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The map label for this gene is fbp

Identifier: 148653654

GI number: 148653654

Start: 2310955

End: 2311959

Strand: Direct

Name: fbp

Synonym: PsycPRwf_1857

Alternate gene names: 148653654

Gene position: 2310955-2311959 (Clockwise)

Preceding gene: 148653650

Following gene: 148653655

Centisome position: 77.58

GC content: 48.76

Gene sequence:

>1005_bases
ATGACCAGCCTTACCCAGTACTTTGAGCAACACCCTAAGCTTCCGCAAACCCAAGCGGTGATAGATGTTATCACCACCAT
CACCAATGTCGGCAAACAAATCACGGACCTGCTACGTCAAGGTGCTCTAGCAGACATCCATGGTGAAGCCGGTGCTGAGA
ACGTCCAAGGCGAGCAACAAAAGAAGCTAGACGTTATTGCCAATGACTTATTGCTAGAGGCGCTGACGGCAAATAAACAC
TGCGCCGGCGTGGCCAGTGAAGAGCTAGATGATGCCACTCCTGCCAATGAGTCAGGCGAGCTGTTAGTATTATTCGACCC
ACTGGATGGCTCATCAAATATTGATATTAACATGCCTACCGGTACTATTTTCTCTATCTTACCGCACAATAACAAAGGCC
AAGCAGCACAAAACGCTGACTTCTTACAAAAAGGTACTGAGCAATTGGCGGCAGGTTATCTGCTGTACGGCTCATCAGCG
ATGCTTGCCTTTACTTTATCTGAGTCACTAGACGCCAATAATGAGGGTGTGGTTATGTTTAGCTTAAACCCAAGCACGGG
GGAGTTTGAGCTGGTTAAAAACAACATCACTATCGATGCAGACACCAAAGAATACGCCATTAATGCCTCAAATGCTCGTC
ACTGGCTACCACCCATGCAGCAGTATATTAATGAGCTATTGGCAGGCAGCAGCGGACCACGCGGTAAGAACTTCAATACC
CGCTGGGTTGCGGCCATGGTAGGCGATGTACACCGCATCTTATGCCGCGGCGGTATCTTCATTTACCCCAAAGACACCAA
AGATCCCAATAAAGCGGGCAAACTACGCTTAATGTATGAAGCCAATCCCATGAGCCTGCTGATTGAACGTGCAGGTGGTG
CTTCAACCGATGCCCTAAATCGTATTATGGATTGTGAGCCTACCGATATCCACCAACGCGTGGCGGTGGTGCTGGGCGCA
AAAAACGAAGTTGAGTATGTCCAAAAGCTACATCAGCAGGCCTAA

Upstream 100 bases:

>100_bases
TTCAATGCGGCCTATGTATAGATGAGCTTGTATAAATTACCTATCGCCTTTTATATTAGCCGATTATTCCCTTGATATTG
TCCCATTTTTAGGAGTTTTT

Downstream 100 bases:

>100_bases
TAAACCGAGCGCTATTTGCTATAAGCGCCCTATGAAAAGACCAAACTCAGGCAGTTTGGTCTTTTTATTTTCGTGTGAGT
AACTAAATATCGAGCAAGGT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTSLTQYFEQHPKLPQTQAVIDVITTITNVGKQITDLLRQGALADIHGEAGAENVQGEQQKKLDVIANDLLLEALTANKH
CAGVASEELDDATPANESGELLVLFDPLDGSSNIDINMPTGTIFSILPHNNKGQAAQNADFLQKGTEQLAAGYLLYGSSA
MLAFTLSESLDANNEGVVMFSLNPSTGEFELVKNNITIDADTKEYAINASNARHWLPPMQQYINELLAGSSGPRGKNFNT
RWVAAMVGDVHRILCRGGIFIYPKDTKDPNKAGKLRLMYEANPMSLLIERAGGASTDALNRIMDCEPTDIHQRVAVVLGA
KNEVEYVQKLHQQA

Sequences:

>Translated_334_residues
MTSLTQYFEQHPKLPQTQAVIDVITTITNVGKQITDLLRQGALADIHGEAGAENVQGEQQKKLDVIANDLLLEALTANKH
CAGVASEELDDATPANESGELLVLFDPLDGSSNIDINMPTGTIFSILPHNNKGQAAQNADFLQKGTEQLAAGYLLYGSSA
MLAFTLSESLDANNEGVVMFSLNPSTGEFELVKNNITIDADTKEYAINASNARHWLPPMQQYINELLAGSSGPRGKNFNT
RWVAAMVGDVHRILCRGGIFIYPKDTKDPNKAGKLRLMYEANPMSLLIERAGGASTDALNRIMDCEPTDIHQRVAVVLGA
KNEVEYVQKLHQQA
>Mature_333_residues
TSLTQYFEQHPKLPQTQAVIDVITTITNVGKQITDLLRQGALADIHGEAGAENVQGEQQKKLDVIANDLLLEALTANKHC
AGVASEELDDATPANESGELLVLFDPLDGSSNIDINMPTGTIFSILPHNNKGQAAQNADFLQKGTEQLAAGYLLYGSSAM
LAFTLSESLDANNEGVVMFSLNPSTGEFELVKNNITIDADTKEYAINASNARHWLPPMQQYINELLAGSSGPRGKNFNTR
WVAAMVGDVHRILCRGGIFIYPKDTKDPNKAGKLRLMYEANPMSLLIERAGGASTDALNRIMDCEPTDIHQRVAVVLGAK
NEVEYVQKLHQQA

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=338, Percent_Identity=38.1656804733728, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI16579888, Length=338, Percent_Identity=38.1656804733728, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI22907028, Length=330, Percent_Identity=36.969696969697, Blast_Score=207, Evalue=8e-54,
Organism=Escherichia coli, GI1790679, Length=335, Percent_Identity=38.5074626865672, Blast_Score=219, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17508131, Length=296, Percent_Identity=41.8918918918919, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323409, Length=300, Percent_Identity=38, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI45550998, Length=328, Percent_Identity=37.1951219512195, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI19921562, Length=328, Percent_Identity=37.1951219512195, Blast_Score=194, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_PSYWF (A5WGK6)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001280747.1
- ProteinModelPortal:   A5WGK6
- SMR:   A5WGK6
- STRING:   A5WGK6
- GeneID:   5205869
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_1857
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- ProtClustDB:   PRK09293
- BioCyc:   PSP56811:PSYCPRWF_1857-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36304; Mature: 36173

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00124 FBPASE

Important sites: BINDING 208-208 BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLTQYFEQHPKLPQTQAVIDVITTITNVGKQITDLLRQGALADIHGEAGAENVQGEQQ
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHH
KKLDVIANDLLLEALTANKHCAGVASEELDDATPANESGELLVLFDPLDGSSNIDINMPT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEECCC
GTIFSILPHNNKGQAAQNADFLQKGTEQLAAGYLLYGSSAMLAFTLSESLDANNEGVVMF
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEEEEHHHCCCCCCCEEEE
SLNPSTGEFELVKNNITIDADTKEYAINASNARHWLPPMQQYINELLAGSSGPRGKNFNT
EECCCCCCEEEEECCEEEECCCHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCH
RWVAAMVGDVHRILCRGGIFIYPKDTKDPNKAGKLRLMYEANPMSLLIERAGGASTDALN
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCHHEEEECCCCCCHHHHH
RIMDCEPTDIHQRVAVVLGAKNEVEYVQKLHQQA
HHHCCCCCHHHHHHHHEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TSLTQYFEQHPKLPQTQAVIDVITTITNVGKQITDLLRQGALADIHGEAGAENVQGEQQ
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHH
KKLDVIANDLLLEALTANKHCAGVASEELDDATPANESGELLVLFDPLDGSSNIDINMPT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEECCC
GTIFSILPHNNKGQAAQNADFLQKGTEQLAAGYLLYGSSAMLAFTLSESLDANNEGVVMF
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEEEEHHHCCCCCCCEEEE
SLNPSTGEFELVKNNITIDADTKEYAINASNARHWLPPMQQYINELLAGSSGPRGKNFNT
EECCCCCCEEEEECCEEEECCCHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCH
RWVAAMVGDVHRILCRGGIFIYPKDTKDPNKAGKLRLMYEANPMSLLIERAGGASTDALN
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCHHEEEECCCCCCHHHHH
RIMDCEPTDIHQRVAVVLGAKNEVEYVQKLHQQA
HHHCCCCCHHHHHHHHEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA