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The map label for this gene is yceL [C]

Identifier: 148660626

GI number: 148660626

Start: 947362

End: 948621

Strand: Direct

Name: yceL [C]

Synonym: MRA_0857

Alternate gene names: 148660626

Gene position: 947362-948621 (Clockwise)

Preceding gene: 148660625

Following gene: 148660627

Centisome position: 21.43

GC content: 63.81

Gene sequence:

>1260_bases
ATGGGAGCGCGCGCTATATTCCGCGGGTTCAACCGCCCGAGCCGGGTGTTGATGATCAACCAGTTCGGCATCAACATCGG
CTTCTACATGCTGATGCCGTACCTGGCCGACTACCTAGCCGGGCCACTGGGGCTAGCCGCGTGGGCGGTGGGTCTGGTGA
TGGGCGTGCGCAATTTCTCCCAGCAGGGCATGTTCTTCGTGGGTGGCACGCTGGCCGATCGGTTCGGCTACAAGCCACTG
ATCATCGCCGGATGTCTGATCCGCACCGGCGGGTTTGCCTTGCTGGTGGTCGCCCAGTCGCTGCCCAGTGTGCTGATCGC
CGCGGCTGCCACGGGCTTTGCCGGCGCGCTGTTCAATCCCGCGGTGCGCGGCTATCTCGCGGCCGAAGCCGGGGAACGCA
AGATCGAAGCGTTCGCGATGTTCAACGTCTTCTACCAGTCGGGGATCCTGCTCGGCCCGCTGGTTGGATTAGTATTGCTG
GCGCTGGATTTCCGGATCACGGTGCTGGCCGCCGCCGGTGTGTTCGGCCTACTCACCGTCGCGCAGCTGGTCGCACTGCC
CCAACACCGGGCCGACTCGGAGCGCGAAAAAACATCGATCCTGCAGGACTGGCGGGTCGTCGTTCGCAACCGTCCGTTTC
TGACGTTAGCCGCCGCCATGACCGGATGCTATGCGCTGTCGTTCCAGATCTATCTGGCTCTGCCCATGCAGGCGTCGATC
CTCATGCCACGCAACCAATATCTCTTGATTGCGGCGATGTTCGCGGTATCGGGTCTGGTCGCCGTCGGCGGGCAGCTGCG
CATCACCCGCTGGTTCGCCGTCAGATGGGGGGCCGAGCGCAGCCTGGTAGTCGGCGCGACGATTTTGGCGGCCTCGTTCA
TCCCGGTTGCAGTCATCCCAAACGGCCAGCGGTTCGGCGTCGCCGTTGCGGTCATGGCATTGGTGCTGTCGGCGAGTCTG
CTGGCGGTTGCCTCGGCAGCGTTGTTTCCTTTCGAAATGCGTGCCGTGGTCGCACTGTCGGGCGACCGGCTGGTGGCGAC
CCACTACGGGTTCTACAGCACCATCGTGGGCGTCGGAGTCCTCGTCGGAAATCTGGCGATCGGATCGCTCATGAGCGCCG
CGCGCCGCTTAAATACCGATGAAATTGTTTGGGGCGGATTGATTCTGGTGGGCATCGTTGCGGTGGCCGGGCTCCGTCGG
TTGGACACATTCACCTCGGGTTCCCAGAACATGACCGGTCGGTGGGCTGCACCCCGGTGA

Upstream 100 bases:

>100_bases
CTCCCACCGAGCCCGACGAGATTGCCTCGCCGCTAGACGCCGTCGTCACCCGATGGACACGCAGCACCACGGTGATCGAT
CCAACCCAGGTGGTGTCGTA

Downstream 100 bases:

>100_bases
CCCGCGATCCACACAGCCCGGACTGCGGGCGCGAGGGCAGCTACCGCGACACCATCACCCGCCCGTTGACCGACCTACCG
GTGGCCGGCTATCCGTTGGT

Product: putative integral membrane transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPL
IIAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNPAVRGYLAAEAGERKIEAFAMFNVFYQSGILLGPLVGLVLL
ALDFRITVLAAAGVFGLLTVAQLVALPQHRADSEREKTSILQDWRVVVRNRPFLTLAAAMTGCYALSFQIYLALPMQASI
LMPRNQYLLIAAMFAVSGLVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIPVAVIPNGQRFGVAVAVMALVLSASL
LAVASAALFPFEMRAVVALSGDRLVATHYGFYSTIVGVGVLVGNLAIGSLMSAARRLNTDEIVWGGLILVGIVAVAGLRR
LDTFTSGSQNMTGRWAAPR

Sequences:

>Translated_419_residues
MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPL
IIAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNPAVRGYLAAEAGERKIEAFAMFNVFYQSGILLGPLVGLVLL
ALDFRITVLAAAGVFGLLTVAQLVALPQHRADSEREKTSILQDWRVVVRNRPFLTLAAAMTGCYALSFQIYLALPMQASI
LMPRNQYLLIAAMFAVSGLVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIPVAVIPNGQRFGVAVAVMALVLSASL
LAVASAALFPFEMRAVVALSGDRLVATHYGFYSTIVGVGVLVGNLAIGSLMSAARRLNTDEIVWGGLILVGIVAVAGLRR
LDTFTSGSQNMTGRWAAPR
>Mature_418_residues
GARAIFRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLI
IAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNPAVRGYLAAEAGERKIEAFAMFNVFYQSGILLGPLVGLVLLA
LDFRITVLAAAGVFGLLTVAQLVALPQHRADSEREKTSILQDWRVVVRNRPFLTLAAAMTGCYALSFQIYLALPMQASIL
MPRNQYLLIAAMFAVSGLVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIPVAVIPNGQRFGVAVAVMALVLSASLL
AVASAALFPFEMRAVVALSGDRLVATHYGFYSTIVGVGVLVGNLAIGSLMSAARRLNTDEIVWGGLILVGIVAVAGLRRL
DTFTSGSQNMTGRWAAPR

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI87081828, Length=290, Percent_Identity=27.9310344827586, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y849_MYCTU (O53861)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   A70814
- RefSeq:   NP_215364.1
- ProteinModelPortal:   O53861
- EnsemblBacteria:   EBMYCT00000000398
- EnsemblBacteria:   EBMYCT00000095927
- GeneID:   885111
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv0849
- TIGR:   MT0872
- TubercuList:   Rv0849
- GeneTree:   EBGT00050000014793
- HOGENOM:   HBG428901
- OMA:   RAYVAAD
- ProtClustDB:   CLSK871862
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 44514; Mature: 44383

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c587398)-; HASH(0x1c9ab7cc)-; HASH(0x1d14ca5c)-; HASH(0x1cb400d4)-; HASH(0x1ba5df44)-; HASH(0x1c784408)-; HASH(0x1bc476c8)-; HASH(0x1b9bcc74)-; HASH(0x1c1ab810)-; HASH(0x1cb58558)-; HASH(0x1c7c3d7c)-; HASH(0x1d2aa4cc)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFS
CCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
QQGMFFVGGTLADRFGYKPLIIAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNP
CCCEEEECCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRGYLAAEAGERKIEAFAMFNVFYQSGILLGPLVGLVLLALDFRITVLAAAGVFGLLTV
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLVALPQHRADSEREKTSILQDWRVVVRNRPFLTLAAAMTGCYALSFQIYLALPMQASI
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEEEECCCEEE
LMPRNQYLLIAAMFAVSGLVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIPVAVIP
ECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEC
NGQRFGVAVAVMALVLSASLLAVASAALFPFEMRAVVALSGDRLVATHYGFYSTIVGVGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCEEEEEHHHHHHHHHHHHH
LVGNLAIGSLMSAARRLNTDEIVWGGLILVGIVAVAGLRRLDTFTSGSQNMTGRWAAPR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
>Mature Secondary Structure 
GARAIFRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFS
CCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
QQGMFFVGGTLADRFGYKPLIIAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNP
CCCEEEECCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRGYLAAEAGERKIEAFAMFNVFYQSGILLGPLVGLVLLALDFRITVLAAAGVFGLLTV
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLVALPQHRADSEREKTSILQDWRVVVRNRPFLTLAAAMTGCYALSFQIYLALPMQASI
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEEEEEEECCCEEE
LMPRNQYLLIAAMFAVSGLVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIPVAVIP
ECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEC
NGQRFGVAVAVMALVLSASLLAVASAALFPFEMRAVVALSGDRLVATHYGFYSTIVGVGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCEEEEEHHHHHHHHHHHHH
LVGNLAIGSLMSAARRLNTDEIVWGGLILVGIVAVAGLRRLDTFTSGSQNMTGRWAAPR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036