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The map label for this gene is fadH [H]

Identifier: 148660963

GI number: 148660963

Start: 1307512

End: 1309536

Strand: Reverse

Name: fadH [H]

Synonym: MRA_1186

Alternate gene names: 148660963

Gene position: 1309536-1307512 (Counterclockwise)

Preceding gene: 148660964

Following gene: 148660962

Centisome position: 29.63

GC content: 65.23

Gene sequence:

>2025_bases
ATGACAAATCCATACCCAAATCTGCTGTCCCCGTTGGACCTTGGGTTTACCACGCTGCGCAACCGGGTGGTTATGGGTTC
GATGCACACCGGACTGGAAGACCGGGCCCGCCATATCGATCGGCTCGCCGACTACTTCGCCGAACGTGCACGCGGCGGCG
TCGGGCTGATCATCACCGGTGGCTACGCGCCCAACCGCACCGGATGGCTGCTGCCGTTCGCCTCCGAACTCGTCACTTCG
GCGCAAGCCCGACGGCACCGCCGAATCACCAGGGCGGTCCACGATTCGGGTGCAAAGATCCTGCTGCAAATCCTGCACGC
CGGACGCTACGCCTACCACCCACTTGCGGTCAGCGCCTCGCCGATCAAGGCGCCGATCACCCCGTTTCGTCCGCGAGCAC
TATCGGCTCGCGGGGTCGAAGCGACCATCGCGGATTTCGCCCGCTGCGCGCAGTTGGCCCGCGATGCCGGCTACGACGGC
GTCGAAATCATGGGCAGCGAAGGGTATCTGCTCAATCAGTTCCTGGCGCCGCGCACCAACAAGCGCACCGACTCGTGGGG
CGGCACACCGGCCAACCGTCGCCGGTTCCCGGTCGAGATCATCCGACGCAGCCGCGCCGCCGTCGGATGCGACTTCATCA
TCTGTTACCGGCTGTCAATGGCCGACTACGTTGCAGAAGGCCAGAGTTGGGATGAAATCGTCGCGCTGGCAACCGAAGTG
GAAGGGGCAGGCGCAACCATCATCAACTCCGGCTTCGGCTGGCACGAGGCCCGGGTGCCCACTATCGTCACCTCAGTGCC
GGGCGGCGCGTTTGTCGACATCAGCAGCGCCGTCGCCGAACACGTCACTATCCCGGTGGTGGCGTCCAACCGGATCAACA
TGCCGCAGGCCGCGGAACGGATTCTGGCCGAAACCCAGGTGCGGCTGATATCAATGGCCCGGCCGATGCTGAGCGACCCG
GACTGGGTGCTCAAGGCGCAGTCCAATCGGGTCGACGAAATCAACACCTGCATCTCCTGCAATCAAGCCTGCCTGGACCA
CGCATTTGCCAGGAAAACGGTGTCGTGTCTGCTCAATCCACGCGCCGGGCGCGAGACGCAGTTGGTGCTGTCCCCGACCC
GGCGCGCCCGCTCGGTGGCCGTCGTCGGGGCTGGACCAGCCGGGCTGGCCACGGCGGCCAACGCCGCGCAACGGGGTCAC
CGGGTCACGCTGTTCGAGGCCAACGACTTTATCGGTGGACAGTTTGACATGGCCCGCCGCATTCCCGGCAAAGAGGAATT
CAGCGAAACCATCCGGTATTTCTCGACGATTCTGGCCAAACACGGTGTCGAGGTGCGACTGGGCACTCGGGTGGCCGCCC
AGGAGTTGACCGGCTACGACGAGGTCGTCTTGGCCACCGGCGTGGCACCGCGCATTCCGGCCATCCCCGGCATCGACCAC
CCCATGGTGTTAACCTACGCCGAAGCCATCACCGGTGTCAGACCGGTCGGGCGAACCGTGGCTGTCGTCGGCGCCGGCGG
CATTGGCTTCGACGTCACCGAACTGCTGGTCACCGACTCCTCACCCACCCTCAACCTCAAAGAGTGGAAGGCCGAATGGG
GGGTCGCTGATCCGCGAGAAGCCCGCGGAGCGTTGACGACTCCACTGCCGGCGCCGCCCGCCCGTGAGGTGTACCTACTG
CAGCGCACCAAAGGCCCGCAGGGCAAGCGGCTCGGCAAGACCACCGGATGGGTCCACCGGGCGTCGTTGAAGGCCAAGGG
CGTTCATCAGCTGTCTGGGGTGAACTACGAACAGATCAACGACGACGGCCTACACATCAGCTTCGGCCCGAAGCGCAGGC
GGCCCCAGCTGCTGGCGGTGGACAACGTAGTGGTCTGCGCCGGCCAGGAACCGGTGCGAGATCTGGAGAGTGAACTGCGC
CGGCACGGCATTAACCCGCACATCATCGGTGGCGCGGCGGTTGCCGCTGAGTTGGACGCCAAGCGCGCCATCAAGCAAGG
CACCGAACTTGCGGCCAGGCTATAA

Upstream 100 bases:

>100_bases
CCGCACTGCATCAATACCTCGTGCTGCGCGGCGGAATCCGAGCCGAAGAAAGTGCCATCGATTGGCTCGACGAAGTAGCT
GAAGCGCTCCAGGAGAAGCG

Downstream 100 bases:

>100_bases
ACTCATTTCTCGGGCTGTAAACAACGTTGTTTCATCGCTGCTGACCTGCAGATTGGTATGGCCGCGCAGTGTCGCCCGAT
AACCAGTTTGAGAGAAGCAA

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MTNPYPNLLSPLDLGFTTLRNRVVMGSMHTGLEDRARHIDRLADYFAERARGGVGLIITGGYAPNRTGWLLPFASELVTS
AQARRHRRITRAVHDSGAKILLQILHAGRYAYHPLAVSASPIKAPITPFRPRALSARGVEATIADFARCAQLARDAGYDG
VEIMGSEGYLLNQFLAPRTNKRTDSWGGTPANRRRFPVEIIRRSRAAVGCDFIICYRLSMADYVAEGQSWDEIVALATEV
EGAGATIINSGFGWHEARVPTIVTSVPGGAFVDISSAVAEHVTIPVVASNRINMPQAAERILAETQVRLISMARPMLSDP
DWVLKAQSNRVDEINTCISCNQACLDHAFARKTVSCLLNPRAGRETQLVLSPTRRARSVAVVGAGPAGLATAANAAQRGH
RVTLFEANDFIGGQFDMARRIPGKEEFSETIRYFSTILAKHGVEVRLGTRVAAQELTGYDEVVLATGVAPRIPAIPGIDH
PMVLTYAEAITGVRPVGRTVAVVGAGGIGFDVTELLVTDSSPTLNLKEWKAEWGVADPREARGALTTPLPAPPAREVYLL
QRTKGPQGKRLGKTTGWVHRASLKAKGVHQLSGVNYEQINDDGLHISFGPKRRRPQLLAVDNVVVCAGQEPVRDLESELR
RHGINPHIIGGAAVAAELDAKRAIKQGTELAARL

Sequences:

>Translated_674_residues
MTNPYPNLLSPLDLGFTTLRNRVVMGSMHTGLEDRARHIDRLADYFAERARGGVGLIITGGYAPNRTGWLLPFASELVTS
AQARRHRRITRAVHDSGAKILLQILHAGRYAYHPLAVSASPIKAPITPFRPRALSARGVEATIADFARCAQLARDAGYDG
VEIMGSEGYLLNQFLAPRTNKRTDSWGGTPANRRRFPVEIIRRSRAAVGCDFIICYRLSMADYVAEGQSWDEIVALATEV
EGAGATIINSGFGWHEARVPTIVTSVPGGAFVDISSAVAEHVTIPVVASNRINMPQAAERILAETQVRLISMARPMLSDP
DWVLKAQSNRVDEINTCISCNQACLDHAFARKTVSCLLNPRAGRETQLVLSPTRRARSVAVVGAGPAGLATAANAAQRGH
RVTLFEANDFIGGQFDMARRIPGKEEFSETIRYFSTILAKHGVEVRLGTRVAAQELTGYDEVVLATGVAPRIPAIPGIDH
PMVLTYAEAITGVRPVGRTVAVVGAGGIGFDVTELLVTDSSPTLNLKEWKAEWGVADPREARGALTTPLPAPPAREVYLL
QRTKGPQGKRLGKTTGWVHRASLKAKGVHQLSGVNYEQINDDGLHISFGPKRRRPQLLAVDNVVVCAGQEPVRDLESELR
RHGINPHIIGGAAVAAELDAKRAIKQGTELAARL
>Mature_673_residues
TNPYPNLLSPLDLGFTTLRNRVVMGSMHTGLEDRARHIDRLADYFAERARGGVGLIITGGYAPNRTGWLLPFASELVTSA
QARRHRRITRAVHDSGAKILLQILHAGRYAYHPLAVSASPIKAPITPFRPRALSARGVEATIADFARCAQLARDAGYDGV
EIMGSEGYLLNQFLAPRTNKRTDSWGGTPANRRRFPVEIIRRSRAAVGCDFIICYRLSMADYVAEGQSWDEIVALATEVE
GAGATIINSGFGWHEARVPTIVTSVPGGAFVDISSAVAEHVTIPVVASNRINMPQAAERILAETQVRLISMARPMLSDPD
WVLKAQSNRVDEINTCISCNQACLDHAFARKTVSCLLNPRAGRETQLVLSPTRRARSVAVVGAGPAGLATAANAAQRGHR
VTLFEANDFIGGQFDMARRIPGKEEFSETIRYFSTILAKHGVEVRLGTRVAAQELTGYDEVVLATGVAPRIPAIPGIDHP
MVLTYAEAITGVRPVGRTVAVVGAGGIGFDVTELLVTDSSPTLNLKEWKAEWGVADPREARGALTTPLPAPPAREVYLLQ
RTKGPQGKRLGKTTGWVHRASLKAKGVHQLSGVNYEQINDDGLHISFGPKRRRPQLLAVDNVVVCAGQEPVRDLESELRR
HGINPHIIGGAAVAAELDAKRAIKQGTELAARL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=674, Percent_Identity=52.8189910979229, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=237, Percent_Identity=28.6919831223629, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=234, Percent_Identity=28.2051282051282, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=226, Percent_Identity=26.9911504424779, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=352, Percent_Identity=22.4431818181818, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17565138, Length=222, Percent_Identity=26.5765765765766, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559802, Length=179, Percent_Identity=30.7262569832402, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17566914, Length=281, Percent_Identity=27.0462633451957, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72001454, Length=236, Percent_Identity=26.6949152542373, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=220, Percent_Identity=29.5454545454545, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321973, Length=228, Percent_Identity=28.0701754385965, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28574881, Length=192, Percent_Identity=30.2083333333333, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24665539, Length=192, Percent_Identity=30.2083333333333, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72902; Mature: 72771

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPYPNLLSPLDLGFTTLRNRVVMGSMHTGLEDRARHIDRLADYFAERARGGVGLIITG
CCCCCCCCCCHHHHHHHHHHCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GYAPNRTGWLLPFASELVTSAQARRHRRITRAVHDSGAKILLQILHAGRYAYHPLAVSAS
CCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEECCEEECCC
PIKAPITPFRPRALSARGVEATIADFARCAQLARDAGYDGVEIMGSEGYLLNQFLAPRTN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCC
KRTDSWGGTPANRRRFPVEIIRRSRAAVGCDFIICYRLSMADYVAEGQSWDEIVALATEV
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHC
EGAGATIINSGFGWHEARVPTIVTSVPGGAFVDISSAVAEHVTIPVVASNRINMPQAAER
CCCCCEEEECCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHEEEEEEECCCCCCHHHHHH
ILAETQVRLISMARPMLSDPDWVLKAQSNRVDEINTCISCNQACLDHAFARKTVSCLLNP
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
RAGRETQLVLSPTRRARSVAVVGAGPAGLATAANAAQRGHRVTLFEANDFIGGQFDMARR
CCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHC
IPGKEEFSETIRYFSTILAKHGVEVRLGTRVAAQELTGYDEVVLATGVAPRIPAIPGIDH
CCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCC
PMVLTYAEAITGVRPVGRTVAVVGAGGIGFDVTELLVTDSSPTLNLKEWKAEWGVADPRE
CHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHH
ARGALTTPLPAPPAREVYLLQRTKGPQGKRLGKTTGWVHRASLKAKGVHQLSGVNYEQIN
HCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCHHHCC
DDGLHISFGPKRRRPQLLAVDNVVVCAGQEPVRDLESELRRHGINPHIIGGAAVAAELDA
CCCEEEEECCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHH
KRAIKQGTELAARL
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TNPYPNLLSPLDLGFTTLRNRVVMGSMHTGLEDRARHIDRLADYFAERARGGVGLIITG
CCCCCCCCCHHHHHHHHHHCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GYAPNRTGWLLPFASELVTSAQARRHRRITRAVHDSGAKILLQILHAGRYAYHPLAVSAS
CCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEECCEEECCC
PIKAPITPFRPRALSARGVEATIADFARCAQLARDAGYDGVEIMGSEGYLLNQFLAPRTN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCC
KRTDSWGGTPANRRRFPVEIIRRSRAAVGCDFIICYRLSMADYVAEGQSWDEIVALATEV
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHC
EGAGATIINSGFGWHEARVPTIVTSVPGGAFVDISSAVAEHVTIPVVASNRINMPQAAER
CCCCCEEEECCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHEEEEEEECCCCCCHHHHHH
ILAETQVRLISMARPMLSDPDWVLKAQSNRVDEINTCISCNQACLDHAFARKTVSCLLNP
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
RAGRETQLVLSPTRRARSVAVVGAGPAGLATAANAAQRGHRVTLFEANDFIGGQFDMARR
CCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHC
IPGKEEFSETIRYFSTILAKHGVEVRLGTRVAAQELTGYDEVVLATGVAPRIPAIPGIDH
CCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCC
PMVLTYAEAITGVRPVGRTVAVVGAGGIGFDVTELLVTDSSPTLNLKEWKAEWGVADPRE
CHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHH
ARGALTTPLPAPPAREVYLLQRTKGPQGKRLGKTTGWVHRASLKAKGVHQLSGVNYEQIN
HCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCHHHCC
DDGLHISFGPKRRRPQLLAVDNVVVCAGQEPVRDLESELRRHGINPHIIGGAAVAAELDA
CCCEEEEECCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHH
KRAIKQGTELAARL
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]