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The map label for this gene is 148660562

Identifier: 148660562

GI number: 148660562

Start: 880646

End: 882346

Strand: Direct

Name: 148660562

Synonym: MRA_0794

Alternate gene names: NA

Gene position: 880646-882346 (Clockwise)

Preceding gene: 148660561

Following gene: 148660564

Centisome position: 19.92

GC content: 64.2

Gene sequence:

>1701_bases
GTGGCGTTAACCTGTACCGACATGAGCGATGCTGTAGCCGGTTCAGATGCCGAGGGGCTCACCGCTGATGCCATTGTCGT
GGGAGCCGGATTAGCGGGCCTGGTAGCCGCTTGTGAGTTGGCCGACCGCGGCCTACGGGTGCTGATCCTCGACCAGGAGA
ATCGGGCCAACGTGGGCGGGCAGGCCTTCTGGTCGTTCGGCGGTTTGTTCTTGGTCAACAGTCCCGAGCAGCGCCGCTTG
GGCATCCGTGATAGCCATGAGCTTGCTCTGCAGGATTGGCTGGGGACGGCGGCGTTCGACCGGCCCGAGGACTACTGGCC
CGAACAATGGGCGCATGCTTACGTCGATTTCGCGGCGGGGGAGAAGCGCAGCTGGCTGCGGGCCCGCGGGCTGAAGATCT
TTCCGCTGGTGGGCTGGGCCGAGCGTGGTGGTTACGACGCGCAGGGGCACGGCAACTCGGTGCCCCGTTTCCACATCACC
TGGGGTACTGGGCCGGCTCTGGTCGACATATTCGTGCGTCAGCTGCGTGATCGCCCCACGGTGCGCTTTGCGCACCGCCA
CCAGGTCGACAAACTGATCGTCGAGGGTAACGCGGTGACAGGCGTTCGGGGTACCGTGCTGGAGCCCTCGGATGAGCCGC
GCGGCGCGCCTTCGTCGCGAAAGTCTGTGGGGAAATTCGAGTTTCGCGCGTCAGCGGTGATCGTCGCCAGTGGTGGTATC
GGTGGCAATCATGAGCTGGTGCGCAAAAACTGGCCGAGACGGATGGGCCGCATTCCCAAGCAACTGTTGAGCGGGGTGCC
CGCGCACGTTGATGGCAGGATGATCGGCATCGCTCAAAAGGCCGGGGCTGCGGTGATCAATCCGGACCGGATGTGGCATT
ACACCGAAGGCATTACCAACTACGACCCGATCTGGCCGCGGCACGGTATCCGGATTATTCCGGGGCCGTCGTCGCTATGG
CTGGATGCCGCGGGCAAGCGGTTGCCGGTACCGTTGTTTCCCGGGTTCGACACCCTCGGCACATTGGAGTACATCACCAA
GTCTGGACATGACTACACCTGGTTCGTGTTGAATGCCAAGATAATCGAGAAGGAATTCGCGCTGTCCGGTCAGGAGCAGA
ACCCTGACTTGACCGGTCGGCGCCTGGGCCAGCTGTTGCGCTCTCGGGCTCACGCCGGCCCGCCCGGACCGGTGCAGGCA
TTCATCGATCGTGGTGTGGACTGCGTCCACGCGAACTCGTTGCGCGAGTTGGTGGCCGCGATGAACGAGTTGCCCGATGT
GGTGCCGCTGGACTACGAGACGGTGGCAGCCGCGGTCACTGCGCGCGATCGTGAGGTGGTCAATAAGTACAGCAAGGATG
GACAGATCACCGCGATTCGTGCCGCTCGCCGCTACCGAGGCGACCGATTTGGCCGGGTGGTGGCGCCACATCGGTTGACC
GATCCGAAGGCCGGGCCGCTGATCGCGGTCAAGCTGCACATCCTGACTCGAAAGACGTTGGGTGGCATCGAAACTGACTT
AGATGCTCGGGTGCTCAAGGCCGACGGTACGCCACTGGCCGGGTTGTATGCAGCCGGCGAGGTCGCCGGGTTCGGCGGGG
GCGGTGTCCATGGCTACCGGGCCTTGGAGGGCACCTTCCTGGGTGGATGCATATTTTCCGGCCGCGCTGCCGGCCGCGGG
GCCGCCGAGGATATCCGCTAG

Upstream 100 bases:

>100_bases
TGCCGTCGACCTGGCGATGCTGCAGGGGTGCACACCGATGGTGTACCGGTGGCGAGCCGATGCGGCGGTACTCGACGCGG
CCTGACCGAGCGCCTGATCG

Downstream 100 bases:

>100_bases
TTGTGGCCGCTTGACATAGGAGCTATTGCTCGCGCTAGAAGGTGACCGCGCTTTCCTCGGGCAACACCTGAAAGTCGGTG
GTGGTCATCTCGGTGAGCCG

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLILDQENRANVGGQAFWSFGGLFLVNSPEQRRL
GIRDSHELALQDWLGTAAFDRPEDYWPEQWAHAYVDFAAGEKRSWLRARGLKIFPLVGWAERGGYDAQGHGNSVPRFHIT
WGTGPALVDIFVRQLRDRPTVRFAHRHQVDKLIVEGNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVASGGI
GGNHELVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVINPDRMWHYTEGITNYDPIWPRHGIRIIPGPSSLW
LDAAGKRLPVPLFPGFDTLGTLEYITKSGHDYTWFVLNAKIIEKEFALSGQEQNPDLTGRRLGQLLRSRAHAGPPGPVQA
FIDRGVDCVHANSLRELVAAMNELPDVVPLDYETVAAAVTARDREVVNKYSKDGQITAIRAARRYRGDRFGRVVAPHRLT
DPKAGPLIAVKLHILTRKTLGGIETDLDARVLKADGTPLAGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRG
AAEDIR

Sequences:

>Translated_566_residues
MALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLILDQENRANVGGQAFWSFGGLFLVNSPEQRRL
GIRDSHELALQDWLGTAAFDRPEDYWPEQWAHAYVDFAAGEKRSWLRARGLKIFPLVGWAERGGYDAQGHGNSVPRFHIT
WGTGPALVDIFVRQLRDRPTVRFAHRHQVDKLIVEGNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVASGGI
GGNHELVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVINPDRMWHYTEGITNYDPIWPRHGIRIIPGPSSLW
LDAAGKRLPVPLFPGFDTLGTLEYITKSGHDYTWFVLNAKIIEKEFALSGQEQNPDLTGRRLGQLLRSRAHAGPPGPVQA
FIDRGVDCVHANSLRELVAAMNELPDVVPLDYETVAAAVTARDREVVNKYSKDGQITAIRAARRYRGDRFGRVVAPHRLT
DPKAGPLIAVKLHILTRKTLGGIETDLDARVLKADGTPLAGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRG
AAEDIR
>Mature_565_residues
ALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLILDQENRANVGGQAFWSFGGLFLVNSPEQRRLG
IRDSHELALQDWLGTAAFDRPEDYWPEQWAHAYVDFAAGEKRSWLRARGLKIFPLVGWAERGGYDAQGHGNSVPRFHITW
GTGPALVDIFVRQLRDRPTVRFAHRHQVDKLIVEGNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVASGGIG
GNHELVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVINPDRMWHYTEGITNYDPIWPRHGIRIIPGPSSLWL
DAAGKRLPVPLFPGFDTLGTLEYITKSGHDYTWFVLNAKIIEKEFALSGQEQNPDLTGRRLGQLLRSRAHAGPPGPVQAF
IDRGVDCVHANSLRELVAAMNELPDVVPLDYETVAAAVTARDREVVNKYSKDGQITAIRAARRYRGDRFGRVVAPHRLTD
PKAGPLIAVKLHILTRKTLGGIETDLDARVLKADGTPLAGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGA
AEDIR

