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The map label for this gene is yciR [C]

Identifier: 148661146

GI number: 148661146

Start: 1526603

End: 1527526

Strand: Reverse

Name: yciR [C]

Synonym: MRA_1365

Alternate gene names: 148661146

Gene position: 1527526-1526603 (Counterclockwise)

Preceding gene: 148661149

Following gene: 148661145

Centisome position: 34.56

GC content: 62.34

Gene sequence:

>924_bases
ATGGATCGTTGTTGTCAGCGCGCTACAGCGTTCGCTTGCGCGCTCAGGCCGACCAAGTTGATCGACTACGAAGAGATGTT
TAGGGGCGCGATGCAAGCGCGAGCGATGGTAGCCAATCCTGACCAATGGGCGGACTCCGACCGCGACCAGGTCAACACTC
GCCATTATCTGTCCACTTCGATGCGCGTGGCACTGGATCGCGGTGAATTCTTCCTCGTCTACCAGCCAATCATCCGGCTT
GCCGACAACCGCATCATCGGCGCCGAGGCCCTGCTGCGCTGGGAACACCCGACGTTGGGCACGCTACTCCCGGGCCGGTT
CATCGACCGTGCCGAGAACAACGGACTGATGGTGCCGCTCACGGCCTTCGTGCTCGAGCAGGCCTGCCGCCACGTCCGCA
GTTGGCGTGACCACAGCACCGACCCGCAACCGTTTGTCAGCGTCAACGTCTCCGCCAGCACCATCTGCGATCCCGGCTTC
CTGGTGCTGGTCGAAGGTGTGCTCGGCGAAACCGGCCTGCCCGCCCATGCCCTGCAGCTCGAACTGGCCGAGGACGCGCG
CCTTAGCAGAGACGAGAAGGCGGTGACCAGGCTACAAGAATTGTCCGCTCTCGGCGTCGGCATCGCCATCGACGACTTCG
GCATTGGATTCTCCAGCCTCGCCTACCTTCCCCGCCTCCCCGTCGACGTGGTCAAACTCGGGGGAAAGTTCATCGAGTGC
CTCGATGGCGACATTCAAGCTCGGCTGGCCAACGAACAGATCACCCGGGCAATGATCGACCTTGGCGACAAGCTCGGTAT
CACCGTCACTGCAAAGCTAGTCGAAACCCCCAGCCAAGCCGCCCGGTTGCGCGCCTTCGGCTGTAAAGCCGCACAAGGCT
GGCACTTTGCCAAGGCACTGCCGGTCGACTTTTTCAGAGAGTAG

Upstream 100 bases:

>100_bases
TGCGACGGTTCGGGTCAAGACGACTTCGGTGGTGTGCTTCGCGTTGCCACCGCGGTCGGCGAGGTGCCCACCGGGCTGTG
AATCCTGATGCAGCCCTTGG

Downstream 100 bases:

>100_bases
GTCGCGTGGGTGTAGATCGATGGCAACGGCGTGTTTCACCAAGCCGTAGAACAGTATGCCCCGCACGCATGAGAGGTGGG
TGGGACCGGTTGAATCGGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRL
ADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGF
LVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE

Sequences:

>Translated_307_residues
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRL
ADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGF
LVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE
>Mature_307_residues
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRL
ADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGF
LVLVEGVLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKALPVDFFRE

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain

Homologues:

Organism=Escherichia coli, GI1787541, Length=250, Percent_Identity=34, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87081921, Length=256, Percent_Identity=33.203125, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790496, Length=256, Percent_Identity=33.203125, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI226510982, Length=289, Percent_Identity=31.1418685121107, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1788502, Length=258, Percent_Identity=31.7829457364341, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=34.2857142857143, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787055, Length=258, Percent_Identity=31.0077519379845, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87081743, Length=249, Percent_Identity=32.1285140562249, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081980, Length=253, Percent_Identity=33.9920948616601, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786507, Length=256, Percent_Identity=28.125, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI87082096, Length=254, Percent_Identity=26.7716535433071, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788849, Length=239, Percent_Identity=28.0334728033473, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787410, Length=229, Percent_Identity=24.4541484716157, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1357_MYCTU (P64829)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   D70741
- RefSeq:   NP_215873.1
- RefSeq:   NP_335849.1
- ProteinModelPortal:   P64829
- SMR:   P64829
- EnsemblBacteria:   EBMYCT00000002544
- EnsemblBacteria:   EBMYCT00000069576
- GeneID:   886815
- GeneID:   924605
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1400
- KEGG:   mtu:Rv1357c
- TIGR:   MT1400
- TubercuList:   Rv1357c
- GeneTree:   EBGT00050000014822
- HOGENOM:   HBG751764
- OMA:   IPENASA
- ProtClustDB:   CLSK791120
- InterPro:   IPR001633
- SMART:   SM00052

Pfam domain/function: PF00563 EAL

EC number: NA

Molecular weight: Translated: 33982; Mature: 33982

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e0927fc)-; HASH(0x1db1c0d0)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCHHHHHHHH
MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL
HEEEEECCCEEEEEHHHHHHHCCCEECHHHHEEECCCCCCCCCCCHHHHHCCCCCEEEHH
TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCHHEEEEHHHCCCCCCHHHEEE
ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
EEHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCHHHHHHCCHHHHH
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCHHHHHHHHHCCCCCCCCCHHHHC
PVDFFRE
CHHHHCH
>Mature Secondary Structure
MDRCCQRATAFACALRPTKLIDYEEMFRGAMQARAMVANPDQWADSDRDQVNTRHYLSTS
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCHHHHHHHH
MRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGRFIDRAENNGLMVPL
HEEEEECCCEEEEEHHHHHHHCCCEECHHHHEEECCCCCCCCCCCHHHHHCCCCCEEEHH
TAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEGVLGETGLPAHALQL
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCHHEEEEHHHCCCCCCHHHEEE
ELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRLPVDVVKLGGKFIEC
EEHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCCHHHHHHCCHHHHH
LDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAFGCKAAQGWHFAKAL
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCHHHHHHHHHCCCCCCCCCHHHHC
PVDFFRE
CHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036