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The map label for this gene is yiaY [H]

Identifier: 148652878

GI number: 148652878

Start: 1291263

End: 1292339

Strand: Direct

Name: yiaY [H]

Synonym: PsycPRwf_1071

Alternate gene names: 148652878

Gene position: 1291263-1292339 (Clockwise)

Preceding gene: 148652877

Following gene: 148652880

Centisome position: 43.35

GC content: 47.35

Gene sequence:

>1077_bases
TTGGCAAGATTTAATTGCAAAAAAGTATTTGTTGTAACCGATAAGATTCTGGAAGAAATTGGGGTCGTAAAGCAGATTAC
GGGGCCGCTAGAGTCAAAGGGCATCGAGATTAAGCTGTTCACCGAGGTTCAGCCCAACCCCACTGTGGCAAACGTCGAAG
CAGGTCTGACTGAGCTAAAAACATTCGAGGCAGACTTAATGATTTCTCTTGGTGGCGGATCAGTGCATGACTGCGCTAAA
GCGATAGCTGTCGTGGCTACCAATGGCGGCAAGATTCAAGACTATGAAGGATTAGATAAGTCTAGCAAGCCGACACTGCC
TTTGGTGGCCATCAACACCACCGCAGGTACCGCCTCTGAGATGACTCGATTCTGCATCATCACCGATGAGTCAACCCACA
TTAAGATGGCCATTGTTGACAGCAATTTAACGCCCATGCTGTCTATTAACGACTCAGGCATTATGTCTAACATGCCAGCA
GGATTGACTGCAGCAACCGGTATGGATGCGTTAACTCACGCTGTTGAGGCCTATGTATCTACCGCGGCCAGTCCCATTAC
GGATGCTTGCGCTCTAAAGGCCATTGAGCTAATCGCTCAGGCATTACCTACGGCAGTAGTTGAGCCTAAAAACATGCAGG
CTCGTGAAGACATGGCCTACGCTCAGTTCTTAGCAGGGATGGCATTTAACAACGCCTCTTTGGGCTACGTGCACGCTATG
GCGCACCAGTTAGGTGGTATGTATGACTTACCGCATGGGGTGTGTAATGCACTGCTATTGCCACATGTGGAAGCTTTTAA
CCAATCAGCGGCCAAAGACAGGCTGGATGTGATTGGTAAAGTATTGGGTGATAATAACGCCAATCTTGCTGGTCTAGATA
CCATTGATGCGATTAAAAAACTGGCAGATATTGTTAATATTCCTAAGTCTTTAAAAGAGCTTGGCGTAAAACGTGAAGAT
TTCGATGAGCTGGCCACTAATGCCTTAAAAGATGTGTGCGGCCTCACCAACCCGATTCAAGCCACTCATGAACAAATCGT
GGGTATCTTTGAAGATGCCTTTGAAGCGCGCTCATAG

Upstream 100 bases:

>100_bases
CCGTCTAGCTGTAGCAATCCCCTCGGTTTAGCGAGGGGAGGAAGTCAAGCCTTCTAATAACTTAATTGGGGAAGGCGCAT
TAGAAAAAGGTCTTGAGCAG

Downstream 100 bases:

>100_bases
TCTACTTCAGCCCGCTCTTATCAACGTAGCAAATCAGTTATAGGGGGCATATAAAAAGGCAGATTAGACCTAATGGATTA
AGTCTCTTCTGCCTTTTATC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MARFNCKKVFVVTDKILEEIGVVKQITGPLESKGIEIKLFTEVQPNPTVANVEAGLTELKTFEADLMISLGGGSVHDCAK
AIAVVATNGGKIQDYEGLDKSSKPTLPLVAINTTAGTASEMTRFCIITDESTHIKMAIVDSNLTPMLSINDSGIMSNMPA
GLTAATGMDALTHAVEAYVSTAASPITDACALKAIELIAQALPTAVVEPKNMQAREDMAYAQFLAGMAFNNASLGYVHAM
AHQLGGMYDLPHGVCNALLLPHVEAFNQSAAKDRLDVIGKVLGDNNANLAGLDTIDAIKKLADIVNIPKSLKELGVKRED
FDELATNALKDVCGLTNPIQATHEQIVGIFEDAFEARS

