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The map label for this gene is ercc3 [C]

Identifier: 148660638

GI number: 148660638

Start: 959829

End: 961457

Strand: Reverse

Name: ercc3 [C]

Synonym: MRA_0869

Alternate gene names: 148660638

Gene position: 961457-959829 (Counterclockwise)

Preceding gene: 148660639

Following gene: 148660635

Centisome position: 21.75

GC content: 64.46

Gene sequence:

>1629_bases
GTGCAGTCCGATAAGACGGTGCTGTTGGAAGTCGACCATGAACTGGCCGGCGCTGCACGCGCCGCCATCGCGCCGTTCGC
CGAGCTGGAACGTGCACCCGAACATGTCCACACCTACCGCATCACACCGCTGGCACTGTGGAATGCTCGCGCCGCCGGCC
ATGATGCCGAGCAAGTCGTCGACGCGCTGGTCAGTTACTCCCGCTACGCGGTGCCGCAACCCTTGCTCGTCGACATCGTC
GACACCATGGCCCGCTACGGACGACTGCAGTTGGTCAAGAACCCGGCCCATGGCCTGACGCTGGTGAGCCTGGACCGCGC
GGTGCTTGAGGAAGTGCTGCGCAACAAGAAGATCGCGCCGATGCTTGGCGCCCGCATCGATGACGACACCGTCGTCGTCC
ACCCCAGCGAACGCGGCCGGGTCAAGCAGCTGCTGCTCAAGATCGGTTGGCCCGCAGAGGATCTCGCCGGCTACGTCGAT
GGTGAAGCGCACCCGATCAGCCTGCACCAGGAGGGCTGGCAGCTGCGCGATTACCAGCGGCTGGCCGCGGACTCGTTCTG
GGCGGGCGGCTCCGGGGTGGTGGTGCTGCCATGTGGGGCCGGCAAGACGCTGGTCGGTGCGGCCGCAATGGCCAAAGCCG
GCGCGACGACGTTGATCCTGGTCACCAATATCGTCGCGGCCCGGCAATGGAAACGAGAGCTGGTCGCGCGCACCTCGCTC
ACCGAGAATGAGATCGGCGAATTCTCGGGAGAACGCAAGGAAATCCGACCTGTCACCATCTCGACATACCAGATGATCAC
CCGCCGCACTAAGGGCGAGTACCGCCATCTGGAACTGTTCGACAGCCGCGACTGGGGGCTCATCATCTATGACGAGGTGC
ACCTGTTGCCGGCACCGGTCTTCCGGATGACCGCTGACCTGCAGTCCAAACGGCGGCTGGGGCTGACCGCCACGTTGATC
CGTGAAGACGGACGCGAGGGCGACGTGTTTTCCCTTATCGGACCAAAGCGCTATGACGCGCCGTGGAAGGACATTGAGGC
GCAGGGCTGGATCGCGCCAGCTGAGTGCGTGGAAGTCCGGGTCACGATGACCGACAGCGAGCGGATGATGTACGCCACCG
CCGAACCCGAAGAACGCTACCGGATCTGCTCGACGGTGCACACCAAAATTGCTGTGGTCAAGTCGATTCTGGCGAAGCAC
CCGGATGAGCAGACCCTGGTCATCGGAGCGTACTTGGATCAGCTCGACGAGCTGGGCGCCGAGCTCGGCGCTCCGGTGAT
TCAGGGGTCGACAAGGACCAGCGAACGCGAGGCACTGTTCGACGCCTTCCGCCGCGGCGAGGTCGCTACGCTCGTGGTGT
CCAAGGTGGCTAACTTCTCCATCGACTTGCCGGAAGCCGCCGTGGCGGTACAGGTTTCGGGAACATTCGGCTCACGCCAG
GAAGAGGCGCAACGGCTCGGCCGGATATTGCGACCCAAGGCCGACGGGGGCGGTGCCATCTTCTACTCGGTGGTGGCCCG
CGACAGCCTGGATGCCGAGTACGCCGCACACCGGCAGCGGTTTTTAGCTGAGCAGGGCTACGGTTACATCATCCGCGACG
CCGACGACCTGCTGGGCCCGGCAATTTAG

Upstream 100 bases:

>100_bases
CGCAGCGATGAGGAGGAGCGGCGCCATTGACTACCGCCGGCGACGATGCAGAGCGCAGCGATGAGGAGGAGCGGCGCCAT
TGACTGACGGACCATTGATA

Downstream 100 bases:

>100_bases
GTTGCGCGAGCAGACGTAAAAGCCCCCGACACGCCGAGCGTGCGGGGGCTTTTACGTCTGCTCGCGCTCAGCTTAGCAGC
GACTCCGGCGGCAGGAAGCG

Product: putative ATP-dependent DNA helicase

Products: NA

Alternate protein names: DNA Repair Helicase; Type III Restriction Res Subunit; Helicase Domain Protein; Helicase Domain-Containing Protein; ATP-Dependent DNA Helicase; DNA Repair Helicase RAD; DNA Repair Helicase Rad; Type III Restriction Res Subunit Family; Superfamily II DNA/RNA Helicase; DNA/RNA Helicase; DNA Repair Protein Rad; Helicase; DNA Repair Protein RAD; DNA Helicase; DNA Repair Protein; DNA/RNA Helicase Superfamily II; Helicase-Like Protein; Helicase Protein; ATP-Dependent Helicase; DNA Or RNA Helicase Of Superfamily II; Helicase ATP-Dependent; Helicase DNA Repair; DNA Or RNA Helicase; Helicase DNA Repair Rad; RAD25-Type DNA Repair Helicase; DNA Repair Related Protein; Restriction Endonuclease Family Protein; XPB/RAD25-Related Helicase; Helicase ATP-Dependent Intein-Containing; DEAD/DEAH Box Helicase-Like; DNA-Helicase; DNA/RNA Repair Helicase; DNA Or RNA Helicase Of Superfamily Protein II; DEAD/DEAH Box Helicase

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MQSDKTVLLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDALVSYSRYAVPQPLLVDIV
DTMARYGRLQLVKNPAHGLTLVSLDRAVLEEVLRNKKIAPMLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAGYVD
GEAHPISLHQEGWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGATTLILVTNIVAARQWKRELVARTSL
TENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLGLTATLI
REDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECVEVRVTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKH
PDEQTLVIGAYLDQLDELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTFGSRQ
EEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI

Sequences:

>Translated_542_residues
MQSDKTVLLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDALVSYSRYAVPQPLLVDIV
DTMARYGRLQLVKNPAHGLTLVSLDRAVLEEVLRNKKIAPMLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAGYVD
GEAHPISLHQEGWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGATTLILVTNIVAARQWKRELVARTSL
TENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLGLTATLI
REDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECVEVRVTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKH
PDEQTLVIGAYLDQLDELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTFGSRQ
EEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI
>Mature_542_residues
MQSDKTVLLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDALVSYSRYAVPQPLLVDIV
DTMARYGRLQLVKNPAHGLTLVSLDRAVLEEVLRNKKIAPMLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAGYVD
GEAHPISLHQEGWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGATTLILVTNIVAARQWKRELVARTSL
TENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLGLTATLI
REDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECVEVRVTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKH
PDEQTLVIGAYLDQLDELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTFGSRQ
EEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557563, Length=375, Percent_Identity=36.2666666666667, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17556358, Length=379, Percent_Identity=35.8839050131926, Blast_Score=234, Evalue=6e-62,
Organism=Saccharomyces cerevisiae, GI6322048, Length=602, Percent_Identity=29.734219269103, Blast_Score=261, Evalue=3e-70,
Organism=Drosophila melanogaster, GI221331068, Length=375, Percent_Identity=36, Blast_Score=235, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24662247, Length=375, Percent_Identity=36, Blast_Score=235, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 59805; Mature: 59805

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSDKTVLLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVV
CCCCCEEEEEECCHHHHHHHHHHCCHHHHHCCHHHHHEEEECEEEEECCCCCCCCHHHHH
DALVSYSRYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRAVLEEVLRNKKIAP
HHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCH
MLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAGYVDGEAHPISLHQEGWQLRDYQR
HHCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHH
LAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGATTLILVTNIVAARQWKRELVARTSL
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCC
TENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPV
CHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCCH
FRMTADLQSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECVEVR
HHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEE
VTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLVIGAYLDQLDELGA
EEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
ELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTFGSRQ
HHCCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCH
EEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGP
HHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHCCC
AI
CC
>Mature Secondary Structure
MQSDKTVLLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVV
CCCCCEEEEEECCHHHHHHHHHHCCHHHHHCCHHHHHEEEECEEEEECCCCCCCCHHHHH
DALVSYSRYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRAVLEEVLRNKKIAP
HHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCH
MLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAGYVDGEAHPISLHQEGWQLRDYQR
HHCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHH
LAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGATTLILVTNIVAARQWKRELVARTSL
HHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCC
TENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPV
CHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCCH
FRMTADLQSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECVEVR
HHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEE
VTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLVIGAYLDQLDELGA
EEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
ELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTFGSRQ
HHCCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCH
EEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGP
HHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHCCC
AI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA