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The map label for this gene is moaC

Identifier: 148660641

GI number: 148660641

Start: 964196

End: 964699

Strand: Direct

Name: moaC

Synonym: MRA_0871

Alternate gene names: 148660641

Gene position: 964196-964699 (Clockwise)

Preceding gene: 148660640

Following gene: 148660642

Centisome position: 21.81

GC content: 65.08

Gene sequence:

>504_bases
ATGGCCAGGGCTTCTGGGGCATCCGACTACCGCTCGGGCGAGCTGTCGCACCAGGATGAGCGGGGGGCAGCGCACATGGT
CGATATCACCGAGAAGGCAACCACGAAGCGAACAGCCGTTGCCGCGGGCATCTTACGTACCTCGGCGCAGGTGGTGGCGC
TGATCTCGACTGGCGGGCTGCCCAAAGGGGATGCGCTGGCCACCGCGCGGGTGGCGGGCATTATGGCGGCCAAGCGCACC
AGCGACCTGATCCCGCTGTGCCATCAACTCGCGCTTACCGGAGTCGACGTCGATTTCACCGTCGGCCAGTTGGATATCGA
GATCACAGCGACGGTACGCAGTACCGACCGAACGGGCGTCGAGATGGAAGCGCTGACCGCTGTCAGCGTGGCCGCCCTCA
CGCTCTACGACATGATCAAGGCGGTCGATCCGGGCGCGCTTATCGATGACATCCGGGTGCTCCACAAAGAAGGCGGTCGT
CGCGGGACCTGGACGAGGCGATGA

Upstream 100 bases:

>100_bases
GGGTGCGCTATCACCCTTCGGTGAATTGACGTTCCCGGTACCGTCCGACGACCTGCCCTACATCCACCCGGTGACCGTCA
TCAATCGGTAAGCCGCCAGG

Downstream 100 bases:

>100_bases
GCACCCGGTCCGCTCGAATTGTCGTTGTGTCGAGCCGCGCGGCGGCCGGTGTGTATACCGATGATTGCGGGCCGATTATC
GCTGGATGGCTTGAACAGCA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRT
SDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGR
RGTWTRR

Sequences:

>Translated_167_residues
MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRT
SDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGR
RGTWTRR
>Mature_166_residues
ARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTS
DLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRR
GTWTRR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=49.0196078431373, Blast_Score=133, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI32566331, Length=148, Percent_Identity=41.8918918918919, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=47.1337579617834, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574492, Length=138, Percent_Identity=48.5507246376812, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC2_MYCBO (P0A5K7)

Other databases:

- EMBL:   BX248336
- RefSeq:   NP_854545.1
- ProteinModelPortal:   P0A5K7
- SMR:   P0A5K7
- EnsemblBacteria:   EBMYCT00000014756
- GeneID:   1092764
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0888
- GeneTree:   EBGT00050000016668
- HOGENOM:   HBG605231
- ProtClustDB:   PRK09364
- BioCyc:   MBOV233413:MB0888-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17598; Mature: 17467

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: ACT_SITE 137-137

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
PKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGV
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEECCCCCCC
EMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGL
CCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
PKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGV
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEECCCCCCC
EMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972