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The map label for this gene is 148661077

Identifier: 148661077

GI number: 148661077

Start: 1444792

End: 1446357

Strand: Reverse

Name: 148661077

Synonym: MRA_1298

Alternate gene names: NA

Gene position: 1446357-1444792 (Counterclockwise)

Preceding gene: 148661079

Following gene: 148661070

Centisome position: 32.72

GC content: 65.33

Gene sequence:

>1566_bases
GTGTTGCAGCGATCACTTGGGGTTAACGGCCGGAAACTCGCCATGAGTGCACGCTCGGCGAAGCGAGAGCGGAAAAATGC
TTCTACTGCCGCATCGAAGTGTTACGTAGTTCCGCCTAGTGCTCGCGGATGGGTGCATGCTTATTCGGTGACCGCAACCA
GCATGCTCAACCGTCGCAAAGCCATACTGGATTACTTACAGGGCGCAGTCTGGGTGCTGCCGACATTCGGCGTTGCGATC
GGTCTGGGGTCGGGAGCGGTCCTGTCGATGATTCCCGTGAAATCCGGCACGCTGATCGACAAGCTGATGTTTCAGGGCAC
CCCAGGCGACGCCCGAGGCGTGCTGATCGTGGTGTCGGCCACGATGATCACCACCATCGGCATCGTCTTCTCGCTGACGG
TGCTGTCCCTACAGATCGCCTCCAGCCAGTTCTCGGTGCGGTTGCTACGAACCTTCCTGCGCGATGTGCCCAACCAGGTG
GTGCTGGCGATCTTTGCCTGCACCTTCGCCTACAGCACCGGTGGGCTACACACCGTCGGGGAGCACCGCGACGGCGGGGC
GTTCATTCCCAAAGTCGCGGTCACCGGGTCACTCGCGCTGGCATTCGTCAGCATCGCCGCGCTGATCTACTTCCTGCACC
ACCTCATGCACTCGATCCAGATAGACACGATCATGGACAAGGTGCGGCTGCGCACGCTGGGGCTGGTTGACCAGTTGTAT
CCGGAATCGGATACGGCGGATCGACAAGTAGAGACACCGCCCAGCCCCCCGGCTGATGCGGTGCCGCTGTTGGCCCCGCA
CTCGGGTTACCTACAAACCGTCGACGTCGACGACATCGCCGAATTGGCGGCAGCCAGCCGGTATACGGCGCTGCTGGTTA
CCTTCGTCGGCGATTACGTCACCGCCGGGGGCCTGCTCGGCTGGTGCTGGCGCAGGGGCACCGCGCCGGGCGCGCCAGGG
TCTGACTTCCCGCAACGCTGCTTACGTCATGTGCACATCGGATTCGAGCGCACCCTGCAGCAGGACATCCGCTTCGGATT
GCGGCAGATGGTGGATATCGCGCTGCGGGCACTATCGCCCGCACTCAACGACCCGTACACGGCGATCCAAGTCGTGCACC
ATCTTTCGGCCGTGGAGTCGGTGCTGGCATCGCGGGCGCTGCCGGACGACGTGCGCCGCGACCGCGCCGGGGAGCTCCTC
TTCTGGCTGCCGTACCCCAGCTTCGCCACCTACCTGCACGTCGGATGTGCCCAGATCCGCCGCTACGGCTCGCGTGAGCC
GCTGGTGCTCACTGCGCTGCTGCAGCTGCTCAGCGCGGTCGCCCAGAACTGCGTCGACCCGTCGCGCCGTGTAGCGGTGC
AAACCCAAATTGCCCTGGTCGTGCGGGCAGCACAGCGCGAGTTCGCGGACGAATCCGACCGGGCCATGGTTCTCGGTGCC
GCGGCGCGGGCGACCGAGGTCGTCGAGCGCCCCGGGACTCTAGCGCCGCCGCCGTCCACGTTCGGCCAGGTAGCCGCCGC
GCAGGCGGCGGCGTCGACGATCCGGTCCGCTGACCGAGACGGCTAG

Upstream 100 bases:

>100_bases
AGCGCCTTCCAGAACTTCCCCTGCACCCCATCGGCCACCCGATCCCCCCGACCCCGAAACCCCTTCTGATAACCCATGCA
GCGCCAACACCTCTGGCCAA

Downstream 100 bases:

>100_bases
CCCGGCGACGATGCACGCCGAAACGGCGGGTTGAGGAGCCGGGCAATCTAACCCAGCCCGGCGGGGCGACAAGCGACCAG
GATTACCCAACTGGCGTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MLQRSLGVNGRKLAMSARSAKRERKNASTAASKCYVVPPSARGWVHAYSVTATSMLNRRKAILDYLQGAVWVLPTFGVAI
GLGSGAVLSMIPVKSGTLIDKLMFQGTPGDARGVLIVVSATMITTIGIVFSLTVLSLQIASSQFSVRLLRTFLRDVPNQV
VLAIFACTFAYSTGGLHTVGEHRDGGAFIPKVAVTGSLALAFVSIAALIYFLHHLMHSIQIDTIMDKVRLRTLGLVDQLY
PESDTADRQVETPPSPPADAVPLLAPHSGYLQTVDVDDIAELAAASRYTALLVTFVGDYVTAGGLLGWCWRRGTAPGAPG
SDFPQRCLRHVHIGFERTLQQDIRFGLRQMVDIALRALSPALNDPYTAIQVVHHLSAVESVLASRALPDDVRRDRAGELL
FWLPYPSFATYLHVGCAQIRRYGSREPLVLTALLQLLSAVAQNCVDPSRRVAVQTQIALVVRAAQREFADESDRAMVLGA
AARATEVVERPGTLAPPPSTFGQVAAAQAAASTIRSADRDG

Sequences:

>Translated_521_residues
MLQRSLGVNGRKLAMSARSAKRERKNASTAASKCYVVPPSARGWVHAYSVTATSMLNRRKAILDYLQGAVWVLPTFGVAI
GLGSGAVLSMIPVKSGTLIDKLMFQGTPGDARGVLIVVSATMITTIGIVFSLTVLSLQIASSQFSVRLLRTFLRDVPNQV
VLAIFACTFAYSTGGLHTVGEHRDGGAFIPKVAVTGSLALAFVSIAALIYFLHHLMHSIQIDTIMDKVRLRTLGLVDQLY
PESDTADRQVETPPSPPADAVPLLAPHSGYLQTVDVDDIAELAAASRYTALLVTFVGDYVTAGGLLGWCWRRGTAPGAPG
SDFPQRCLRHVHIGFERTLQQDIRFGLRQMVDIALRALSPALNDPYTAIQVVHHLSAVESVLASRALPDDVRRDRAGELL
FWLPYPSFATYLHVGCAQIRRYGSREPLVLTALLQLLSAVAQNCVDPSRRVAVQTQIALVVRAAQREFADESDRAMVLGA
AARATEVVERPGTLAPPPSTFGQVAAAQAAASTIRSADRDG
>Mature_521_residues
MLQRSLGVNGRKLAMSARSAKRERKNASTAASKCYVVPPSARGWVHAYSVTATSMLNRRKAILDYLQGAVWVLPTFGVAI
GLGSGAVLSMIPVKSGTLIDKLMFQGTPGDARGVLIVVSATMITTIGIVFSLTVLSLQIASSQFSVRLLRTFLRDVPNQV
VLAIFACTFAYSTGGLHTVGEHRDGGAFIPKVAVTGSLALAFVSIAALIYFLHHLMHSIQIDTIMDKVRLRTLGLVDQLY
PESDTADRQVETPPSPPADAVPLLAPHSGYLQTVDVDDIAELAAASRYTALLVTFVGDYVTAGGLLGWCWRRGTAPGAPG
SDFPQRCLRHVHIGFERTLQQDIRFGLRQMVDIALRALSPALNDPYTAIQVVHHLSAVESVLASRALPDDVRRDRAGELL
FWLPYPSFATYLHVGCAQIRRYGSREPLVLTALLQLLSAVAQNCVDPSRRVAVQTQIALVVRAAQREFADESDRAMVLGA
AARATEVVERPGTLAPPPSTFGQVAAAQAAASTIRSADRDG

Specific function: Unknown

COG id: COG4325

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1290_MYCTU (P0A5E3)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   F70772
- RefSeq:   NP_215806.1
- RefSeq:   NP_335775.1
- EnsemblBacteria:   EBMYCT00000003263
- EnsemblBacteria:   EBMYCT00000070342
- GeneID:   886971
- GeneID:   924734
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1328
- KEGG:   mtu:Rv1290c
- TIGR:   MT1328
- TubercuList:   Rv1290c
- GeneTree:   EBGT00050000018329
- HOGENOM:   HBG565137
- OMA:   GYLQAID
- ProtClustDB:   CLSK791084
- GO:   GO:0005829
- GO:   GO:0009405
- InterPro:   IPR018723

Pfam domain/function: PF10011 DUF2254

EC number: NA

Molecular weight: Translated: 56028; Mature: 56028

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d3da16c)-; HASH(0x1d5b9854)-; HASH(0x1ae5d56c)-; HASH(0x1d88eec8)-; HASH(0x1dea8850)-; HASH(0x1c7cd054)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRSLGVNGRKLAMSARSAKRERKNASTAASKCYVVPPSARGWVHAYSVTATSMLNRRK
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCEEEEHHHHHHHHHHHH
AILDYLQGAVWVLPTFGVAIGLGSGAVLSMIPVKSGTLIDKLMFQGTPGDARGVLIVVSA
HHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEHH
TMITTIGIVFSLTVLSLQIASSQFSVRLLRTFLRDVPNQVVLAIFACTFAYSTGGLHTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
EHRDGGAFIPKVAVTGSLALAFVSIAALIYFLHHLMHSIQIDTIMDKVRLRTLGLVDQLY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PESDTADRQVETPPSPPADAVPLLAPHSGYLQTVDVDDIAELAAASRYTALLVTFVGDYV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
TAGGLLGWCWRRGTAPGAPGSDFPQRCLRHVHIGFERTLQQDIRFGLRQMVDIALRALSP
HHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
ALNDPYTAIQVVHHLSAVESVLASRALPDDVRRDRAGELLFWLPYPSFATYLHVGCAQIR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RYGSREPLVLTALLQLLSAVAQNCVDPSRRVAVQTQIALVVRAAQREFADESDRAMVLGA
HCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEH
AARATEVVERPGTLAPPPSTFGQVAAAQAAASTIRSADRDG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MLQRSLGVNGRKLAMSARSAKRERKNASTAASKCYVVPPSARGWVHAYSVTATSMLNRRK
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCEEEEHHHHHHHHHHHH
AILDYLQGAVWVLPTFGVAIGLGSGAVLSMIPVKSGTLIDKLMFQGTPGDARGVLIVVSA
HHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEHH
TMITTIGIVFSLTVLSLQIASSQFSVRLLRTFLRDVPNQVVLAIFACTFAYSTGGLHTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
EHRDGGAFIPKVAVTGSLALAFVSIAALIYFLHHLMHSIQIDTIMDKVRLRTLGLVDQLY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PESDTADRQVETPPSPPADAVPLLAPHSGYLQTVDVDDIAELAAASRYTALLVTFVGDYV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
TAGGLLGWCWRRGTAPGAPGSDFPQRCLRHVHIGFERTLQQDIRFGLRQMVDIALRALSP
HHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
ALNDPYTAIQVVHHLSAVESVLASRALPDDVRRDRAGELLFWLPYPSFATYLHVGCAQIR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RYGSREPLVLTALLQLLSAVAQNCVDPSRRVAVQTQIALVVRAAQREFADESDRAMVLGA
HCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEH
AARATEVVERPGTLAPPPSTFGQVAAAQAAASTIRSADRDG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036