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The map label for this gene is fadE4

Identifier: 148659995

GI number: 148659995

Start: 277420

End: 279126

Strand: Direct

Name: fadE4

Synonym: MRA_0239

Alternate gene names: NA

Gene position: 277420-279126 (Clockwise)

Preceding gene: 148659992

Following gene: 148659996

Centisome position: 6.28

GC content: 63.56

Gene sequence:

>1707_bases
ATGCTGCTCAACCCCAACCATTTGACACGCAAATACCCAGACCGTCGCTCCGGGGAGATCATGGCCGCGACGGTGGACTT
CTTCGAGTCCAGGGGGAAGGCCCGGCTCAAGCACGACGACCACGAGCGGATCTGGTACTCGGACTTCCTGGACTTCGTCG
GGCGGGAACGCATCTTTGCTTCCCTACTGACGCCGGCCTCCTATGGCGCCGATGATTGCCGCTGGGACACCTACCGGATC
AGCGAGTTCGCCGAGATCATGGGCTTCTACGGGCTGAGCTACTGGTACCCCTTCCAGGTGACCGCCCTAGGCCTGGGCCC
GATCTGGATGAGCGCCAACGAGGACGCCAAGCGCAAGGCCGCCGCGGGGCTCGAGGCCGGCGAAGTGTTCGCCTTCGGCC
TGTCCGAACAGACCCACGGCGCCGACGTCTATCAGACCGACATGATCCTTACCCCCAGCGACGGCGGCTGGACCGCCAAC
GGCGAGAAGTACTACATCGGCAACGCCAACGTGGCCCGGATGGTCTCCACCTTCGGCAAGATCGCCGGCACCCCAGAAAG
CCAGGAGTACGTCTTCTTCGTCGCCGACTCCCAGCACGAGCGGTATGACCTGATCAAGAATGTGGTGAACTCGCAGAACT
ATGTGGCCAATTACGCGCTGCGCGATTACCCGGTCACCGAGGCCGACATCCTGCATCGTGGCGCCGAAGCCTTCCACGCC
GCCCTCAACACGGTCAACGTCTGCAAGTACAACCTGGGTTGGGGTGCCATCGGAATGTGCACCCACGCCCTCTACGAGTC
GGTCACCCACGCGGCCAACCGTCACCTGTACGGCACTGTGGTGACCGACTTCAGCCACGTGCGGCGGCTGCTCACCGACG
CCTACGTGCGGCTAATTGCGATGAAGCTGGTCGCCAGCCGGGCCAGCGACTACATGCGCAGCGCGTCGGCCGCCGACCGT
CGCTACCTGCTCTACAGCCCGCTGACCAAGGCGAAGGTCACCAGCGAAGGCGAGCGGGTCATCACCGCCCTGTGGGACGT
CATTGCGGCCAAAGGGGTGGAAAAGGACACGTTTTTCGAGACCGTGGCTCGCGAGATTGGCCTGCTGCCCAGGTTGGAAG
GCACCGTGCACATCAACATCGGGCTACTCGGCAAATTCATGCCCAACTACCTGTTCGCTCCCGACTCCACGCTGCCGGTC
ATCCCGCGTCGCGACGACGCCGCCGATGACGCGTTCCTGTTTGCCCAGGGACCCACCGGGGGCTTGGGTAAGGTGCGTTT
CCACGACTGGCGCGCGTCATTTGACACCTGCGCGCATCTGCCTAATGTCGCACTGCTGCGCGAGCAAGTCGACGTGTTCG
CCGAGCTGCTGGCCAGCGCCACCCCGGACGCGGCACAGCAGAAGGATATCGACTTTGCCTTCGGCGTGGGACAACTCTTC
GCGAACGTGCCCTATGCCCAGCTCATTTTGGAGGAGGCCCGGCTATCTGGTGTCGACGAGGCCTTGATCGACGAGATCTT
CGGCGTACTGGTTCGGGACTTCAACACCCATGCCGTCGAGCTGCACGGCAGGTCCGCCACGACAGCCGAACAGGCTCGGT
TCGCCATGCGAATGGTCCGTCGGCCGGTGCACGATCCCGCCCGCTACGACCAGATCTGGAAGGACCACGTGCTCGCGCTC
AACGGCGCATATCAAATGGCACCATAG

Upstream 100 bases:

>100_bases
TGGCACGTCACTGATGCTAGGCCGCAATCGGTGTCTTGCGGGGCCGCAGTGCAGTAGCGTCACCCTCGTCGTTGACCGAA
CCGCTCGGGAGCCAATTCTT

Downstream 100 bases:

>100_bases
TGCGCCGCGTCGAGATCGACGCTGCCGTGTTGCCCACTCGCACTTTCGCGCGCTGGTGTCAATCTCGACGCCAGCCTTGA
CCGTGATGCAGCGCACAGTA

Product: acyl-CoA dehydrogenase FadE4

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: Acyl-CoA Dehydrogenase Domain-Containing Protein; Acyl-CoA Dehydrogenase Domain Protein; Acyl-CoA Dehydrogenase Family Protein; Acyl-CoA Dehydrogenase-Like Protein; Butyryl-CoA Dehydrogenase; Short-Chain Specific Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase Short-Chain Specific; Acyl-CoA Dehydrogenase-Like; Acyl-CoA Dehydrogenase Middle Domain-Containing; Acyl-CoA Dehydrogenase FadE; Glutaryl-CoA Dehydrogenase; Short-Chain Specific Acyl-Coa Dehydrogenase; Acyl-CoA Dehydrogenase C-Terminal Domain Protein; Acyl-Coa Dehydrogenase Oxidoreductase Protein; Cyclohexanecarboxyl-CoA Dehydrogenase

