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The map label for this gene is icd [H]

Identifier: 148653884

GI number: 148653884

Start: 2604875

End: 2607097

Strand: Direct

Name: icd [H]

Synonym: PsycPRwf_2087

Alternate gene names: 148653884

Gene position: 2604875-2607097 (Clockwise)

Preceding gene: 148653883

Following gene: 148653885

Centisome position: 87.44

GC content: 48.49

Gene sequence:

>2223_bases
ATGTCAAAAATTATATATACCAAAACCGACGAAGCCCCAGCGCTGGCCACGCAGTCATTTTTACCCATTGTACAAGCATT
TACGCATAGTGCCGACATTGAAGTTGAAGTCAGTGATATCTCATTAGCCGCCCGTATTTTGGCACTTTTTCCAGAGTATC
TAAACCCCGAGCAGCAAGTGCCTGATGCACTTACCGAGCTTGGCCAATTAGTGCTAAAGCCTGACGCCAATATCATCAAA
TTACCCAATATCAGCGCCTCTATTCCTCAGCTAAAAGCAGCCATTAAAGAGCTACAAGACAAAGGCTTTGCGGTGCCTGA
CTTCCCAGATACCTCCAGCACCGATAAAGAAAAAGAAGTGCGGGCCCGTTTTGATAAAATCAAAGGCAGTGCGGTAAATC
CGGTACTACGTGAAGGTAACTCAGACAGACGCGCCCCAAAAGCGGTGAAAGCCTATGCCCGAGCCAATCCACATGCCATG
AAGCCTTGGCGCCGTGACTCAAAAACTCATGTATCTACCATGGCACATTGTGACTTCGTTGATGACGAAAAGTCAGTGAC
CATCGATAAAGAAACCAAGTACCGTGTGGTCTATACCGATGAGACCGGTACAGCTACCGAGCTTAAATCGCCTGCTCCGC
TATTAAAGGGGGAGCTGATGGACACCTCTATCTTATGTTTTGATGTGCTAAGCAATTTCTTACAAGAACAAGTGCAAGAT
GCCAAGGCACAGGGCCTGTTATTCTCTATTCATCTAAAAGCGACTATGATGAAAGTGTCTGACCCAATCATCTTTGGTGA
GGCGGTGCGAGTTTATTTTAAAGACTTGTTTGCCAAACACGGTGAGACTTTTGACAAGCTCGGTGTCAACGTCAACAATG
GCTTTGCCCAGTTGCTGTCCAAGATTCAAGAGCTGCCAGATGATCAGCGTCAACAGATAGAGGCGGATATTCAACAGGTA
TATGACACCAATCCGCCACTGGCCATGGTCGATTCAGACAAAGGCATTACCAACTTGCATGTGCCAAGTGATGTCATTGT
CGATGCCTCTATGCCAGCGATGATCCGTAACGGTGGTCAAATGTGGGGCCCTGATGGCAAGCTACATGATGTGAATGCAG
TAATCCCCGACAGCAGTTATGCCGCTCTTTATGATGAGACCATCCGCTTTTGTAAAGAGCATGGTGCCTTTGACCCCACC
ACCATGGGCACTGTACCCAATATTGGCCTTATGGCTCAAAAAGCCGAAGAGTATGGCTCGCATGACACCACTTTTCAGAT
GCCAGGCAAAGGAAAAATCCAAGTCATCGATGCCGATGGCAACGTGCTGACTGAGCATGCGGTCAAAAAAGATGACATCT
GGCGCATGAACCGTGTCAAAGATGCCCCTATCCAAGACTGGGTAAAACTTGCAGTGACCCGTGCCCGAGCCAGCGGCATG
CCGGCCGTTTTCTGGCTGGATAAAAACCGGGCTCACCACGCCGCCTTAATCGAAAAAGTCGAGTTGTACCTAAAAGACCA
TGACACCGAAGGCTTAGAAATTCATATCATGCCCATTCGTGAAGCAACCCGATTTACGCTTGAGCGTCTGATCGCTGGCA
AGGATACGCTGTCAGTCACCGGCAACGTATTGCGTGATTATCTGACCGATTTATTTCCCATCCTTGAGCTGGGTACCAGT
GCTAAGATGCTATCTATCGTGCCGCTTATGAACGGTGGCGGCCTGTTTGAAACCGGTGCCGGTGGTTCAGCGCCCAAACA
TGTGCAGCAGCTGCTGGAGCAAAATCATCTACGCTGGGATTCACTGGGAGAGTTTTTGGCATTGACTGTGTCACTTGAGC
ACGAAGCTGAGCATGGCACCGCACAAAACCCAAAAGCGCAAATCCTAGCCGATACTTTAAGCGATGCCACCGAGAAGCTC
CTGCTAAACAACAAGTCACCTTCACGTAAAGTGGGTGAGTTGGACAACCGCGGCAGCCATTTTTACTTGGCCATGTACTG
GGCTCAAGCATTGGCCAAGCAAGACCAAGATGCCAGCCTACAACAAAGATTTGCGCCACTGGCTAAAGCACTTGCCGATA
ATGAGGATACTATCGTCAAAGAGCTTAATGAGGTGCAAGGTCATCAAGTGGACATTGAGGGTTACTATCTGCCCAATGAT
GAGGTTGTAAAGCAGGTGATGCGCCCAAGCCAAACCTTCAATAAGATTTTAGCTGCGCTATAA

Upstream 100 bases:

>100_bases
AACCCCAAAAACAAATCTTTTTTTGAGCCGTCAGAATATCTTTCGCCATAACAAAACACGGCCTCAGTCATAAAACAATA
AAAAAGGAATGCATACCATC

Downstream 100 bases:

>100_bases
GCACAAGCCATGAAGCCTCATCTGGCTGACATGGCTTGCTACATCGCCCGTTTGATTTTATGTTAATACCTCAGTAGCTT
AAACTATTGAGGTATTTTAT

Product: isocitrate dehydrogenase

Products: NA

Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]

Number of amino acids: Translated: 740; Mature: 739

Protein sequence:

>740_residues
MSKIIYTKTDEAPALATQSFLPIVQAFTHSADIEVEVSDISLAARILALFPEYLNPEQQVPDALTELGQLVLKPDANIIK
LPNISASIPQLKAAIKELQDKGFAVPDFPDTSSTDKEKEVRARFDKIKGSAVNPVLREGNSDRRAPKAVKAYARANPHAM
KPWRRDSKTHVSTMAHCDFVDDEKSVTIDKETKYRVVYTDETGTATELKSPAPLLKGELMDTSILCFDVLSNFLQEQVQD
AKAQGLLFSIHLKATMMKVSDPIIFGEAVRVYFKDLFAKHGETFDKLGVNVNNGFAQLLSKIQELPDDQRQQIEADIQQV
YDTNPPLAMVDSDKGITNLHVPSDVIVDASMPAMIRNGGQMWGPDGKLHDVNAVIPDSSYAALYDETIRFCKEHGAFDPT
TMGTVPNIGLMAQKAEEYGSHDTTFQMPGKGKIQVIDADGNVLTEHAVKKDDIWRMNRVKDAPIQDWVKLAVTRARASGM
PAVFWLDKNRAHHAALIEKVELYLKDHDTEGLEIHIMPIREATRFTLERLIAGKDTLSVTGNVLRDYLTDLFPILELGTS
AKMLSIVPLMNGGGLFETGAGGSAPKHVQQLLEQNHLRWDSLGEFLALTVSLEHEAEHGTAQNPKAQILADTLSDATEKL
LLNNKSPSRKVGELDNRGSHFYLAMYWAQALAKQDQDASLQQRFAPLAKALADNEDTIVKELNEVQGHQVDIEGYYLPND
EVVKQVMRPSQTFNKILAAL

