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The map label for this gene is lspA [H]

Identifier: 148653690

GI number: 148653690

Start: 2352561

End: 2353169

Strand: Direct

Name: lspA [H]

Synonym: PsycPRwf_1893

Alternate gene names: 148653690

Gene position: 2352561-2353169 (Clockwise)

Preceding gene: 148653689

Following gene: 148653692

Centisome position: 78.97

GC content: 48.44

Gene sequence:

>609_bases
ATGCCTAAGACTTCAGGCAATACCCAGTCAAGCTCTGATACCGTAGAGACCAAGCCGGCCTATGCGACAGCCACGCCAGG
GCTTAGCAAGCGCCCCAGACTGATTGCCAATGGGCCTCGAGCGCTGATGTGGTATTTGTTATCGCTACTGGTTATTGGTC
TTGATCAGTGGACCAAGTGGATTGCCAATACCAAGCTTAATTTCCATGAGCCAGTACCCGTTATTGAGCCGATTTTAAAT
TGGACTTTGGCGTATAACTATGGCGCCGCTTTTAGCTTTTTGGCCGATCAAGGCGGCTGGCAAAAATGGTTTTTTGCTGG
CTTGTCGTTGGCGATGTCTGTGTTTTTGGTGGTTTATCTAACCCGCGCCCCGCGCCAAGCCAAGCTGCTTAACGTGGGTC
TGGCACTTATCTTAGGCGGTGCTATTGGTAATTTAATTGATCGGGTGCGCATCGGTAAGGTCATTGACTTTATCCATGTG
CATTATGCTGATGTGTGGCATTACCCCATCTTTAACATCGCCGATATTGCAATTTGTGTGGGTGTGGCCATCGTGGTGAT
AGATATGCTATTTTTAGAGGGCAAACGCAACGCCAAATATCAGGCTTAA

Upstream 100 bases:

>100_bases
TGCTGGCACGTGCGTGATGATGTGGGCACCGACCCAAGTCATCCTGAAATTTGTACCCGCTGCGTCAGCAACATCCAAGG
TCCAGGCGAGGTTCGTCATT

Downstream 100 bases:

>100_bases
GCCCAGCTACGTTGCAATAATTAGTTAGCTTTATTTACGCTTTAGTTTTTACCAAAAGCAGCAAGCCCGCTTATAGCGGG
CTTGCTGCTTTTTGCTGCAA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPKTSGNTQSSSDTVETKPAYATATPGLSKRPRLIANGPRALMWYLLSLLVIGLDQWTKWIANTKLNFHEPVPVIEPILN
WTLAYNYGAAFSFLADQGGWQKWFFAGLSLAMSVFLVVYLTRAPRQAKLLNVGLALILGGAIGNLIDRVRIGKVIDFIHV
HYADVWHYPIFNIADIAICVGVAIVVIDMLFLEGKRNAKYQA

Sequences:

>Translated_202_residues
MPKTSGNTQSSSDTVETKPAYATATPGLSKRPRLIANGPRALMWYLLSLLVIGLDQWTKWIANTKLNFHEPVPVIEPILN
WTLAYNYGAAFSFLADQGGWQKWFFAGLSLAMSVFLVVYLTRAPRQAKLLNVGLALILGGAIGNLIDRVRIGKVIDFIHV
HYADVWHYPIFNIADIAICVGVAIVVIDMLFLEGKRNAKYQA
>Mature_201_residues
PKTSGNTQSSSDTVETKPAYATATPGLSKRPRLIANGPRALMWYLLSLLVIGLDQWTKWIANTKLNFHEPVPVIEPILNW
TLAYNYGAAFSFLADQGGWQKWFFAGLSLAMSVFLVVYLTRAPRQAKLLNVGLALILGGAIGNLIDRVRIGKVIDFIHVH
YADVWHYPIFNIADIAICVGVAIVVIDMLFLEGKRNAKYQA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=148, Percent_Identity=46.6216216216216, Blast_Score=131, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 22418; Mature: 22286

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTSGNTQSSSDTVETKPAYATATPGLSKRPRLIANGPRALMWYLLSLLVIGLDQWTKW
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
IANTKLNFHEPVPVIEPILNWTLAYNYGAAFSFLADQGGWQKWFFAGLSLAMSVFLVVYL
HHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TRAPRQAKLLNVGLALILGGAIGNLIDRVRIGKVIDFIHVHYADVWHYPIFNIADIAICV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVAIVVIDMLFLEGKRNAKYQA
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PKTSGNTQSSSDTVETKPAYATATPGLSKRPRLIANGPRALMWYLLSLLVIGLDQWTKW
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
IANTKLNFHEPVPVIEPILNWTLAYNYGAAFSFLADQGGWQKWFFAGLSLAMSVFLVVYL
HHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TRAPRQAKLLNVGLALILGGAIGNLIDRVRIGKVIDFIHVHYADVWHYPIFNIADIAICV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVAIVVIDMLFLEGKRNAKYQA
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA