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The map label for this gene is 148660651

Identifier: 148660651

GI number: 148660651

Start: 973852

End: 975012

Strand: Reverse

Name: 148660651

Synonym: MRA_0881

Alternate gene names: NA

Gene position: 975012-973852 (Counterclockwise)

Preceding gene: 148660652

Following gene: 148660649

Centisome position: 22.06

GC content: 70.46

Gene sequence:

>1161_bases
GTGCGGATCGGAGTCGGGGTTTGCACCACGCCCGACGCGCGGCAGGCCGCGGTGGAGGCTGCGGGCCAGGCGCGCGACGA
GCTGGCGGGTGAGGCGCCGTCGCTGGCGGTGTTGCTTGGATCGCGTGCACACACCGACCGGGCTGCCGACGTCCTGAGCG
CGGTGCTGCAGATGATCGATCCGCCCGCGCTTGTCGGTTGCATCGCCCAGGCCATCGTCGCCGGCCGCCACGAGATCGAG
GACGAGCCCGCGGTGGTGGTGTGGCTGGCGTCCGGCTTGGCCGCCGAGACATTCCAGCTGGACTTTGTCCGTACCGGCTC
GGGTGCCCTGATCACCGGTTATCGGTTCGACCGCACCGCCCGGGATCTGCATCTGCTGCTGCCGGACCCGTACACATTCC
CGTCGAACCTGCTCATCGAGCACCCCAACACCGACCTGCCGGGCACCGCCGTCGTGGGCGGCGTGGTGAGCGGCGGGCGC
CGGCGGGGCGACACCCGGCTGTTCCGCGATCACGACGTGCTCACCTCCGGCGTCGTCGGCGTGCGCCTGCCCGGGATGCG
CGGTGTCCCGGTCGTGTCGCAGGGTTGCCGGCCGATCGGCTACCCATACATCGTCACCGGCGCGGACGGCATACTGATCA
CCGAGCTCGGCGGCCGTCCGCCGTTGCAGCGACTGCGTGAGATCGTCGAGGGGCTGTCGCCCGACGAAAGGGCACTCGTC
AGCCACGGCCTACAGATCGGGATCGTCGTCGACGAGCACCTGGCGGCTCCGGGTCAGGGCGATTTCGTGATCCGCGGGCT
GCTCGGCGCCGACCCGTCGACCGGGTCGATCGAGATCGACGAGGTTGTCCAGGTCGGCGCCACCATGCAGTTCCAGGTCC
GTGACGCGGCCGGGGCCGACAAGGACCTACGCCTGACCGTGGAGCGGGCCGCGGCGCGGCTGCCCGGACGCGCGGCTGGA
GCGCTGTTGTTCACCTGCAACGGGCGGGGGCGGCGGATGTTCGGGGTCGCCGACCACGACGCGTCGACGATCGAGGAACT
CCTAGGCGGAATTCCGCTTGCCGGCTTCTTCGCCGCCGGAGAGATCGGCCCGATCGCGGGCCGCAATGCCCTGCACGGAT
TCACCGCATCGATGGCGCTGTTTGTCGACGACATGGAATAG

Upstream 100 bases:

>100_bases
ACGAGGCCGCGGCTCGACGGCCGACCGCGCTTAAGCGCGGTCGGCGCCAACGGTCCGAAGAGCCGCCGACACCCGGGGCA
CATCGGCGCATCATGGAACT

Downstream 100 bases:

>100_bases
AACCTGCACCCAGACGCGATACGCGCCAGCGTGGTACCCGACGAGACTCGGGCGGTCCCCCGCGGACGTGACCGGCCACG
CGGGCGCCCTAAAGTTTCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRIGVGVCTTPDARQAAVEAAGQARDELAGEAPSLAVLLGSRAHTDRAADVLSAVLQMIDPPALVGCIAQAIVAGRHEIE
DEPAVVVWLASGLAAETFQLDFVRTGSGALITGYRFDRTARDLHLLLPDPYTFPSNLLIEHPNTDLPGTAVVGGVVSGGR
RRGDTRLFRDHDVLTSGVVGVRLPGMRGVPVVSQGCRPIGYPYIVTGADGILITELGGRPPLQRLREIVEGLSPDERALV
SHGLQIGIVVDEHLAAPGQGDFVIRGLLGADPSTGSIEIDEVVQVGATMQFQVRDAAGADKDLRLTVERAAARLPGRAAG
ALLFTCNGRGRRMFGVADHDASTIEELLGGIPLAGFFAAGEIGPIAGRNALHGFTASMALFVDDME

Sequences:

>Translated_386_residues
MRIGVGVCTTPDARQAAVEAAGQARDELAGEAPSLAVLLGSRAHTDRAADVLSAVLQMIDPPALVGCIAQAIVAGRHEIE
DEPAVVVWLASGLAAETFQLDFVRTGSGALITGYRFDRTARDLHLLLPDPYTFPSNLLIEHPNTDLPGTAVVGGVVSGGR
RRGDTRLFRDHDVLTSGVVGVRLPGMRGVPVVSQGCRPIGYPYIVTGADGILITELGGRPPLQRLREIVEGLSPDERALV
SHGLQIGIVVDEHLAAPGQGDFVIRGLLGADPSTGSIEIDEVVQVGATMQFQVRDAAGADKDLRLTVERAAARLPGRAAG
ALLFTCNGRGRRMFGVADHDASTIEELLGGIPLAGFFAAGEIGPIAGRNALHGFTASMALFVDDME
>Mature_386_residues
MRIGVGVCTTPDARQAAVEAAGQARDELAGEAPSLAVLLGSRAHTDRAADVLSAVLQMIDPPALVGCIAQAIVAGRHEIE
DEPAVVVWLASGLAAETFQLDFVRTGSGALITGYRFDRTARDLHLLLPDPYTFPSNLLIEHPNTDLPGTAVVGGVVSGGR
RRGDTRLFRDHDVLTSGVVGVRLPGMRGVPVVSQGCRPIGYPYIVTGADGILITELGGRPPLQRLREIVEGLSPDERALV
SHGLQIGIVVDEHLAAPGQGDFVIRGLLGADPSTGSIEIDEVVQVGATMQFQVRDAAGADKDLRLTVERAAARLPGRAAG
ALLFTCNGRGRRMFGVADHDASTIEELLGGIPLAGFFAAGEIGPIAGRNALHGFTASMALFVDDME

Specific function: Unknown

COG id: COG4398

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv0628c

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y874_MYCTU (P0A5D3)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   G70779
- RefSeq:   NP_215389.1
- RefSeq:   NP_335325.1
- EnsemblBacteria:   EBMYCT00000002784
- EnsemblBacteria:   EBMYCT00000072389
- GeneID:   885658
- GeneID:   926207
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0897
- KEGG:   mtu:Rv0874c
- TIGR:   MT0897
- TubercuList:   Rv0874c
- GeneTree:   EBGT00050000018408
- HOGENOM:   HBG292420
- OMA:   IMAKDDE
- ProtClustDB:   CLSK790643
- InterPro:   IPR019494
- InterPro:   IPR013702
- InterPro:   IPR016741
- PIRSF:   PIRSF018953
- SMART:   SM00897

Pfam domain/function: PF08495 FIST; PF10442 FIST_C

EC number: NA

Molecular weight: Translated: 40403; Mature: 40403

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1cbf20d0)-; HASH(0x1c40ce88)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVGVCTTPDARQAAVEAAGQARDELAGEAPSLAVLLGSRAHTDRAADVLSAVLQMID
CEEECEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC
PPALVGCIAQAIVAGRHEIEDEPAVVVWLASGLAAETFQLDFVRTGSGALITGYRFDRTA
CHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCC
RDLHLLLPDPYTFPSNLLIEHPNTDLPGTAVVGGVVSGGRRRGDTRLFRDHDVLTSGVVG
CCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEECCHHHHCCEEE
VRLPGMRGVPVVSQGCRPIGYPYIVTGADGILITELGGRPPLQRLREIVEGLSPDERALV
EECCCCCCCCHHHCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHH
SHGLQIGIVVDEHLAAPGQGDFVIRGLLGADPSTGSIEIDEVVQVGATMQFQVRDAAGAD
HCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEHHHHHHCCCEEEEEEECCCCCC
KDLRLTVERAAARLPGRAAGALLFTCNGRGRRMFGVADHDASTIEELLGGIPLAGFFAAG
CCEEEEHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHCC
EIGPIAGRNALHGFTASMALFVDDME
CCCCCCCCCHHHHHHEEEEEEEECCH
>Mature Secondary Structure
MRIGVGVCTTPDARQAAVEAAGQARDELAGEAPSLAVLLGSRAHTDRAADVLSAVLQMID
CEEECEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC
PPALVGCIAQAIVAGRHEIEDEPAVVVWLASGLAAETFQLDFVRTGSGALITGYRFDRTA
CHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCC
RDLHLLLPDPYTFPSNLLIEHPNTDLPGTAVVGGVVSGGRRRGDTRLFRDHDVLTSGVVG
CCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEECCHHHHCCEEE
VRLPGMRGVPVVSQGCRPIGYPYIVTGADGILITELGGRPPLQRLREIVEGLSPDERALV
EECCCCCCCCHHHCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHH
SHGLQIGIVVDEHLAAPGQGDFVIRGLLGADPSTGSIEIDEVVQVGATMQFQVRDAAGAD
HCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEHHHHHHCCCEEEEEEECCCCCC
KDLRLTVERAAARLPGRAAGALLFTCNGRGRRMFGVADHDASTIEELLGGIPLAGFFAAG
CCEEEEHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHCC
EIGPIAGRNALHGFTASMALFVDDME
CCCCCCCCCHHHHHHEEEEEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036