Sequences:

>Translated_740_residues
MSKIIYTKTDEAPALATQSFLPIVQAFTHSADIEVEVSDISLAARILALFPEYLNPEQQVPDALTELGQLVLKPDANIIK
LPNISASIPQLKAAIKELQDKGFAVPDFPDTSSTDKEKEVRARFDKIKGSAVNPVLREGNSDRRAPKAVKAYARANPHAM
KPWRRDSKTHVSTMAHCDFVDDEKSVTIDKETKYRVVYTDETGTATELKSPAPLLKGELMDTSILCFDVLSNFLQEQVQD
AKAQGLLFSIHLKATMMKVSDPIIFGEAVRVYFKDLFAKHGETFDKLGVNVNNGFAQLLSKIQELPDDQRQQIEADIQQV
YDTNPPLAMVDSDKGITNLHVPSDVIVDASMPAMIRNGGQMWGPDGKLHDVNAVIPDSSYAALYDETIRFCKEHGAFDPT
TMGTVPNIGLMAQKAEEYGSHDTTFQMPGKGKIQVIDADGNVLTEHAVKKDDIWRMNRVKDAPIQDWVKLAVTRARASGM
PAVFWLDKNRAHHAALIEKVELYLKDHDTEGLEIHIMPIREATRFTLERLIAGKDTLSVTGNVLRDYLTDLFPILELGTS
AKMLSIVPLMNGGGLFETGAGGSAPKHVQQLLEQNHLRWDSLGEFLALTVSLEHEAEHGTAQNPKAQILADTLSDATEKL
LLNNKSPSRKVGELDNRGSHFYLAMYWAQALAKQDQDASLQQRFAPLAKALADNEDTIVKELNEVQGHQVDIEGYYLPND
EVVKQVMRPSQTFNKILAAL
>Mature_739_residues
SKIIYTKTDEAPALATQSFLPIVQAFTHSADIEVEVSDISLAARILALFPEYLNPEQQVPDALTELGQLVLKPDANIIKL
PNISASIPQLKAAIKELQDKGFAVPDFPDTSSTDKEKEVRARFDKIKGSAVNPVLREGNSDRRAPKAVKAYARANPHAMK
PWRRDSKTHVSTMAHCDFVDDEKSVTIDKETKYRVVYTDETGTATELKSPAPLLKGELMDTSILCFDVLSNFLQEQVQDA
KAQGLLFSIHLKATMMKVSDPIIFGEAVRVYFKDLFAKHGETFDKLGVNVNNGFAQLLSKIQELPDDQRQQIEADIQQVY
DTNPPLAMVDSDKGITNLHVPSDVIVDASMPAMIRNGGQMWGPDGKLHDVNAVIPDSSYAALYDETIRFCKEHGAFDPTT
MGTVPNIGLMAQKAEEYGSHDTTFQMPGKGKIQVIDADGNVLTEHAVKKDDIWRMNRVKDAPIQDWVKLAVTRARASGMP
AVFWLDKNRAHHAALIEKVELYLKDHDTEGLEIHIMPIREATRFTLERLIAGKDTLSVTGNVLRDYLTDLFPILELGTSA
KMLSIVPLMNGGGLFETGAGGSAPKHVQQLLEQNHLRWDSLGEFLALTVSLEHEAEHGTAQNPKAQILADTLSDATEKLL
LNNKSPSRKVGELDNRGSHFYLAMYWAQALAKQDQDASLQQRFAPLAKALADNEDTIVKELNEVQGHQVDIEGYYLPNDE
VVKQVMRPSQTFNKILAAL

