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The map label for this gene is pepC [H]

Identifier: 148660578

GI number: 148660578

Start: 894624

End: 895925

Strand: Direct

Name: pepC [H]

Synonym: MRA_0810

Alternate gene names: 148660578

Gene position: 894624-895925 (Clockwise)

Preceding gene: 148660575

Following gene: 148660579

Centisome position: 20.24

GC content: 69.05

Gene sequence:

>1302_bases
ATGGCGGCCACGGCACACGGCCTGTGCGAATTCATCGACGCGTCCCCGTCGCCGTTTCACGTCTGCGCGACGGTGGCGGG
ACGGCTGCTCGGCGCCGGATACCGCGAGCTGCGCGAAGCGGATCGCTGGCCGGACAAACCGGGCCGGTACTTCACCGTCC
GGGCTGGCTCGCTGGTGGCGTGGAACGCCGAGCAGAGCGGGCACACGCAGGTCCCATTCCGGATCGTCGGCGCGCACACC
GACAGCCCCAATCTGCGGGTCAAGCAGCATCCGGACAGGCTCGTCGCCGGCTGGCACGTGGTGGCGCTGCAACCGTATGG
GGGAGTTTGGCTGCACTCCTGGCTGGATCGCGATCTGGGCATCAGCGGGCGGCTATCGGTGCGTGACGGTACCGGGGTCA
GCCACCGGCTGGTCCTGATCGACGACCCGATCCTGCGGGTGCCGCAGCTGGCGATTCACCTGGCCGAGGACCGCAAGTCG
CTCACGCTCGATCCGCAACGACACATCAACGCTGTATGGGGCGTGGGAGAGCGGGTGGAGTCCTTTGTGGGGTACGTCGC
TCAGCGCGCCGGGGTGGCGGCGGCCGACGTGCTGGCCGCGGACCTGATGACCCATGACTTGACCCCGTCGGCGCTGATCG
GCGCTTCGGTCAACGGCACTGCCAGCCTGCTCAGCGCGCCGCGGCTGGACAACCAGGCCAGTTGCTATGCCGGGATGGAG
GCACTGCTGGCCGTGGACGTGGACTCGGCGTCGAGCGGATTCGTGCCCGTGCTGGCGATTTTCGACCACGAGGAGGTGGG
ATCGGCCTCGGGCCACGGCGCACAGTCCGATCTGCTATCCAGCGTGCTCGAACGCATCGTGCTCGCGGCGGGCGGCACCC
GGGAGGACTTCCTGCGCCGACTGACCACCTCGATGCTCGCCTCGGCCGACATGGCGCATGCGACGCACCCCAACTACCCG
GACCGTCACGAGCCGAGCCACCCGATCGAAGTCAACGCGGGTCCGGTGCTCAAGGTGCACCCAAATCTGCGCTACGCCAC
CGACGGACGCACCGCGGCGGCGTTCGCACTGGCCTGCCAGCGCGCGGGAGTGCCTATGCAGCGTTACGAACATCGCGCCG
ATCTGCCGTGCGGGTCGACGATCGGGCCGTTGGCCGCGGCGCGCACCGGAATCCCCACGGTCGACGTCGGCGCCGCCCAG
CTGGCGATGCACTCCGCGCGAGAGTTGATGGGCGCTCACGACGTAGCCGCCTATTCGGCGGCACTGCAAGCGTTTCTTTC
CGCCGAGCTATCCGAGGCATAG

Upstream 100 bases:

>100_bases
GCGGCCGGAGTCAACGGCGCCAGAATCGGCTGCGGAGAGACAGCAGGCACAGCCACGACCCTAACGTCCCTGCAATACCG
GTGATGCTAGACATGGCTAC

Downstream 100 bases:

>100_bases
GGTCGGGCGGTATGGCACTCAAGGTAGAGATGGTCACTTTCGACTGCAGCGACCCTGCGAAGCTTGCCGGCTGGTGGGCC
GAGCAGTTCGATGGCACGAC

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MAATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHT
DSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRDGTGVSHRLVLIDDPILRVPQLAIHLAEDRKS
LTLDPQRHINAVWGVGERVESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGME
ALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYP
DRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQ
LAMHSARELMGAHDVAAYSAALQAFLSAELSEA

Sequences:

>Translated_433_residues
MAATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHT
DSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRDGTGVSHRLVLIDDPILRVPQLAIHLAEDRKS
LTLDPQRHINAVWGVGERVESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGME
ALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYP
DRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQ
LAMHSARELMGAHDVAAYSAALQAFLSAELSEA
>Mature_432_residues
AATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHTD
SPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRDGTGVSHRLVLIDDPILRVPQLAIHLAEDRKSL
TLDPQRHINAVWGVGERVESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGMEA
LLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYPD
RHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQL
AMHSARELMGAHDVAAYSAALQAFLSAELSEA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=456, Percent_Identity=35.7456140350877, Blast_Score=258, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17552916, Length=437, Percent_Identity=36.8421052631579, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321905, Length=461, Percent_Identity=32.9718004338395, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6322746, Length=454, Percent_Identity=29.9559471365639, Blast_Score=189, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 46013; Mature: 45882

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVA
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCEEE
WNAEQSGHTQVPFRIVGAHTDSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLG
ECCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEEECEEEEEECCCCCHHHHHHHHHCCC
ISGRLSVRDGTGVSHRLVLIDDPILRVPQLAIHLAEDRKSLTLDPQRHINAVWGVGERVE
CCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHH
SFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGME
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHH
ALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRR
EEEEEECCCCCCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LTTSMLASADMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEECCCCEEECCCCHHHHHHHHHH
RAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSA
HCCCCHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALQAFLSAELSEA
HHHHHHHHHHCCC
>Mature Secondary Structure 
AATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVA
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCEEE
WNAEQSGHTQVPFRIVGAHTDSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLG
ECCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEEECEEEEEECCCCCHHHHHHHHHCCC
ISGRLSVRDGTGVSHRLVLIDDPILRVPQLAIHLAEDRKSLTLDPQRHINAVWGVGERVE
CCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHH
SFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGME
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHH
ALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRR
EEEEEECCCCCCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LTTSMLASADMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEECCCCEEECCCCHHHHHHHHHH
RAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSA
HCCCCHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALQAFLSAELSEA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]