Click here to switch to the map view.

The map label for this gene is aspA [H]

Identifier: 148653343

GI number: 148653343

Start: 1890237

End: 1891649

Strand: Direct

Name: aspA [H]

Synonym: PsycPRwf_1545

Alternate gene names: 148653343

Gene position: 1890237-1891649 (Clockwise)

Preceding gene: 148653342

Following gene: 148653344

Centisome position: 63.45

GC content: 46.07

Gene sequence:

>1413_bases
ATGACTGTCTCTACTCGTCAAGAAAGCGACCTTCTGGGCAATCGTGATATTCCCGCTGATGCTTATTATGGCATTCAAAC
CCTACGTGCCTTTGAAAACTTCCCCATTAGCGGTGTGCGCTTGCACCAATTTGCCCCATTTATCAGAGCCTTTGCTACCG
TAAAAAAAGCGGCAGCCATTACCAACCATAAAGTAGGCGTATTGGATGAGAAAATTAAAGATGCCATCTGCGCCGCTTGT
GATGACTTAATTGCGGACAAATACCACGATCAATTTATTATTGATATGTTCCAAGGCGGTGCTGGTACCTCAACCAACAT
GAACGTTAATGAGGTAATTGCCAACCGTGCGTTAGAGATTATGGGTCACAACAAAGGCGAGTATCAGTATTTACATCCGA
ATAACCACGTGAACCTGTCACAATCGACCAACGACTCCTACCCCACCGCCTTAAAGCTGGCACTAGATCACTACTGTGAA
CGCTTACTTGGTAAGATGGACATCCTGCTTGAGAGCTTCTTAAATAAAAAGCAAGCCTTAGGCGATCGCTTAAAGATGGG
ACGCACCCACTTACAAGATGCTGTGCCAATGACAGCTGGACAAGAGTTCAATGCCTTTGCCACCATGATTAAGGCTGAAA
AAAAGCGCATTGAGCAAGTGCGGGAGCTGTTGTATGAGATTAACATGGGTGCCACTGCCATCGGTACCGGCATTAATGCG
CCATCTAATTATCCTGAAACCTGTGCTGAGGTTCTAAGGCAGCTTACGGGCAAACCCTATTACACCTCAGATGACTTAGT
GCAAGCCACCCAAGATACCAGTGTCTATGTCGCGCTATCAGGTAACTTGCGCCTACTCGCTACCCGGTTATCAAAGATTG
CCAATGACATTCGCTTGCAATCTTCTGGACCGCGCGCCGGCCTAGGACAATACCGCATTCCGCAAATGCAGCCTGGTAGC
TCTATCATGCCTGGTAAGGTTAACCCTGTCATTCCAGAAGTGGTCAACCAAGCGTGTTTTCATGTGATGGGTATTGACCA
CACCATTGCTATGGCATCAGAGGCGGGACAATTGCAGTTGAACGTGTTTGAACCTGTGATGGCGTTCAACTTATTCACCG
GCCTATCTATGATGGGTAATATCTGTGAAACCTTTGCGACTCGCTGTATCGATGGTATTGAGATGAATGAAGATTATTGT
CGTCAGCAAGTGCTGAGCAATATTGGTCTGGTCACAGCGCTTAACCCGCATTTGGGCTATGAAGTTTCGACAAGAATTGC
CAAAAAGGCGCAAGAAAGTGGCGGCAGTGTGTACAACATAGTACTAGAAGAAAAACTGTTAGATCAGTCCACACTTGATG
AGATTATCTCACCTGAAAACATGGTGTATCCGCTGCTAAAAAATAAAGCTTAA

Upstream 100 bases:

>100_bases
CATGGTAATCAAAACCTTTTATTCAGCTTAATTATTTTTTTAACTGTGCTATGGTATAAGGCTTAACTTGTTTAAGACCT
CTTTTTAGGATGATATACGT

Downstream 100 bases:

>100_bases
ATCGATTCTGCAACAACAGGCACAAAAAGGCAGATTATCTATTGATAATCTGCCTTTTTTTAAGTAGCCTATTTTACTTT
AATAACCTTCAAGGACTTGG

Product: aspartate ammonia-lyase

Products: NA

Alternate protein names: Aspartase [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTVSTRQESDLLGNRDIPADAYYGIQTLRAFENFPISGVRLHQFAPFIRAFATVKKAAAITNHKVGVLDEKIKDAICAAC
DDLIADKYHDQFIIDMFQGGAGTSTNMNVNEVIANRALEIMGHNKGEYQYLHPNNHVNLSQSTNDSYPTALKLALDHYCE
RLLGKMDILLESFLNKKQALGDRLKMGRTHLQDAVPMTAGQEFNAFATMIKAEKKRIEQVRELLYEINMGATAIGTGINA
PSNYPETCAEVLRQLTGKPYYTSDDLVQATQDTSVYVALSGNLRLLATRLSKIANDIRLQSSGPRAGLGQYRIPQMQPGS
SIMPGKVNPVIPEVVNQACFHVMGIDHTIAMASEAGQLQLNVFEPVMAFNLFTGLSMMGNICETFATRCIDGIEMNEDYC
RQQVLSNIGLVTALNPHLGYEVSTRIAKKAQESGGSVYNIVLEEKLLDQSTLDEIISPENMVYPLLKNKA

Sequences:

>Translated_470_residues
MTVSTRQESDLLGNRDIPADAYYGIQTLRAFENFPISGVRLHQFAPFIRAFATVKKAAAITNHKVGVLDEKIKDAICAAC
DDLIADKYHDQFIIDMFQGGAGTSTNMNVNEVIANRALEIMGHNKGEYQYLHPNNHVNLSQSTNDSYPTALKLALDHYCE
RLLGKMDILLESFLNKKQALGDRLKMGRTHLQDAVPMTAGQEFNAFATMIKAEKKRIEQVRELLYEINMGATAIGTGINA
PSNYPETCAEVLRQLTGKPYYTSDDLVQATQDTSVYVALSGNLRLLATRLSKIANDIRLQSSGPRAGLGQYRIPQMQPGS
SIMPGKVNPVIPEVVNQACFHVMGIDHTIAMASEAGQLQLNVFEPVMAFNLFTGLSMMGNICETFATRCIDGIEMNEDYC
RQQVLSNIGLVTALNPHLGYEVSTRIAKKAQESGGSVYNIVLEEKLLDQSTLDEIISPENMVYPLLKNKA
>Mature_469_residues
TVSTRQESDLLGNRDIPADAYYGIQTLRAFENFPISGVRLHQFAPFIRAFATVKKAAAITNHKVGVLDEKIKDAICAACD
DLIADKYHDQFIIDMFQGGAGTSTNMNVNEVIANRALEIMGHNKGEYQYLHPNNHVNLSQSTNDSYPTALKLALDHYCER
LLGKMDILLESFLNKKQALGDRLKMGRTHLQDAVPMTAGQEFNAFATMIKAEKKRIEQVRELLYEINMGATAIGTGINAP
SNYPETCAEVLRQLTGKPYYTSDDLVQATQDTSVYVALSGNLRLLATRLSKIANDIRLQSSGPRAGLGQYRIPQMQPGSS
IMPGKVNPVIPEVVNQACFHVMGIDHTIAMASEAGQLQLNVFEPVMAFNLFTGLSMMGNICETFATRCIDGIEMNEDYCR
QQVLSNIGLVTALNPHLGYEVSTRIAKKAQESGGSVYNIVLEEKLLDQSTLDEIISPENMVYPLLKNKA

Specific function: Unknown

COG id: COG1027

COG function: function code E; Aspartate ammonia-lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily [H]

Homologues:

Organism=Homo sapiens, GI19743875, Length=462, Percent_Identity=40.2597402597403, Blast_Score=346, Evalue=3e-95,
Organism=Escherichia coli, GI87082375, Length=470, Percent_Identity=50.2127659574468, Blast_Score=460, Evalue=1e-130,
Organism=Escherichia coli, GI1787896, Length=460, Percent_Identity=39.3478260869565, Blast_Score=340, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17553882, Length=460, Percent_Identity=40, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI32565146, Length=327, Percent_Identity=37.0030581039755, Blast_Score=243, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6324993, Length=465, Percent_Identity=40, Blast_Score=356, Evalue=4e-99,
Organism=Drosophila melanogaster, GI24662684, Length=465, Percent_Identity=40, Blast_Score=353, Evalue=1e-97,
Organism=Drosophila melanogaster, GI24640179, Length=461, Percent_Identity=39.0455531453362, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24640177, Length=461, Percent_Identity=39.0455531453362, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24583245, Length=466, Percent_Identity=38.6266094420601, Blast_Score=338, Evalue=4e-93,
Organism=Drosophila melanogaster, GI78710009, Length=462, Percent_Identity=38.0952380952381, Blast_Score=337, Evalue=8e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004708
- InterPro:   IPR003031
- InterPro:   IPR018951
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761 [H]

Pfam domain/function: PF10415 FumaraseC_C; PF00206 Lyase_1 [H]

EC number: =4.3.1.1 [H]

Molecular weight: Translated: 51892; Mature: 51761

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSTRQESDLLGNRDIPADAYYGIQTLRAFENFPISGVRLHQFAPFIRAFATVKKAAAI
CCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
TNHKVGVLDEKIKDAICAACDDLIADKYHDQFIIDMFQGGAGTSTNMNVNEVIANRALEI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
MGHNKGEYQYLHPNNHVNLSQSTNDSYPTALKLALDHYCERLLGKMDILLESFLNKKQAL
HCCCCCCEEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDRLKMGRTHLQDAVPMTAGQEFNAFATMIKAEKKRIEQVRELLYEINMGATAIGTGINA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
PSNYPETCAEVLRQLTGKPYYTSDDLVQATQDTSVYVALSGNLRLLATRLSKIANDIRLQ
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHEEC
SSGPRAGLGQYRIPQMQPGSSIMPGKVNPVIPEVVNQACFHVMGIDHTIAMASEAGQLQL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEE
NVFEPVMAFNLFTGLSMMGNICETFATRCIDGIEMNEDYCRQQVLSNIGLVTALNPHLGY
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCC
EVSTRIAKKAQESGGSVYNIVLEEKLLDQSTLDEIISPENMVYPLLKNKA
HHHHHHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHCCCCHHEEHHHCCCC
>Mature Secondary Structure 
TVSTRQESDLLGNRDIPADAYYGIQTLRAFENFPISGVRLHQFAPFIRAFATVKKAAAI
CCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
TNHKVGVLDEKIKDAICAACDDLIADKYHDQFIIDMFQGGAGTSTNMNVNEVIANRALEI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
MGHNKGEYQYLHPNNHVNLSQSTNDSYPTALKLALDHYCERLLGKMDILLESFLNKKQAL
HCCCCCCEEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDRLKMGRTHLQDAVPMTAGQEFNAFATMIKAEKKRIEQVRELLYEINMGATAIGTGINA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
PSNYPETCAEVLRQLTGKPYYTSDDLVQATQDTSVYVALSGNLRLLATRLSKIANDIRLQ
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHEEC
SSGPRAGLGQYRIPQMQPGSSIMPGKVNPVIPEVVNQACFHVMGIDHTIAMASEAGQLQL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEE
NVFEPVMAFNLFTGLSMMGNICETFATRCIDGIEMNEDYCRQQVLSNIGLVTALNPHLGY
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCC
EVSTRIAKKAQESGGSVYNIVLEEKLLDQSTLDEIISPENMVYPLLKNKA
HHHHHHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHCCCCHHEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]