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 82035; Mature: 81904

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIYTKTDEAPALATQSFLPIVQAFTHSADIEVEVSDISLAARILALFPEYLNPEQQV
CCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHH
PDALTELGQLVLKPDANIIKLPNISASIPQLKAAIKELQDKGFAVPDFPDTSSTDKEKEV
HHHHHHHHHEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
RARFDKIKGSAVNPVLREGNSDRRAPKAVKAYARANPHAMKPWRRDSKTHVSTMAHCDFV
HHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCC
DDEKSVTIDKETKYRVVYTDETGTATELKSPAPLLKGELMDTSILCFDVLSNFLQEQVQD
CCCCCEEEECCCEEEEEEECCCCCHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
AKAQGLLFSIHLKATMMKVSDPIIFGEAVRVYFKDLFAKHGETFDKLGVNVNNGFAQLLS
HHHCCEEEEEEEHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
KIQELPDDQRQQIEADIQQVYDTNPPLAMVDSDKGITNLHVPSDVIVDASMPAMIRNGGQ
HHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCEEECCCCCHHHHCCCC
MWGPDGKLHDVNAVIPDSSYAALYDETIRFCKEHGAFDPTTMGTVPNIGLMAQKAEEYGS
CCCCCCCEEECEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCC
HDTTFQMPGKGKIQVIDADGNVLTEHAVKKDDIWRMNRVKDAPIQDWVKLAVTRARASGM
CCCEEECCCCCEEEEEECCCCEEHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCC
PAVFWLDKNRAHHAALIEKVELYLKDHDTEGLEIHIMPIREATRFTLERLIAGKDTLSVT
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHH
GNVLRDYLTDLFPILELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQLLEQNHLRWD
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCHH
SLGEFLALTVSLEHEAEHGTAQNPKAQILADTLSDATEKLLLNNKSPSRKVGELDNRGSH
HHHCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCE
FYLAMYWAQALAKQDQDASLQQRFAPLAKALADNEDTIVKELNEVQGHQVDIEGYYLPND
EEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECCCH
EVVKQVMRPSQTFNKILAAL
HHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
SKIIYTKTDEAPALATQSFLPIVQAFTHSADIEVEVSDISLAARILALFPEYLNPEQQV
CCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHH
PDALTELGQLVLKPDANIIKLPNISASIPQLKAAIKELQDKGFAVPDFPDTSSTDKEKEV
HHHHHHHHHEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
RARFDKIKGSAVNPVLREGNSDRRAPKAVKAYARANPHAMKPWRRDSKTHVSTMAHCDFV
HHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCC
DDEKSVTIDKETKYRVVYTDETGTATELKSPAPLLKGELMDTSILCFDVLSNFLQEQVQD
CCCCCEEEECCCEEEEEEECCCCCHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
AKAQGLLFSIHLKATMMKVSDPIIFGEAVRVYFKDLFAKHGETFDKLGVNVNNGFAQLLS
HHHCCEEEEEEEHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
KIQELPDDQRQQIEADIQQVYDTNPPLAMVDSDKGITNLHVPSDVIVDASMPAMIRNGGQ
HHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCEEECCCCCHHHHCCCC
MWGPDGKLHDVNAVIPDSSYAALYDETIRFCKEHGAFDPTTMGTVPNIGLMAQKAEEYGS
CCCCCCCEEECEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCC
HDTTFQMPGKGKIQVIDADGNVLTEHAVKKDDIWRMNRVKDAPIQDWVKLAVTRARASGM
CCCEEECCCCCEEEEEECCCCEEHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCC
PAVFWLDKNRAHHAALIEKVELYLKDHDTEGLEIHIMPIREATRFTLERLIAGKDTLSVT
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHH
GNVLRDYLTDLFPILELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQLLEQNHLRWD
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCHH
SLGEFLALTVSLEHEAEHGTAQNPKAQILADTLSDATEKLLLNNKSPSRKVGELDNRGSH
HHHCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCE
FYLAMYWAQALAKQDQDASLQQRFAPLAKALADNEDTIVKELNEVQGHQVDIEGYYLPND
EEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECCCH
EVVKQVMRPSQTFNKILAAL
HHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12005040; 4149369; 12467571 [H]