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The map label for this gene is bdhA [H]

Identifier: 148654177

GI number: 148654177

Start: 2966766

End: 2967830

Strand: Direct

Name: bdhA [H]

Synonym: PsycPRwf_2380

Alternate gene names: 148654177

Gene position: 2966766-2967830 (Clockwise)

Preceding gene: 148654175

Following gene: 148654178

Centisome position: 99.59

GC content: 42.63

Gene sequence:

>1065_bases
ATGAAAGCTGCACGTTTTTATGATAAAGGTGATATTCGTATCGAAGATATCCCAGAACCTACGGTAAAACCTGGTACAGT
TGGCATTAAAGTAGCTTGGTGCGGTATTTGTGGTACTGATTTGCATGAGTTTATGGAAGGGCCTATCTTCATTCCACCCT
GTGGACATCCACATCCCATATCAGGAGAGTCAGCACCTGTTACAATGGGTCATGAGTTTTCTGGTGTGGTTTATGCGGTT
GGTGAAGGGGTGAACGATATTGAAATTGGCCAACATGTTGTAGTTGAGCCTTATATTGTTGCCGATGACGTTCCCACAGG
CCCTGGTGATAATTACCACCTTTCAAAAGACATGAACTTCATTGGTCTTGGCGGCCGCGGTGGTGGCTTGTCAGAAAAAA
TTGCTGTTGAACGTCGCTGGGTGCATCCTATTTCAAATAAAATCCCTTTAGATCAGGCAGCTTTAATTGAGCCTCTTGCA
GTGGGTTACCATGCTTTTATACGTAGCGGTGCACAAAAAGGAGATATCGCTCTAGTTGGTGGTGGTGGGCCTATTGGCTT
GTTGTTATCGGCGGTATTAAAGGCAAAAGGTATCACCGTTATTATGACCGAGCTTAGCGAAAAACGTAAAGAGAAGGCCA
AGGAAAGTGGCGTTGCTGACTACATTTTAGACCCGACCAAGGTTGACTTGAACAAAGAGGTCATGAAAATCACCGAAGAT
CGCGGTGTGGACGTGTCTTTTGAATGTACCAGTGTAAACGCAGTTTTAGATTCTTTAGTTGAGTTGACCAAGCCAGCAGG
ATCGGTAGTTATTGTGTCTATTTGGAGTCATCCCGCCAAAATTGATGTCCACAGTGTGGTTATGAAAGAGCTTGATGTAC
GTGGCACTATTGGTTACGTTAACAATCATCCAGAGACCATAAAACTGGTTGAAGATGGTTTGGTAGATCTTGAGCCGTTT
ATTACTCAACGTATTAAATTAGATGATTTGGTTTCAAAAGGATTTGAGACTTTGATTCATAATAATGACTCCGCTGTTAA
GATTATCGTCAATCCAAACTTATAA

Upstream 100 bases:

>100_bases
TAATAGATATAGAAAAATATTTTTTACTAAAAGTTAATACATATCCTCGTTTATTTCATTTGTTCCATCTCATGTAGATA
ATCTATTAAAGGAAGCTAAT

Downstream 100 bases:

>100_bases
CGGTTGTCTTATCTATCAATGATAGCCTATCAGACTAAACCATAGGGTGCGCAGCAGTGCGCACCTACATGTTCACTCGA
ACTACAATAGCAGAGGGTAA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Acetoin reductase/2,3-butanediol dehydrogenase; AR/BDH [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKAARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPVTMGHEFSGVVYAV
GEGVNDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKDMNFIGLGGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLA
VGYHAFIRSGAQKGDIALVGGGGPIGLLLSAVLKAKGITVIMTELSEKRKEKAKESGVADYILDPTKVDLNKEVMKITED
RGVDVSFECTSVNAVLDSLVELTKPAGSVVIVSIWSHPAKIDVHSVVMKELDVRGTIGYVNNHPETIKLVEDGLVDLEPF
ITQRIKLDDLVSKGFETLIHNNDSAVKIIVNPNL

Sequences:

>Translated_354_residues
MKAARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPVTMGHEFSGVVYAV
GEGVNDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKDMNFIGLGGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLA
VGYHAFIRSGAQKGDIALVGGGGPIGLLLSAVLKAKGITVIMTELSEKRKEKAKESGVADYILDPTKVDLNKEVMKITED
RGVDVSFECTSVNAVLDSLVELTKPAGSVVIVSIWSHPAKIDVHSVVMKELDVRGTIGYVNNHPETIKLVEDGLVDLEPF
ITQRIKLDDLVSKGFETLIHNNDSAVKIIVNPNL
>Mature_354_residues
MKAARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPVTMGHEFSGVVYAV
GEGVNDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKDMNFIGLGGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLA
VGYHAFIRSGAQKGDIALVGGGGPIGLLLSAVLKAKGITVIMTELSEKRKEKAKESGVADYILDPTKVDLNKEVMKITED
RGVDVSFECTSVNAVLDSLVELTKPAGSVVIVSIWSHPAKIDVHSVVMKELDVRGTIGYVNNHPETIKLVEDGLVDLEPF
ITQRIKLDDLVSKGFETLIHNNDSAVKIIVNPNL

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=334, Percent_Identity=30.8383233532934, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI1788073, Length=344, Percent_Identity=27.0348837209302, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790045, Length=333, Percent_Identity=28.5285285285285, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787863, Length=313, Percent_Identity=28.4345047923323, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788407, Length=328, Percent_Identity=28.3536585365854, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI226510992, Length=332, Percent_Identity=26.8072289156627, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788075, Length=374, Percent_Identity=25.9358288770053, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1790718, Length=309, Percent_Identity=25.2427184466019, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562876, Length=331, Percent_Identity=30.2114803625378, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17562878, Length=332, Percent_Identity=28.6144578313253, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319258, Length=378, Percent_Identity=34.9206349206349, Blast_Score=220, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6319257, Length=379, Percent_Identity=32.1899736147757, Blast_Score=193, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6319955, Length=355, Percent_Identity=29.5774647887324, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322619, Length=355, Percent_Identity=29.5774647887324, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6323099, Length=350, Percent_Identity=28.2857142857143, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320033, Length=383, Percent_Identity=26.3707571801567, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17737897, Length=347, Percent_Identity=26.5129682997118, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17137530, Length=348, Percent_Identity=26.1494252873563, Blast_Score=121, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.4 [H]

Molecular weight: Translated: 38083; Mature: 38083

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPI
CCCCCEECCCCEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCEEECCCCCCCCC
SGESAPVTMGHEFSGVVYAVGEGVNDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKDMNF
CCCCCCEEECCCCCCEEEEECCCCCCEECCCEEEECCEEEECCCCCCCCCCEEECCCCCE
IGLGGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLAVGYHAFIRSGAQKGDIALVG
EEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GGGPIGLLLSAVLKAKGITVIMTELSEKRKEKAKESGVADYILDPTKVDLNKEVMKITED
CCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCEEECCCEECCCHHHHHHHHC
RGVDVSFECTSVNAVLDSLVELTKPAGSVVIVSIWSHPAKIDVHSVVMKELDVRGTIGYV
CCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHHHHHHHCCCEEEEEE
NNHPETIKLVEDGLVDLEPFITQRIKLDDLVSKGFETLIHNNDSAVKIIVNPNL
CCCCCEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
>Mature Secondary Structure
MKAARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPI
CCCCCEECCCCEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCEEECCCCCCCCC
SGESAPVTMGHEFSGVVYAVGEGVNDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKDMNF
CCCCCCEEECCCCCCEEEEECCCCCCEECCCEEEECCEEEECCCCCCCCCCEEECCCCCE
IGLGGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLAVGYHAFIRSGAQKGDIALVG
EEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GGGPIGLLLSAVLKAKGITVIMTELSEKRKEKAKESGVADYILDPTKVDLNKEVMKITED
CCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCEEECCCEECCCHHHHHHHHC
RGVDVSFECTSVNAVLDSLVELTKPAGSVVIVSIWSHPAKIDVHSVVMKELDVRGTIGYV
CCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHHHHHHHCCCEEEEEE
NNHPETIKLVEDGLVDLEPFITQRIKLDDLVSKGFETLIHNNDSAVKIIVNPNL
CCCCCEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]