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The map label for this gene is yciK [H]

Identifier: 148653916

GI number: 148653916

Start: 2642392

End: 2643168

Strand: Direct

Name: yciK [H]

Synonym: PsycPRwf_2119

Alternate gene names: 148653916

Gene position: 2642392-2643168 (Clockwise)

Preceding gene: 148653915

Following gene: 148653917

Centisome position: 88.7

GC content: 49.16

Gene sequence:

>777_bases
ATGACTCAACCTGTTTTAACTCATGAAGCGATACGCACCTTTAACCCTGAGCCCAATTGTCTAGAGGGTAAAACCATCTT
AGTCACTGGCGCTGGTGACGGCATTGGCCGCGTGGCTGCTTTAACCTATGCCAAATATGGCGCCACTGTATTACTGCTTG
GCAAAACGTTAAGCAAGCTTGAGGCGGTCTATGATGAAATAGAAGCCGCTGGTGGTAAGCAGCCAGCCATCATGCCGATG
AACCTAGAATCAGCCAGCTATAGCGATATGCAGCAATTGGCCAATCTCATCCAAAGTGAGATTGGTACGCTGCATGGCGT
GTTACACAATGCTGGTATATTGGGCGCCCTAACCCCGCTTGAGATGTATGATGTGGTGACCTTCGAGCAGGTAATGCGAG
TGAATACCACCGCCACCTTTATGCTCACTCAAGTGCTTATGCCCTTGGTCAAATCTGTAGATAACGGCTCATTTGTGTTC
ACAAGCAGCTCAGTGGGTACGCATCCTCGCGCATTCTGGGGCGCGTATGCCTTATCAAAACAGGCGGTGGAAGGCATGAG
TGACATATTCACTCAAGAAACCCAAAATACCACCAGCCTACGCTTTAACTGTATCAATCCTGGCGCCACCCGCACCAACA
TGCGCGCCCATGCCTTTCCCGGCGAGAACCCTATGTCATTAAAGACTGCTGAGGACTTAATGCCGGCATATGTCTGCTTA
ATGAGCGATGCCAGTATTGGGGTTAGAGGTCAAGTTATTGCATTACAACCTAAATAA

Upstream 100 bases:

>100_bases
TATTTATAACTTAGTACGTATAACTTAGTATTTATCACTTAACAGTTATCACTTAGTATTTACCATTTAATAAAACCTCT
ACCAAAATAGTAGTGACCTT

Downstream 100 bases:

>100_bases
AGCTGACACCTGCTAACTGTGTTTTAAACCAGTGCCCTGTCATCAAGGCTAAGTACATCAGGTCGCCTAACTCGTATAGG
TGGCCTTTTTTTGTGACATT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTQPVLTHEAIRTFNPEPNCLEGKTILVTGAGDGIGRVAALTYAKYGATVLLLGKTLSKLEAVYDEIEAAGGKQPAIMPM
NLESASYSDMQQLANLIQSEIGTLHGVLHNAGILGALTPLEMYDVVTFEQVMRVNTTATFMLTQVLMPLVKSVDNGSFVF
TSSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTSLRFNCINPGATRTNMRAHAFPGENPMSLKTAEDLMPAYVCL
MSDASIGVRGQVIALQPK

Sequences:

>Translated_258_residues
MTQPVLTHEAIRTFNPEPNCLEGKTILVTGAGDGIGRVAALTYAKYGATVLLLGKTLSKLEAVYDEIEAAGGKQPAIMPM
NLESASYSDMQQLANLIQSEIGTLHGVLHNAGILGALTPLEMYDVVTFEQVMRVNTTATFMLTQVLMPLVKSVDNGSFVF
TSSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTSLRFNCINPGATRTNMRAHAFPGENPMSLKTAEDLMPAYVCL
MSDASIGVRGQVIALQPK
>Mature_257_residues
TQPVLTHEAIRTFNPEPNCLEGKTILVTGAGDGIGRVAALTYAKYGATVLLLGKTLSKLEAVYDEIEAAGGKQPAIMPMN
LESASYSDMQQLANLIQSEIGTLHGVLHNAGILGALTPLEMYDVVTFEQVMRVNTTATFMLTQVLMPLVKSVDNGSFVFT
SSSVGTHPRAFWGAYALSKQAVEGMSDIFTQETQNTTSLRFNCINPGATRTNMRAHAFPGENPMSLKTAEDLMPAYVCLM
SDASIGVRGQVIALQPK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4557649, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI40548397, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI214010158, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI214010156, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI22758144, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=205, Percent_Identity=25.8536585365854, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=26.6304347826087, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI25282469, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=50.4098360655738, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI87082100, Length=205, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786812, Length=200, Percent_Identity=28, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=26.7716535433071, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=25.3112033195021, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=207, Percent_Identity=28.9855072463768, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=25.9541984732824, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=173, Percent_Identity=30.0578034682081, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=182, Percent_Identity=30.2197802197802, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=173, Percent_Identity=28.9017341040462, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=31.1881188118812, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=173, Percent_Identity=28.9017341040462, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=197, Percent_Identity=27.9187817258883, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=219, Percent_Identity=28.310502283105, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=229, Percent_Identity=28.82096069869, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=241, Percent_Identity=26.9709543568465, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=29.064039408867, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193210355, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=175, Percent_Identity=29.1428571428571, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=29.1457286432161, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=237, Percent_Identity=27.4261603375527, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=202, Percent_Identity=35.6435643564356, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=197, Percent_Identity=32.48730964467, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=196, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357041, Length=198, Percent_Identity=32.8282828282828, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=25.1028806584362, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24643142, Length=202, Percent_Identity=30.1980198019802, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=207, Percent_Identity=27.0531400966184, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24640492, Length=180, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=26.9035532994924, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=203, Percent_Identity=30.0492610837438, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27722; Mature: 27591

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPVLTHEAIRTFNPEPNCLEGKTILVTGAGDGIGRVAALTYAKYGATVLLLGKTLSKL
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEHHHHHHHH
EAVYDEIEAAGGKQPAIMPMNLESASYSDMQQLANLIQSEIGTLHGVLHNAGILGALTPL
HHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHH
EMYDVVTFEQVMRVNTTATFMLTQVLMPLVKSVDNGSFVFTSSSVGTHPRAFWGAYALSK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHH
QAVEGMSDIFTQETQNTTSLRFNCINPGATRTNMRAHAFPGENPMSLKTAEDLMPAYVCL
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
MSDASIGVRGQVIALQPK
HCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
TQPVLTHEAIRTFNPEPNCLEGKTILVTGAGDGIGRVAALTYAKYGATVLLLGKTLSKL
CCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEHHHHHHHH
EAVYDEIEAAGGKQPAIMPMNLESASYSDMQQLANLIQSEIGTLHGVLHNAGILGALTPL
HHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHH
EMYDVVTFEQVMRVNTTATFMLTQVLMPLVKSVDNGSFVFTSSSVGTHPRAFWGAYALSK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHH
QAVEGMSDIFTQETQNTTSLRFNCINPGATRTNMRAHAFPGENPMSLKTAEDLMPAYVCL
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
MSDASIGVRGQVIALQPK
HCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]