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The map label for this gene is pimF

Identifier: 148661295

GI number: 148661295

Start: 1692367

End: 1693395

Strand: Direct

Name: pimF

Synonym: MRA_1511

Alternate gene names: 148661295

Gene position: 1692367-1693395 (Clockwise)

Preceding gene: 148661294

Following gene: 148661296

Centisome position: 38.29

GC content: 54.91

Gene sequence:

>1029_bases
ATGCGCCTCTCGATCGTAACGACTATGTACATGTCAGAGCCTTACGTGCTGGAGTTCTACAGGAGAGCGCGCGCGGCGGC
GGACAAAATCACGCCTGACGTCGAGATCATCTTCGTGGATGACGGCTCGCCGGACGCAGCGCTCCAGCAGGCCGTCTCGC
TGCTCGACAGCGACCCCTGTGTTCGGGTAATTCAGCTTTCGCGAAATTTCGGCCACCACAAAGCGATGATGACCGGCCTG
GCGCACGCCACGGGGGATCTCGTCTTTCTGATCGACTCAGACTTGGAAGAGGACCCGGCTCTCCTAGAGCCGTTCTATGA
AAAGCTGATCTCGACGGGCGCCGACGTAGTATTTGGTTGCCACGCGCGGCGGCCCGGCGGTTGGTTGAGGAATTTCGGAC
CGAAAATCCATTATCGGGCGTCCGCCCTGCTGTGTGACCCCCCGCTTCATGAAAATACTCTCACCGTGCGGCTGATGACA
GCCGACTATGTACGCAGCTTGGTCCAGCACCAGGAGCGTGAACTTTCGATTGCCGGTCTGTGGCAGATTACTGGTTTTTA
CCAGGTGCCCATGTCCGTAAACAAGGCATGGAAAGGAACGACCACATACACGTTTAGGCGTAAAGTAGCGACACTGGTCG
ACAATGTCACTTCATTTAGCAACAAACCTCTAGTCTTCATTTTCTATCTTGGTGCGGCCATTTTTATTATTTCAAGCTCG
GCCGCGGGCTATCTGATCATCGATCGAATTTTCTTTCGCGCTCTGCAAGCGGGGTGGGCATCCGTGATCGTATCCATCTG
GATGCTGGGGGGTGTGACGATTTTCTGCATAGGGCTGGTCGGAATTTATGTATCCAAAGTCTTCATCGAAACTAAGCAGC
GGCCATACACAATTATCCGAAGAATCTACGGTTCGGATTTAACAACCCGGGAGCCATCCTCTCTGAAGACCGCCTTCCCG
GCCGCGCACCTGTCGAACGGGAAACGCGTCACATCAGAGCCAGAGGGATTGGCAACTGGCAACAGGTGA

Upstream 100 bases:

>100_bases
CAACCTGGATCGAACGAGTCCAAAACCGCCGCGGACGCCACTCGGCCCTCGTATGATCCCGAGGAGATACCCTACGGGGT
GGATTGGGGATGGATCGGCG

Downstream 100 bases:

>100_bases
ATAAGCGTAGCATGATTCCTGTAAAGGTTGAAAACAATACTTCGCTCGATCAGGTGCAAGACGCTCTTAATTGCGTCGGG
TACGCGGTTGTAGAAGATGT

Product: putative dolichol-phosphate mannosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRLSIVTTMYMSEPYVLEFYRRARAAADKITPDVEIIFVDDGSPDAALQQAVSLLDSDPCVRVIQLSRNFGHHKAMMTGL
AHATGDLVFLIDSDLEEDPALLEPFYEKLISTGADVVFGCHARRPGGWLRNFGPKIHYRASALLCDPPLHENTLTVRLMT
ADYVRSLVQHQERELSIAGLWQITGFYQVPMSVNKAWKGTTTYTFRRKVATLVDNVTSFSNKPLVFIFYLGAAIFIISSS
AAGYLIIDRIFFRALQAGWASVIVSIWMLGGVTIFCIGLVGIYVSKVFIETKQRPYTIIRRIYGSDLTTREPSSLKTAFP
AAHLSNGKRVTSEPEGLATGNR

Sequences:

>Translated_342_residues
MRLSIVTTMYMSEPYVLEFYRRARAAADKITPDVEIIFVDDGSPDAALQQAVSLLDSDPCVRVIQLSRNFGHHKAMMTGL
AHATGDLVFLIDSDLEEDPALLEPFYEKLISTGADVVFGCHARRPGGWLRNFGPKIHYRASALLCDPPLHENTLTVRLMT
ADYVRSLVQHQERELSIAGLWQITGFYQVPMSVNKAWKGTTTYTFRRKVATLVDNVTSFSNKPLVFIFYLGAAIFIISSS
AAGYLIIDRIFFRALQAGWASVIVSIWMLGGVTIFCIGLVGIYVSKVFIETKQRPYTIIRRIYGSDLTTREPSSLKTAFP
AAHLSNGKRVTSEPEGLATGNR
>Mature_342_residues
MRLSIVTTMYMSEPYVLEFYRRARAAADKITPDVEIIFVDDGSPDAALQQAVSLLDSDPCVRVIQLSRNFGHHKAMMTGL
AHATGDLVFLIDSDLEEDPALLEPFYEKLISTGADVVFGCHARRPGGWLRNFGPKIHYRASALLCDPPLHENTLTVRLMT
ADYVRSLVQHQERELSIAGLWQITGFYQVPMSVNKAWKGTTTYTFRRKVATLVDNVTSFSNKPLVFIFYLGAAIFIISSS
AAGYLIIDRIFFRALQAGWASVIVSIWMLGGVTIFCIGLVGIYVSKVFIETKQRPYTIIRRIYGSDLTTREPSSLKTAFP
AAHLSNGKRVTSEPEGLATGNR

Specific function: May play only a redundant role in maintaining cell wall viability and bacterial virulence

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family

Homologues:

Organism=Escherichia coli, GI1788692, Length=305, Percent_Identity=31.8032786885246, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788588, Length=306, Percent_Identity=26.1437908496732, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLYTR_MYCTU (P71781)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842576
- PIR:   G70712
- RefSeq:   NP_216016.1
- RefSeq:   NP_336001.1
- ProteinModelPortal:   P71781
- SMR:   P71781
- EnsemblBacteria:   EBMYCT00000002302
- EnsemblBacteria:   EBMYCT00000070147
- GeneID:   886492
- GeneID:   924426
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1549
- KEGG:   mtu:Rv1500
- TIGR:   MT1549
- TubercuList:   Rv1500
- GeneTree:   EBGT00050000018350
- HOGENOM:   HBG752660
- OMA:   FNHADYR
- ProtClustDB:   CLSK791202
- InterPro:   IPR001173

Pfam domain/function: PF00535 Glycos_transf_2

EC number: 2.4.1.- [C]

Molecular weight: Translated: 38095; Mature: 38095

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e4f0e18)-; HASH(0x1e207c3c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSIVTTMYMSEPYVLEFYRRARAAADKITPDVEIIFVDDGSPDAALQQAVSLLDSDPC
CEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCH
VRVIQLSRNFGHHKAMMTGLAHATGDLVFLIDSDLEEDPALLEPFYEKLISTGADVVFGC
HHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEE
HARRPGGWLRNFGPKIHYRASALLCDPPLHENTLTVRLMTADYVRSLVQHQERELSIAGL
CCCCCCCHHHHCCCCEEEEEEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEE
WQITGFYQVPMSVNKAWKGTTTYTFRRKVATLVDNVTSFSNKPLVFIFYLGAAIFIISSS
EEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHEECC
AAGYLIIDRIFFRALQAGWASVIVSIWMLGGVTIFCIGLVGIYVSKVFIETKQRPYTIIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RIYGSDLTTREPSSLKTAFPAAHLSNGKRVTSEPEGLATGNR
HHHCCCCCCCCCCHHHHHCCHHHHCCCCEECCCCCCCCCCCH
>Mature Secondary Structure
MRLSIVTTMYMSEPYVLEFYRRARAAADKITPDVEIIFVDDGSPDAALQQAVSLLDSDPC
CEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCH
VRVIQLSRNFGHHKAMMTGLAHATGDLVFLIDSDLEEDPALLEPFYEKLISTGADVVFGC
HHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEE
HARRPGGWLRNFGPKIHYRASALLCDPPLHENTLTVRLMTADYVRSLVQHQERELSIAGL
CCCCCCCHHHHCCCCEEEEEEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEE
WQITGFYQVPMSVNKAWKGTTTYTFRRKVATLVDNVTSFSNKPLVFIFYLGAAIFIISSS
EEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHEECC
AAGYLIIDRIFFRALQAGWASVIVSIWMLGGVTIFCIGLVGIYVSKVFIETKQRPYTIIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RIYGSDLTTREPSSLKTAFPAAHLSNGKRVTSEPEGLATGNR
HHHCCCCCCCCCCHHHHHCCHHHHCCCCEECCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036