Click here to switch to the map view.

The map label for this gene is ampH [C]

Identifier: 148661158

GI number: 148661158

Start: 1540822

End: 1541955

Strand: Reverse

Name: ampH [C]

Synonym: MRA_1377

Alternate gene names: 148661158

Gene position: 1541955-1540822 (Counterclockwise)

Preceding gene: 148661160

Following gene: 148661155

Centisome position: 34.89

GC content: 66.31

Gene sequence:

>1134_bases
ATGGTCTGGCAGCGCGAAAAATTGTTGCAAGTCAACGAGATCGGCTATCGCGATATCGACGCGGGCGTGCCCATGCAACG
CGACACGCTGTTTCGCATCGCGTCGATGACCAAGCCGGTCACGGTGGCGGCGGCGATGAGCCTGGTCGACGAGGGCAAAC
TGGCACTGCGTGACCCGATCACGCGTTGGGCACCGGAGCTCTGCAAGGTGGCCGTGCTGGACGATGCCGCCGGCCCGCTG
GATCGCACACATCCCGCGCGACGAGCCATTTTGATCGAGGACCTGCTCACTCACACCAGCGGCCTGGCTTACGGTTTCTC
GGTGTCGGGGCCAATTTCGCGGGCCTATCAGCGACTGCCGTTCGGCCAGGGTCCCGACGTTTGGCTGGCAGCGCTGGCAA
CCCTTCCGCTCGTGCACCAACCTGGCGACCGGGTGACCTACAGCCACGCCATCGACGTCTTGGGTGTCATTGTCTCCCGC
ATCGAGGACGCACCGCTGTACCAGATCATCGACGAGCGAGTGCTGGGTCCGGCAGGAATGACCGACACCGGCTTCTACGT
GTCGGCCGACGCGCAGCGACGGGCCGCGACCATGTACCGGCTCGACGAACAAGACCGGTTGCGGCACGACGTGATGGGGC
CGCCACACGTCACGCCGCCGTCGTTCTGTAACGCCGGCGGCGGGTTGTGGTCGACCGCCGATGACTACCTGCGGTTCGTG
CGGATGCTGTTGGGCGACGGGACGGTCGACGGGGTCCGGGTGTTGTCACCTGAATCGGTGCGCCTGATGCGCACCGACCG
GCTGACCGACGAGCAGAAACGGCACAGCTTTCTGGGGGCGCCGTTCTGGGTGGGCCGCGGCTTCGGGCTGAACCTATCGG
TGGTGACCGATCCGGCGAAGTCCAGGCCGCTGTTCGGGCCGGGCGGGCTCGGGACCTTCAGCTGGCCCGGCGCGTACGGG
ACATGGTGGCAGGCCGACCCGAGCGCCGACCTGATACTGCTGTATCTGATCCAGCATTGTCCCGATCTGTCCGTGGACGC
TGCCGCGGCCGTCGCGGGTAACCCATCCCTGGCGAAACTGCGGACCGCGCAACCAAAATTCGTCCGCCGCACCTATCGGG
CGCTCGGGCTCTAG

Upstream 100 bases:

>100_bases
CGCTGGCTCGGACAGTATCCTGAACCGGGTGAATCTCGACGGCAATCAGGCGTCCATCCGCGAGGTATGCGACGCGGGCC
TGCTTTCCGGCGCGGTAACC

Downstream 100 bases:

>100_bases
TGCCGGGTAGACATGTTGACCGAACCTCCCCATGTCGACCGGACCCGGCACACTCGCGGAAACCCAAGGGCCTACCGCGC
GCCGTTTCCGACGTTCAGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDAAGPL
DRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSR
IEDAPLYQIIDERVLGPAGMTDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFV
RMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYG
TWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPKFVRRTYRALGL

Sequences:

>Translated_377_residues
MVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDAAGPL
DRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSR
IEDAPLYQIIDERVLGPAGMTDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFV
RMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYG
TWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPKFVRRTYRALGL
>Mature_377_residues
MVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDAAGPL
DRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSR
IEDAPLYQIIDERVLGPAGMTDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFV
RMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYG
TWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPKFVRRTYRALGL

Specific function: Binds Penicillin And Contributes To The Normal Morphology Of Escherichia Coli. [C]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786574, Length=226, Percent_Identity=26.5486725663717, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082101, Length=373, Percent_Identity=25.7372654155496, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1367_MYCTU (Q11037)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   D70957
- RefSeq:   NP_215883.1
- RefSeq:   NP_335863.1
- ProteinModelPortal:   Q11037
- SMR:   Q11037
- EnsemblBacteria:   EBMYCT00000000427
- EnsemblBacteria:   EBMYCT00000071924
- GeneID:   886793
- GeneID:   924581
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1414
- KEGG:   mtu:Rv1367c
- TIGR:   MT1414
- TubercuList:   Rv1367c
- GeneTree:   EBGT00050000015516
- HOGENOM:   HBG734622
- OMA:   YHRFARM
- ProtClustDB:   CLSK871929
- InterPro:   IPR012338
- InterPro:   IPR001466

Pfam domain/function: PF00144 Beta-lactamase; SSF56601 PBP_transp_fold

EC number: NA

Molecular weight: Translated: 41326; Mature: 41326

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPI
CCCCHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCH
TRWAPELCKVAVLDDAAGPLDRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLP
HHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECEECCCHHHHHHHHCC
FGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSRIEDAPLYQIIDERVLGPAGM
CCCCCHHHHHHHHHHCCEECCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
TDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFV
CCCCEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHH
RMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAK
HHHHCCCCCCCEEEECCCCEEEEHHHCCCCHHHHHHHCCCCCEECCCCCCEEEEEECCHH
SRPLFGPGGLGTFSWPGAYGTWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCHHHH
RTAQPKFVRRTYRALGL
HCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPI
CCCCHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCH
TRWAPELCKVAVLDDAAGPLDRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLP
HHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECEECCCHHHHHHHHCC
FGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSRIEDAPLYQIIDERVLGPAGM
CCCCCHHHHHHHHHHCCEECCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
TDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFV
CCCCEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHHHHH
RMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAK
HHHHCCCCCCCEEEECCCCEEEEHHHCCCCHHHHHHHCCCCCEECCCCCCEEEEEECCHH
SRPLFGPGGLGTFSWPGAYGTWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCHHHH
RTAQPKFVRRTYRALGL
HCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036