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The map label for this gene is arsB [H]

Identifier: 148652945

GI number: 148652945

Start: 1394235

End: 1395539

Strand: Direct

Name: arsB [H]

Synonym: PsycPRwf_1139

Alternate gene names: 148652945

Gene position: 1394235-1395539 (Clockwise)

Preceding gene: 148652942

Following gene: 148652946

Centisome position: 46.8

GC content: 48.89

Gene sequence:

>1305_bases
ATGGTACTTGCGGCGCTTATTTTTGTGGTTACATTGGTGCTGGTTATCTGGCAGCCCAAAGGGCTTGGTATCGGGGTAAG
CGCCAGCCTAGGCGCACTGGCGGCGTTATTAATGGGGGTAATCTCCTTAGCGGATATCCCTGTGGTCTGGGACATCGTGT
GGAATGCTACCTTTGCGTTTATTGCCATTATTATTATCAGTCTGCTTCTGGATCAAGCCGGGTTTTTTGAATGGATAGCG
CTGCATGTGGCACGACTGGGCGGGGGTAATGCCAAGCTATTATTTGTGCTTATTGTGCTACTTGGGGCTGTGGTATCGGC
GTTGTTTGCTAATGATGGCGCAGCGCTAATTTTGACCCCTATTGTGATAGCTATGCTGCTTAAGATGCGGGTGTCTGCCG
CCACTACCTTGGCTTTTATCATGGCAGCAGGTTTTATTGCGGATACGGCAAGCTTGCCGCTGGTGGTATCCAACCTGGTT
AATATCGTATCGGCAGATTTTTTTAACTTAAGCTTTGATCGTTATGCTCAGGTGATGCTGCCGGTGAATATGGTGTCGGT
ACTAAGCTCACTTGCGGTACTGTACTTTTTTTATCAAAAAGACATTCCCGCCACATATGAGGTGGCTAATTTACCAAGTC
CGCATAGTGTCATTAAGGATAAGGCGACCTTTGTTACTGGCTGGGTGGTATTGGCTGCCTTATTGGTGGGGTTCTTTGTA
CTAGAGCCTAGAGGCGTGCCCATTAGCCTAATCGCAGCCATAGGGGCGTTGGTGTTAATCTTGACGGCATTGGCCAATAA
AAAACTGTCAGTATCTAGTGTATTAAAAGGGGCACCTTGGCAAGTGGTGGTGTTCTCACTGGGCATGTATCTGGTGGTTT
ATGGCCTAAAAAACGAAGGGCTAACCGGTTATCTTACCCAAGCTCTAAATGCTCTGGGCGGGCAGGGGCTGTGGGCGGCC
ACAATTGGCACCGGCTTTATGTCGGCGGGTCTGTCCTCGATTATGAATAACATGCCCACTGTATTGATGCAGTCGCTGGC
CATTGCTGATGTAAATACATCGACCTTTAGTGAGCCTGAGCAGATACATCAAGCGATGGTCTATGCCAATGTGATTGGCT
CAGACTTAGGGCCAAAGATTACGCCCATCGGCTCACTGGCAACCTTGTTGTGGCTACATGTGCTGGCAAGTAAGGAGGTG
GTCATTACTTGGGGTTATTACTTTAAGGTGGGCGTTATCCTAACGGTGCCGGTACTGCTGGCAACTTTAATGGCACTGGC
GCTTTGGCTACCTATGATCAGTTAG

Upstream 100 bases:

>100_bases
ACTCCCTGATTGATAAATAGTAGCACAGGCTTATGCGATATTTTTGAATATATATAGTTTAAATATAGTTGTTTAATTCA
CTACACAATAGAGAGTGGTT

Downstream 100 bases:

>100_bases
TAGATGGCTAGTAGTTGGCTAGTAGCAAGTAAGTAGAGAATAGGTAGGGCGCAGCTAGTAAAGAATAGAATAGAGCGCAC
TAAACAAGCGCTGTAATATG

Product: arsenical pump membrane protein

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MVLAALIFVVTLVLVIWQPKGLGIGVSASLGALAALLMGVISLADIPVVWDIVWNATFAFIAIIIISLLLDQAGFFEWIA
LHVARLGGGNAKLLFVLIVLLGAVVSALFANDGAALILTPIVIAMLLKMRVSAATTLAFIMAAGFIADTASLPLVVSNLV
NIVSADFFNLSFDRYAQVMLPVNMVSVLSSLAVLYFFYQKDIPATYEVANLPSPHSVIKDKATFVTGWVVLAALLVGFFV
LEPRGVPISLIAAIGALVLILTALANKKLSVSSVLKGAPWQVVVFSLGMYLVVYGLKNEGLTGYLTQALNALGGQGLWAA
TIGTGFMSAGLSSIMNNMPTVLMQSLAIADVNTSTFSEPEQIHQAMVYANVIGSDLGPKITPIGSLATLLWLHVLASKEV
VITWGYYFKVGVILTVPVLLATLMALALWLPMIS

Sequences:

>Translated_434_residues
MVLAALIFVVTLVLVIWQPKGLGIGVSASLGALAALLMGVISLADIPVVWDIVWNATFAFIAIIIISLLLDQAGFFEWIA
LHVARLGGGNAKLLFVLIVLLGAVVSALFANDGAALILTPIVIAMLLKMRVSAATTLAFIMAAGFIADTASLPLVVSNLV
NIVSADFFNLSFDRYAQVMLPVNMVSVLSSLAVLYFFYQKDIPATYEVANLPSPHSVIKDKATFVTGWVVLAALLVGFFV
LEPRGVPISLIAAIGALVLILTALANKKLSVSSVLKGAPWQVVVFSLGMYLVVYGLKNEGLTGYLTQALNALGGQGLWAA
TIGTGFMSAGLSSIMNNMPTVLMQSLAIADVNTSTFSEPEQIHQAMVYANVIGSDLGPKITPIGSLATLLWLHVLASKEV
VITWGYYFKVGVILTVPVLLATLMALALWLPMIS
>Mature_434_residues
MVLAALIFVVTLVLVIWQPKGLGIGVSASLGALAALLMGVISLADIPVVWDIVWNATFAFIAIIIISLLLDQAGFFEWIA
LHVARLGGGNAKLLFVLIVLLGAVVSALFANDGAALILTPIVIAMLLKMRVSAATTLAFIMAAGFIADTASLPLVVSNLV
NIVSADFFNLSFDRYAQVMLPVNMVSVLSSLAVLYFFYQKDIPATYEVANLPSPHSVIKDKATFVTGWVVLAALLVGFFV
LEPRGVPISLIAAIGALVLILTALANKKLSVSSVLKGAPWQVVVFSLGMYLVVYGLKNEGLTGYLTQALNALGGQGLWAA
TIGTGFMSAGLSSIMNNMPTVLMQSLAIADVNTSTFSEPEQIHQAMVYANVIGSDLGPKITPIGSLATLLWLHVLASKEV
VITWGYYFKVGVILTVPVLLATLMALALWLPMIS

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=430, Percent_Identity=66.9767441860465, Blast_Score=534, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 45932; Mature: 45932

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]