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERIWYSDFLDFVGRERIFASLLTPASYGADDCRWDTYRI
SEFAEIMGFYGLSYWYPFQVTALGLGPIWMSANEDAKRKAAAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTAN
GEKYYIGNANVARMVSTFGKIAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANYALRDYPVTEADILHRGAEAFHA
ALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHLYGTVVTDFSHVRRLLTDAYVRLIAMKLVASRASDYMRSASAADR
RYLLYSPLTKAKVTSEGERVITALWDVIAAKGVEKDTFFETVAREIGLLPRLEGTVHINIGLLGKFMPNYLFAPDSTLPV
IPRRDDAADDAFLFAQGPTGGLGKVRFHDWRASFDTCAHLPNVALLREQVDVFAELLASATPDAAQQKDIDFAFGVGQLF
ANVPYAQLILEEARLSGVDEALIDEIFGVLVRDFNTHAVELHGRSATTAEQARFAMRMVRRPVHDPARYDQIWKDHVLAL
NGAYQMAP

Sequences:

>Translated_568_residues
MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERIWYSDFLDFVGRERIFASLLTPASYGADDCRWDTYRI
SEFAEIMGFYGLSYWYPFQVTALGLGPIWMSANEDAKRKAAAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTAN
GEKYYIGNANVARMVSTFGKIAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANYALRDYPVTEADILHRGAEAFHA
ALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHLYGTVVTDFSHVRRLLTDAYVRLIAMKLVASRASDYMRSASAADR
RYLLYSPLTKAKVTSEGERVITALWDVIAAKGVEKDTFFETVAREIGLLPRLEGTVHINIGLLGKFMPNYLFAPDSTLPV
IPRRDDAADDAFLFAQGPTGGLGKVRFHDWRASFDTCAHLPNVALLREQVDVFAELLASATPDAAQQKDIDFAFGVGQLF
ANVPYAQLILEEARLSGVDEALIDEIFGVLVRDFNTHAVELHGRSATTAEQARFAMRMVRRPVHDPARYDQIWKDHVLAL
NGAYQMAP
>Mature_568_residues
MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERIWYSDFLDFVGRERIFASLLTPASYGADDCRWDTYRI
SEFAEIMGFYGLSYWYPFQVTALGLGPIWMSANEDAKRKAAAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTAN
GEKYYIGNANVARMVSTFGKIAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANYALRDYPVTEADILHRGAEAFHA
ALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHLYGTVVTDFSHVRRLLTDAYVRLIAMKLVASRASDYMRSASAADR
RYLLYSPLTKAKVTSEGERVITALWDVIAAKGVEKDTFFETVAREIGLLPRLEGTVHINIGLLGKFMPNYLFAPDSTLPV
IPRRDDAADDAFLFAQGPTGGLGKVRFHDWRASFDTCAHLPNVALLREQVDVFAELLASATPDAAQQKDIDFAFGVGQLF
ANVPYAQLILEEARLSGVDEALIDEIFGVLVRDFNTHAVELHGRSATTAEQARFAMRMVRRPVHDPARYDQIWKDHVLAL
NGAYQMAP

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.99.3

Molecular weight: Translated: 63495; Mature: 63495

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERIWYSDFLDFVGRERIFA
CCCCCCCHHCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SLLTPASYGADDCRWDTYRISEFAEIMGFYGLSYWYPFQVTALGLGPIWMSANEDAKRKA
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCEEEEEEECCCEEECCCCHHHHHH
AAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTANGEKYYIGNANVARMVSTFGK
HCCCCCCCEEEEECCCCCCCCCEEEECEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHH
IAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANYALRDYPVTEADILHRGAEAFHA
HCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
ALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHLYGTVVTDFSHVRRLLTDAYVRLIA
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
MKLVASRASDYMRSASAADRRYLLYSPLTKAKVTSEGERVITALWDVIAAKGVEKDTFFE
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
TVAREIGLLPRLEGTVHINIGLLGKFMPNYLFAPDSTLPVIPRRDDAADDAFLFAQGPTG
HHHHHHCCCCCCCCEEEEEEEEHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCC
GLGKVRFHDWRASFDTCAHLPNVALLREQVDVFAELLASATPDAAQQKDIDFAFGVGQLF
CCCCEEEEHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHH
ANVPYAQLILEEARLSGVDEALIDEIFGVLVRDFNTHAVELHGRSATTAEQARFAMRMVR
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
RPVHDPARYDQIWKDHVLALNGAYQMAP
CCCCCCHHHHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure
MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERIWYSDFLDFVGRERIFA
CCCCCCCHHCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SLLTPASYGADDCRWDTYRISEFAEIMGFYGLSYWYPFQVTALGLGPIWMSANEDAKRKA
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCEEEEEEECCCEEECCCCHHHHHH
AAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTANGEKYYIGNANVARMVSTFGK
HCCCCCCCEEEEECCCCCCCCCEEEECEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHH
IAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANYALRDYPVTEADILHRGAEAFHA
HCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
ALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHLYGTVVTDFSHVRRLLTDAYVRLIA
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
MKLVASRASDYMRSASAADRRYLLYSPLTKAKVTSEGERVITALWDVIAAKGVEKDTFFE
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
TVAREIGLLPRLEGTVHINIGLLGKFMPNYLFAPDSTLPVIPRRDDAADDAFLFAQGPTG
HHHHHHCCCCCCCCEEEEEEEEHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCC
GLGKVRFHDWRASFDTCAHLPNVALLREQVDVFAELLASATPDAAQQKDIDFAFGVGQLF
CCCCEEEEHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHH
ANVPYAQLILEEARLSGVDEALIDEIFGVLVRDFNTHAVELHGRSATTAEQARFAMRMVR
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
RPVHDPARYDQIWKDHVLALNGAYQMAP
CCCCCCHHHHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA