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The map label for this gene is ephC [H]

Identifier: 148660910

GI number: 148660910

Start: 1248437

End: 1249387

Strand: Direct

Name: ephC [H]

Synonym: MRA_1133

Alternate gene names: 148660910

Gene position: 1248437-1249387 (Clockwise)

Preceding gene: 148660908

Following gene: 148660911

Centisome position: 28.25

GC content: 67.82

Gene sequence:

>951_bases
ATGCGGGCTGGACGCGGCGAACGGGAGTCAACATGGCGGACGACAATGGCTGAACCACACTGGATTGACGTGAAGGGTCC
CAACGGCGACCTGAAAGCCTTGACCTGGGGGCCGGCCGGCGCGCCAGTTGCGTTGTGCTTGCACGGCTTTCCGGATACCG
CCTACGGGTGGCGCAAGGTCGCACCCCGGCTGGCCGAGTCCGGCTGGCACGTCGTGGCGCCGTTCATGCGTGGTTATGCG
CCGTCTTCGATTCCGGCCGACGGCAGCTATCACGTCGGTGCGTTGATGCACGACGCCCTGCGGGTGCGCTCGGCTGCCGG
TGGCACCGAGCGCGATGTGATCATCGGCCACGACTGGGGCGCGATCGCCGCTACCGGCCTGGCCGCCATGCCCGACAGCC
CGTTTGCCAAGGCGGTGATCATGTCGGTGCCGCCGTCGGCGGCATTTCGCCCGCTGGGCCGGGTGCCCGAGCGTGGCCGG
TTGCTGCGTGAGTTGCCGCATCAGCTGCTGCGCAGCTGGTACATCCTGTACTTCCAGTTGCCCTGGCTGCCGGAGCGATC
CGCCTCCTGGGTGGTGCCGCTGCTGTGGCGGCGTTGGTCGCCGGGCTATCACGCCGAGGAAGACCTGCGGCATGTCGACG
CCGCGATCGGGACGCCGGAGGGCCGGCGGGCGGCCTTGGGACCGTATCGCGCCACCATGCGCAACACCCGGGCCCCGGCG
GACTATGCCGACTTGAATCGGCTGTGGACCGAGGCGCCGAAGCTGCCGGTTCTGTACCTGCATGGCCACGACGATGGCTG
TGCCACATCGGCATTCACTCATTGGACGGCAAGGGTGTTGCCCGCCGGCAGTGAGGTGGCCGTAGTGGAACACGCCGGGC
ACTTCTTGCAGCTCGAGCAGCCGGACAAGATTGCAGAGTTGATCGTGGCGTTCATTGGCTCACCCGGCTGA

Upstream 100 bases:

>100_bases
TTGCTGGGCACGCGCCAAATCGTCATCGCCGACCTGGAGGATGCGGTGATCAAGGTGCCCTAGCTACTGGCCTCTTGGGT
TCCGCCGGTTACGTTGGACC

Downstream 100 bases:

>100_bases
AGTCGTGGCCGGGCACCGGATGGCGGCCGTCGACGCGCAGTTCTACTGGATGTCGGCCAAAGTCCCCAACGACCAGTTCC
TGCTGTATGCGTTCGATGGT

Product: putative epoxide hydrolase EphC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRAGRGERESTWRTTMAEPHWIDVKGPNGDLKALTWGPAGAPVALCLHGFPDTAYGWRKVAPRLAESGWHVVAPFMRGYA
PSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWGAIAATGLAAMPDSPFAKAVIMSVPPSAAFRPLGRVPERGR
LLRELPHQLLRSWYILYFQLPWLPERSASWVVPLLWRRWSPGYHAEEDLRHVDAAIGTPEGRRAALGPYRATMRNTRAPA
DYADLNRLWTEAPKLPVLYLHGHDDGCATSAFTHWTARVLPAGSEVAVVEHAGHFLQLEQPDKIAELIVAFIGSPG

Sequences:

>Translated_316_residues
MRAGRGERESTWRTTMAEPHWIDVKGPNGDLKALTWGPAGAPVALCLHGFPDTAYGWRKVAPRLAESGWHVVAPFMRGYA
PSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWGAIAATGLAAMPDSPFAKAVIMSVPPSAAFRPLGRVPERGR
LLRELPHQLLRSWYILYFQLPWLPERSASWVVPLLWRRWSPGYHAEEDLRHVDAAIGTPEGRRAALGPYRATMRNTRAPA
DYADLNRLWTEAPKLPVLYLHGHDDGCATSAFTHWTARVLPAGSEVAVVEHAGHFLQLEQPDKIAELIVAFIGSPG
>Mature_316_residues
MRAGRGERESTWRTTMAEPHWIDVKGPNGDLKALTWGPAGAPVALCLHGFPDTAYGWRKVAPRLAESGWHVVAPFMRGYA
PSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWGAIAATGLAAMPDSPFAKAVIMSVPPSAAFRPLGRVPERGR
LLRELPHQLLRSWYILYFQLPWLPERSASWVVPLLWRRWSPGYHAEEDLRHVDAAIGTPEGRRAALGPYRATMRNTRAPA
DYADLNRLWTEAPKLPVLYLHGHDDGCATSAFTHWTARVLPAGSEVAVVEHAGHFLQLEQPDKIAELIVAFIGSPG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=303, Percent_Identity=26.4026402640264, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI218777840, Length=307, Percent_Identity=25.4071661237785, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI13376164, Length=307, Percent_Identity=25.4071661237785, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562298, Length=301, Percent_Identity=24.9169435215947, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34695; Mature: 34695

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGRGERESTWRTTMAEPHWIDVKGPNGDLKALTWGPAGAPVALCLHGFPDTAYGWRKV
CCCCCCCCCCHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHH
APRLAESGWHVVAPFMRGYAPSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWG
HHHHHHCCCEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
AIAATGLAAMPDSPFAKAVIMSVPPSAAFRPLGRVPERGRLLRELPHQLLRSWYILYFQL
HHHHHCHHCCCCCCCHHEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEC
PWLPERSASWVVPLLWRRWSPGYHAEEDLRHVDAAIGTPEGRRAALGPYRATMRNTRAPA
CCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCC
DYADLNRLWTEAPKLPVLYLHGHDDGCATSAFTHWTARVLPAGSEVAVVEHAGHFLQLEQ
CHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHEEECCCCCEEEEECCCCEEEECC
PDKIAELIVAFIGSPG
CHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRAGRGERESTWRTTMAEPHWIDVKGPNGDLKALTWGPAGAPVALCLHGFPDTAYGWRKV
CCCCCCCCCCHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHH
APRLAESGWHVVAPFMRGYAPSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWG
HHHHHHCCCEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
AIAATGLAAMPDSPFAKAVIMSVPPSAAFRPLGRVPERGRLLRELPHQLLRSWYILYFQL
HHHHHCHHCCCCCCCHHEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEC
PWLPERSASWVVPLLWRRWSPGYHAEEDLRHVDAAIGTPEGRRAALGPYRATMRNTRAPA
CCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCC
DYADLNRLWTEAPKLPVLYLHGHDDGCATSAFTHWTARVLPAGSEVAVVEHAGHFLQLEQ
CHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHEEECCCCCEEEEECCCCEEEECC
PDKIAELIVAFIGSPG
CHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]