACTCAAAGTCGGCTCTGCCAAACGCTTTACGAACATCACCCGCGGGTCATTGCTCAAGG
AGCTACGATCGATCCTGGCGCCGGAATGCGCCGCGCGGGCACGTGAGATCTCGACACGGATGACCCGGCCGACAGCCGCC
GTCACCGCGGCCGCGGACCTGCTGGAGGCGACGGCACGCCAAACGCCTGGGAGCACGCCTAGCAGCTCGCCGGGCAGGTG
A

Upstream 100 bases:

>100_bases
AACACCACCGTTCGTGGCCTGGCGGATCTGATGTGCGACAAGTTGGCGGCCGACAGGGACGCGCCGGCACCCGCCTGACG
TCGAACGCGGGAAGGCGCTG

Downstream 100 bases:

>100_bases
GCGGAAATGACTTGTGCCACTTACGATGATGGGCCATCCCCATCTCCCGCAAGATACCCATAGCGGCGGGCCAGCCATGC
GTTCGACGCAATCCCCGGAT

Product: putative glycosyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQINTVAAFVRNLTRAQNPLNL
ARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAANVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATM
KVSWRLYAYVSKDADRAQRRELGLPPAPAPAVRRLAERGAPEIQAYDPVFFPGLAAEWSDRRPFVGPLTMELHSEPNEEL
ESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSPAANSTRIRHADHVKRVGLVNYSTILPKCRAVVHH
GGAGTTAAGLRAGMPTLILWDVADQPIWAGAVQRLKVGSAKRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAA
VTAAADLLEATARQTPGSTPSSSPGR

Sequences:

>Translated_426_residues
MKFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQINTVAAFVRNLTRAQNPLNL
ARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAANVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATM
KVSWRLYAYVSKDADRAQRRELGLPPAPAPAVRRLAERGAPEIQAYDPVFFPGLAAEWSDRRPFVGPLTMELHSEPNEEL
ESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSPAANSTRIRHADHVKRVGLVNYSTILPKCRAVVHH
GGAGTTAAGLRAGMPTLILWDVADQPIWAGAVQRLKVGSAKRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAA
VTAAADLLEATARQTPGSTPSSSPGR
>Mature_426_residues
MKFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQINTVAAFVRNLTRAQNPLNL
ARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAANVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATM
KVSWRLYAYVSKDADRAQRRELGLPPAPAPAVRRLAERGAPEIQAYDPVFFPGLAAEWSDRRPFVGPLTMELHSEPNEEL
ESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSPAANSTRIRHADHVKRVGLVNYSTILPKCRAVVHH
GGAGTTAAGLRAGMPTLILWDVADQPIWAGAVQRLKVGSAKRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAA
VTAAADLLEATARQTPGSTPSSSPGR

Specific function: Unknown

COG id: COG1819

COG function: function code GC; Glycosyl transferases, related to UDP-glucuronosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae L518_C2_147 and M.tuberculosis Rv1524

Homologues:

Organism=Saccharomyces cerevisiae, GI6323218, Length=185, Percent_Identity=30.2702702702703, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1526_MYCTU (P64869)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   F70723
- RefSeq:   NP_216042.1
- RefSeq:   NP_336030.1
- ProteinModelPortal:   P64869
- SMR:   P64869
- EnsemblBacteria:   EBMYCT00000003539
- EnsemblBacteria:   EBMYCT00000071720
- GeneID:   886434
- GeneID:   924381
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1577
- KEGG:   mtu:Rv1526c
- TIGR:   MT1577
- TubercuList:   Rv1526c
- GeneTree:   EBGT00050000016234
- HOGENOM:   HBG481731
- OMA:   EDEAACI
- ProtClustDB:   CLSK791224
- InterPro:   IPR004276

Pfam domain/function: PF03033 Glyco_transf_28

EC number: NA

Molecular weight: Translated: 45697; Mature: 45697

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQ
CEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCEEEECCCCCHH
INTVAAFVRNLTRAQNPLNLARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCHHH
NVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATMKVSWRLYAYVSKDADRAQRR
HHHHHHCCCHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHHEEEEEEEECCCHHHHHHH
ELGLPPAPAPAVRRLAERGAPEIQAYDPVFFPGLAAEWSDRRPFVGPLTMELHSEPNEEL
HCCCCCCCCHHHHHHHHCCCCCCEECCCEECCCCCCCCCCCCCCCCCEEEEECCCCHHHH
ESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSPAANSTRIRHADHVK
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHH
RVGLVNYSTILPKCRAVVHHGGAGTTAAGLRAGMPTLILWDVADQPIWAGAVQRLKVGSA
HHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCH
KRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAAVTAAADLLEATARQTPGSTP
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
SSSPGR
CCCCCC
>Mature Secondary Structure
MKFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQ
CEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCEEEECCCCCHH
INTVAAFVRNLTRAQNPLNLARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCHHH
NVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATMKVSWRLYAYVSKDADRAQRR
HHHHHHCCCHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHHEEEEEEEECCCHHHHHHH
ELGLPPAPAPAVRRLAERGAPEIQAYDPVFFPGLAAEWSDRRPFVGPLTMELHSEPNEEL
HCCCCCCCCHHHHHHHHCCCCCCEECCCEECCCCCCCCCCCCCCCCCEEEEECCCCHHHH
ESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSPAANSTRIRHADHVK
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHH
RVGLVNYSTILPKCRAVVHHGGAGTTAAGLRAGMPTLILWDVADQPIWAGAVQRLKVGSA
HHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCH
KRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAAVTAAADLLEATARQTPGSTP
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
SSSPGR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036