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The map label for this gene is rluB [H]

Identifier: 148653754

GI number: 148653754

Start: 2440031

End: 2441068

Strand: Direct

Name: rluB [H]

Synonym: PsycPRwf_1957

Alternate gene names: 148653754

Gene position: 2440031-2441068 (Clockwise)

Preceding gene: 148653753

Following gene: 148653757

Centisome position: 81.91

GC content: 48.94

Gene sequence:

>1038_bases
ATGCCTCAGTCAAATCAAAACCCCGAAACCCAAGCTCCCGATACACTACAAAGCGATGTTACCATTGACCACAATGGCGA
TTATCAGTTCGCAGCGCCTACCACTTCTGCCAGCACAGCCGGCACCGAAAAGCTACAAAAAGCATTGGCTCGTATGGGCC
TAGGCTCACGTCGCCAAATGGAAGAGGTCATTAAAGCAGGCCGTGTTTCTATTAACCAAAAACCTGCCAGCATCGGTGAT
CGTGTCGAACAAGGCGATGAAATTCGTGTTGATGGCCGCCTAATTAAATACAAATCTGAGCGTGAAAAACGCCGCCGCGT
TTTGGCCTATTACAAGCCAGAAGGTGAGATCTGTTCTGCCAATGATCCAGAAGGTCGTACCACGGTATTTGAGCGTCTGC
CTAAGCTGACTCATGATCGCTGGATTATGGTGGGTCGTCTAGACATTAACTCTACGGGCTTATTATTATTCACCAACGAT
GGCGAATTGGCGCACCGTTTAATGCACCCATCAAACGAGATTGTACGTGAATATGCGGTACGTATCTTAGGCGAGCTGAC
CCCTGAAATGATGCGCAATTTAACCGATGGCGTTATGCTTGAGGATGGCCTTGCTAAGTTTGAAGACATCAAACAAGGCG
GCGGTGAAGGCGTAAACAAATGGTATCACGTGAAGCTAAAAGAGGGCCGTAACCGTGAAGTACGCCGTCTGATTGAATCA
CAAGGCCTAAAAGTAAGCCGTCTACTGCGTACCAGCTATGGCTCAGTGGATCTACCCAAGGAGCTACGTACCGGCCGCTT
TATCGAGCTTGATAGAAAAGACATTCACCGTCTGATTGATCTGGTCGGCATACGTCCTCGTGAAGACATGGGTGTGCATG
GTAAAGCCAAAGAGAAAAAAGAGCGCTTCCAGAAAAAACCGATGAAAGCCCGCACCATTCGTACCAGCTCTCGCAGCGGT
CGTGCCAGCACCTCAACTGGCAAAAATACCAGTGCCACTCGTGGTAGAGATACTGGTAATAGAGGCTCTAAGCGTTAA

Upstream 100 bases:

>100_bases
ACAATAGCCACAATATCACGTACAATAGCTGCGTTAATTCTAAAAACTGAATAACCTACATTGTGAAATGTAGTCACCCA
CCGATTCCAGGATGCATACC

Downstream 100 bases:

>100_bases
ATACGACTTATTTATAGCGCATTTATATAAAAAGCCCTTAGTAGATGAACTGAACCCCATAAGTTGGACACAACTTATGG
GGTATTTTTGTCAGCTTCGG

Product: RNA-binding S4 domain-containing protein

Products: NA

Alternate protein names: rRNA pseudouridylate synthase B; rRNA-uridine isomerase B [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPQSNQNPETQAPDTLQSDVTIDHNGDYQFAAPTTSASTAGTEKLQKALARMGLGSRRQMEEVIKAGRVSINQKPASIGD
RVEQGDEIRVDGRLIKYKSEREKRRRVLAYYKPEGEICSANDPEGRTTVFERLPKLTHDRWIMVGRLDINSTGLLLFTND
GELAHRLMHPSNEIVREYAVRILGELTPEMMRNLTDGVMLEDGLAKFEDIKQGGGEGVNKWYHVKLKEGRNREVRRLIES
QGLKVSRLLRTSYGSVDLPKELRTGRFIELDRKDIHRLIDLVGIRPREDMGVHGKAKEKKERFQKKPMKARTIRTSSRSG
RASTSTGKNTSATRGRDTGNRGSKR

Sequences:

>Translated_345_residues
MPQSNQNPETQAPDTLQSDVTIDHNGDYQFAAPTTSASTAGTEKLQKALARMGLGSRRQMEEVIKAGRVSINQKPASIGD
RVEQGDEIRVDGRLIKYKSEREKRRRVLAYYKPEGEICSANDPEGRTTVFERLPKLTHDRWIMVGRLDINSTGLLLFTND
GELAHRLMHPSNEIVREYAVRILGELTPEMMRNLTDGVMLEDGLAKFEDIKQGGGEGVNKWYHVKLKEGRNREVRRLIES
QGLKVSRLLRTSYGSVDLPKELRTGRFIELDRKDIHRLIDLVGIRPREDMGVHGKAKEKKERFQKKPMKARTIRTSSRSG
RASTSTGKNTSATRGRDTGNRGSKR
>Mature_344_residues
PQSNQNPETQAPDTLQSDVTIDHNGDYQFAAPTTSASTAGTEKLQKALARMGLGSRRQMEEVIKAGRVSINQKPASIGDR
VEQGDEIRVDGRLIKYKSEREKRRRVLAYYKPEGEICSANDPEGRTTVFERLPKLTHDRWIMVGRLDINSTGLLLFTNDG
ELAHRLMHPSNEIVREYAVRILGELTPEMMRNLTDGVMLEDGLAKFEDIKQGGGEGVNKWYHVKLKEGRNREVRRLIESQ
GLKVSRLLRTSYGSVDLPKELRTGRFIELDRKDIHRLIDLVGIRPREDMGVHGKAKEKKERFQKKPMKARTIRTSSRSGR
ASTSTGKNTSATRGRDTGNRGSKR

Specific function: Responsible for synthesis of pseudouridine from uracil- 2605 in 23S ribosomal RNA [H]

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=293, Percent_Identity=53.9249146757679, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1790453, Length=217, Percent_Identity=32.258064516129, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788510, Length=221, Percent_Identity=25.7918552036199, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081838, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 39021; Mature: 38890

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: PS50889 S4 ; PS00070 ALDEHYDE_DEHYDR_CYS ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSNQNPETQAPDTLQSDVTIDHNGDYQFAAPTTSASTAGTEKLQKALARMGLGSRRQM
CCCCCCCCCCCCCCCHHCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHH
EEVIKAGRVSINQKPASIGDRVEQGDEIRVDGRLIKYKSEREKRRRVLAYYKPEGEICSA
HHHHHHCCCCCCCCCHHHHHHHHCCCEEEECCEEEEEHHHHHHHCCEEEEECCCCCEECC
NDPEGRTTVFERLPKLTHDRWIMVGRLDINSTGLLLFTNDGELAHRLMHPSNEIVREYAV
CCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECCHHHHHHHHCCCHHHHHHHHH
RILGELTPEMMRNLTDGVMLEDGLAKFEDIKQGGGEGVNKWYHVKLKEGRNREVRRLIES
HHHHHCCHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHH
QGLKVSRLLRTSYGSVDLPKELRTGRFIELDRKDIHRLIDLVGIRPREDMGVHGKAKEKK
CCCHHHHHHHHCCCCCCCCHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
ERFQKKPMKARTIRTSSRSGRASTSTGKNTSATRGRDTGNRGSKR
HHHHHCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQSNQNPETQAPDTLQSDVTIDHNGDYQFAAPTTSASTAGTEKLQKALARMGLGSRRQM
CCCCCCCCCCCCCCHHCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHH
EEVIKAGRVSINQKPASIGDRVEQGDEIRVDGRLIKYKSEREKRRRVLAYYKPEGEICSA
HHHHHHCCCCCCCCCHHHHHHHHCCCEEEECCEEEEEHHHHHHHCCEEEEECCCCCEECC
NDPEGRTTVFERLPKLTHDRWIMVGRLDINSTGLLLFTNDGELAHRLMHPSNEIVREYAV
CCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEECCHHHHHHHHCCCHHHHHHHHH
RILGELTPEMMRNLTDGVMLEDGLAKFEDIKQGGGEGVNKWYHVKLKEGRNREVRRLIES
HHHHHCCHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHH
QGLKVSRLLRTSYGSVDLPKELRTGRFIELDRKDIHRLIDLVGIRPREDMGVHGKAKEKK
CCCHHHHHHHHCCCCCCCCHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
ERFQKKPMKARTIRTSSRSGRASTSTGKNTSATRGRDTGNRGSKR
HHHHHCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]