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y0785_MYCTU (P71838)

Other databases:

- EMBL:   BX842574
- PIR:   D70709
- RefSeq:   NP_215299.1
- HSSP:   P83223
- ProteinModelPortal:   P71838
- EnsemblBacteria:   EBMYCT00000000667
- GeneID:   885864
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv0785
- TubercuList:   Rv0785
- GeneTree:   EBGT00050000015551
- HOGENOM:   HBG571282
- OMA:   GCLFSGR
- ProtClustDB:   PRK12834
- PIRSF:   PIRSF036654

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 61252; Mature: 61121

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLILDQENRANVGG
CEEEECCCHHHHCCCCCCCCEECCEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
QAFWSFGGLFLVNSPEQRRLGIRDSHELALQDWLGTAAFDRPEDYWPEQWAHAYVDFAAG
HHHHCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
EKRSWLRARGLKIFPLVGWAERGGYDAQGHGNSVPRFHITWGTGPALVDIFVRQLRDRPT
CCHHHHHHCCCEEEEEECCHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCC
VRFAHRHQVDKLIVEGNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVASGGI
EEEHHHHCCCEEEEECCEEECCCCEEECCCCCCCCCCCCHHCCCCEEEEEEEEEEEECCC
GGNHELVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVINPDRMWHYTEGITN
CCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEEHHCCCEEECCCCCEEECCCCCC
YDPIWPRHGIRIIPGPSSLWLDAAGKRLPVPLFPGFDTLGTLEYITKSGHDYTWFVLNAK
CCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEEE
IIEKEFALSGQEQNPDLTGRRLGQLLRSRAHAGPPGPVQAFIDRGVDCVHANSLRELVAA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHH
MNELPDVVPLDYETVAAAVTARDREVVNKYSKDGQITAIRAARRYRGDRFGRVVAPHRLT
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCEECCCCCC
DPKAGPLIAVKLHILTRKTLGGIETDLDARVLKADGTPLAGLYAAGEVAGFGGGGVHGYR
CCCCCCEEEEEEEEEHHHHHCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCEE
ALEGTFLGGCIFSGRAAGRGAAEDIR
EECCCEEEEEEECCCCCCCCCHHCCC
>Mature Secondary Structure 
ALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLILDQENRANVGG
EEEECCCHHHHCCCCCCCCEECCEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
QAFWSFGGLFLVNSPEQRRLGIRDSHELALQDWLGTAAFDRPEDYWPEQWAHAYVDFAAG
HHHHCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
EKRSWLRARGLKIFPLVGWAERGGYDAQGHGNSVPRFHITWGTGPALVDIFVRQLRDRPT
CCHHHHHHCCCEEEEEECCHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCC
VRFAHRHQVDKLIVEGNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVASGGI
EEEHHHHCCCEEEEECCEEECCCCEEECCCCCCCCCCCCHHCCCCEEEEEEEEEEEECCC
GGNHELVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVINPDRMWHYTEGITN
CCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEEHHCCCEEECCCCCEEECCCCCC
YDPIWPRHGIRIIPGPSSLWLDAAGKRLPVPLFPGFDTLGTLEYITKSGHDYTWFVLNAK
CCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEEE
IIEKEFALSGQEQNPDLTGRRLGQLLRSRAHAGPPGPVQAFIDRGVDCVHANSLRELVAA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHH
MNELPDVVPLDYETVAAAVTARDREVVNKYSKDGQITAIRAARRYRGDRFGRVVAPHRLT
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCEECCCCCC
DPKAGPLIAVKLHILTRKTLGGIETDLDARVLKADGTPLAGLYAAGEVAGFGGGGVHGYR
CCCCCCEEEEEEEEEHHHHHCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCEE
ALEGTFLGGCIFSGRAAGRGAAEDIR
EECCCEEEEEEECCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230