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The map label for this gene is corA [H]

Identifier: 148661026

GI number: 148661026

Start: 1383252

End: 1384352

Strand: Reverse

Name: corA [H]

Synonym: MRA_1248

Alternate gene names: 148661026

Gene position: 1384352-1383252 (Counterclockwise)

Preceding gene: 148661030

Following gene: 148661020

Centisome position: 31.32

GC content: 62.13

Gene sequence:

>1101_bases
GTGTTCCCAGGGTTTGACGCATTGCCCGAAGTGCTGCGACCGGTCGCGCGACCCCAGCCGCCGAACGCACACCCCGTTGC
CCAGCCACCGGCCCAAGCCTTGGTCGACTGCGGTGTCTACGTCTGCGGCCAGCGACTGCCCGGCAAGTACACCTACGCCG
CCGCGCTGCGCGAGGTGCGCGAGATCGAACTGACCGGGCAGGAGGCGTTCGTCTGGATCGGGCTGCACGAGCCCGATGAA
AACCAGATGCAGGACGTAGCAGACGTTTTCGGGTTGCACCCGTTAGCCGTTGAGGACGCCGTGCACGCGCACCAGCGACC
CAAGTTGGAGCGCTACGACGAGACGCTGTTCCTCGTCCTCAAGACCGTCAACTACGTCCCGCACGAATCGGTGGTACTGG
CCCGCGAGATCGTCAAAACCGGCGAGATCATGATCTTCGTCGGCAAGGATTTCGTGGTCACCGTCCGCCACGGCGAACAC
GGCGGGTTATCCGAGGTGCGTAAGCGGATGGATGCCGACCCCGAACATTTGCGGTTGGGACCGTATGCGGTGATGCACGC
GATCGCCGACTACGTGGTCGACCACTACCTCGAGGTGACCAATCTCATGGAGACCGATATCGACAGCATCGAGGAAGTAG
CGTTCGCGCCGGGCCGCAAGCTCGACATCGAACCGATCTATCTGCTCAAGCGGGAAGTGGTCGAGTTGCGCCGGTGCGTG
AATCCGCTATCGACCGCATTCCAGCGCATGCAGACCGAGAGCAAAGACCTCATTTCGAAAGAAGTGCGGCGCTACCTGCG
CGACGTCGCCGACCACCAGACCGAGGCCGCCGACCAGATCGCCAGCTACGACGACATGCTCAACTCGCTGGTGCAGGCCG
CGCTCGCCCGGGTCGGCATGCAGCAAAACATGGACATGCGCAAGATATCCGCGTGGGCAGGTATCATCGCGGTCCCCACC
ATGATCGCGGGCATCTATGGCATGAACTTTCACTTCATGCCCGAGCTGGACTCCAGGTGGGGTTACCCGACAGTGATCGG
CGGGATGGTCCTTATCTGTCTGTTCCTCTACCACGTCTTCCGCAACAGAAACTGGCTCTAG

Upstream 100 bases:

>100_bases
GTCCAACCCCCACAGCTACGACTGACGTTTACCAAGTTCCATACCGGGACGCGTAACCTGGAGCACCGCCCGATCAGATC
CACCGCGATCGGAGGTTGAC

Downstream 100 bases:

>100_bases
CTTCGCGTCGGCGAACAGACGCAAAAAGCTCCAAATCCTTCGGCGTGGCGGGGGCTTATGTGTCCGCTCGCCGCCATTAG
GCGCGGTGCGGAATGGTCAG

Product: CorA family transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MFPGFDALPEVLRPVARPQPPNAHPVAQPPAQALVDCGVYVCGQRLPGKYTYAAALREVREIELTGQEAFVWIGLHEPDE
NQMQDVADVFGLHPLAVEDAVHAHQRPKLERYDETLFLVLKTVNYVPHESVVLAREIVKTGEIMIFVGKDFVVTVRHGEH
GGLSEVRKRMDADPEHLRLGPYAVMHAIADYVVDHYLEVTNLMETDIDSIEEVAFAPGRKLDIEPIYLLKREVVELRRCV
NPLSTAFQRMQTESKDLISKEVRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGMQQNMDMRKISAWAGIIAVPT
MIAGIYGMNFHFMPELDSRWGYPTVIGGMVLICLFLYHVFRNRNWL

Sequences:

>Translated_366_residues
MFPGFDALPEVLRPVARPQPPNAHPVAQPPAQALVDCGVYVCGQRLPGKYTYAAALREVREIELTGQEAFVWIGLHEPDE
NQMQDVADVFGLHPLAVEDAVHAHQRPKLERYDETLFLVLKTVNYVPHESVVLAREIVKTGEIMIFVGKDFVVTVRHGEH
GGLSEVRKRMDADPEHLRLGPYAVMHAIADYVVDHYLEVTNLMETDIDSIEEVAFAPGRKLDIEPIYLLKREVVELRRCV
NPLSTAFQRMQTESKDLISKEVRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGMQQNMDMRKISAWAGIIAVPT
MIAGIYGMNFHFMPELDSRWGYPTVIGGMVLICLFLYHVFRNRNWL
>Mature_366_residues
MFPGFDALPEVLRPVARPQPPNAHPVAQPPAQALVDCGVYVCGQRLPGKYTYAAALREVREIELTGQEAFVWIGLHEPDE
NQMQDVADVFGLHPLAVEDAVHAHQRPKLERYDETLFLVLKTVNYVPHESVVLAREIVKTGEIMIFVGKDFVVTVRHGEH
GGLSEVRKRMDADPEHLRLGPYAVMHAIADYVVDHYLEVTNLMETDIDSIEEVAFAPGRKLDIEPIYLLKREVVELRRCV
NPLSTAFQRMQTESKDLISKEVRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGMQQNMDMRKISAWAGIIAVPT
MIAGIYGMNFHFMPELDSRWGYPTVIGGMVLICLFLYHVFRNRNWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=80, Percent_Identity=41.25, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41501; Mature: 41501

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPGFDALPEVLRPVARPQPPNAHPVAQPPAQALVDCGVYVCGQRLPGKYTYAAALREVR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EIELTGQEAFVWIGLHEPDENQMQDVADVFGLHPLAVEDAVHAHQRPKLERYDETLFLVL
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
KTVNYVPHESVVLAREIVKTGEIMIFVGKDFVVTVRHGEHGGLSEVRKRMDADPEHLRLG
HHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCHHHHHHHHCCCHHHHCCC
PYAVMHAIADYVVDHYLEVTNLMETDIDSIEEVAFAPGRKLDIEPIYLLKREVVELRRCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
NPLSTAFQRMQTESKDLISKEVRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQNMDMRKISAWAGIIAVPTMIAGIYGMNFHFMPELDSRWGYPTVIGGMVLICLFLYHVF
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
RNRNWL
HCCCCC
>Mature Secondary Structure
MFPGFDALPEVLRPVARPQPPNAHPVAQPPAQALVDCGVYVCGQRLPGKYTYAAALREVR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EIELTGQEAFVWIGLHEPDENQMQDVADVFGLHPLAVEDAVHAHQRPKLERYDETLFLVL
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
KTVNYVPHESVVLAREIVKTGEIMIFVGKDFVVTVRHGEHGGLSEVRKRMDADPEHLRLG
HHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCHHHHHHHHCCCHHHHCCC
PYAVMHAIADYVVDHYLEVTNLMETDIDSIEEVAFAPGRKLDIEPIYLLKREVVELRRCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
NPLSTAFQRMQTESKDLISKEVRRYLRDVADHQTEAADQIASYDDMLNSLVQAALARVGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQNMDMRKISAWAGIIAVPTMIAGIYGMNFHFMPELDSRWGYPTVIGGMVLICLFLYHVF
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
RNRNWL
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]