Sequences:

>Translated_358_residues
MARFNCKKVFVVTDKILEEIGVVKQITGPLESKGIEIKLFTEVQPNPTVANVEAGLTELKTFEADLMISLGGGSVHDCAK
AIAVVATNGGKIQDYEGLDKSSKPTLPLVAINTTAGTASEMTRFCIITDESTHIKMAIVDSNLTPMLSINDSGIMSNMPA
GLTAATGMDALTHAVEAYVSTAASPITDACALKAIELIAQALPTAVVEPKNMQAREDMAYAQFLAGMAFNNASLGYVHAM
AHQLGGMYDLPHGVCNALLLPHVEAFNQSAAKDRLDVIGKVLGDNNANLAGLDTIDAIKKLADIVNIPKSLKELGVKRED
FDELATNALKDVCGLTNPIQATHEQIVGIFEDAFEARS
>Mature_357_residues
ARFNCKKVFVVTDKILEEIGVVKQITGPLESKGIEIKLFTEVQPNPTVANVEAGLTELKTFEADLMISLGGGSVHDCAKA
IAVVATNGGKIQDYEGLDKSSKPTLPLVAINTTAGTASEMTRFCIITDESTHIKMAIVDSNLTPMLSINDSGIMSNMPAG
LTAATGMDALTHAVEAYVSTAASPITDACALKAIELIAQALPTAVVEPKNMQAREDMAYAQFLAGMAFNNASLGYVHAMA
HQLGGMYDLPHGVCNALLLPHVEAFNQSAAKDRLDVIGKVLGDNNANLAGLDTIDAIKKLADIVNIPKSLKELGVKREDF
DELATNALKDVCGLTNPIQATHEQIVGIFEDAFEARS

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=388, Percent_Identity=26.8041237113402, Blast_Score=108, Evalue=9e-24,
Organism=Escherichia coli, GI48994951, Length=358, Percent_Identity=61.731843575419, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789163, Length=361, Percent_Identity=40.9972299168975, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI87082107, Length=347, Percent_Identity=38.6167146974063, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787493, Length=396, Percent_Identity=34.5959595959596, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789386, Length=252, Percent_Identity=26.1904761904762, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17537053, Length=392, Percent_Identity=25.765306122449, Blast_Score=118, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6321181, Length=351, Percent_Identity=55.5555555555556, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24657991, Length=396, Percent_Identity=27.020202020202, Blast_Score=111, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 37955; Mature: 37824

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFNCKKVFVVTDKILEEIGVVKQITGPLESKGIEIKLFTEVQPNPTVANVEAGLTELK
CCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCEEEEEEEECCCCCCEEEHHHHHHHHH
TFEADLMISLGGGSVHDCAKAIAVVATNGGKIQDYEGLDKSSKPTLPLVAINTTAGTASE
HHCEEEEEEECCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHH
MTRFCIITDESTHIKMAIVDSNLTPMLSINDSGIMSNMPAGLTAATGMDALTHAVEAYVS
CEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TAASPITDACALKAIELIAQALPTAVVEPKNMQAREDMAYAQFLAGMAFNNASLGYVHAM
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHQLGGMYDLPHGVCNALLLPHVEAFNQSAAKDRLDVIGKVLGDNNANLAGLDTIDAIKK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LADIVNIPKSLKELGVKREDFDELATNALKDVCGLTNPIQATHEQIVGIFEDAFEARS
HHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARFNCKKVFVVTDKILEEIGVVKQITGPLESKGIEIKLFTEVQPNPTVANVEAGLTELK
CCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCEEEEEEEECCCCCCEEEHHHHHHHHH
TFEADLMISLGGGSVHDCAKAIAVVATNGGKIQDYEGLDKSSKPTLPLVAINTTAGTASE
HHCEEEEEEECCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHH
MTRFCIITDESTHIKMAIVDSNLTPMLSINDSGIMSNMPAGLTAATGMDALTHAVEAYVS
CEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TAASPITDACALKAIELIAQALPTAVVEPKNMQAREDMAYAQFLAGMAFNNASLGYVHAM
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHQLGGMYDLPHGVCNALLLPHVEAFNQSAAKDRLDVIGKVLGDNNANLAGLDTIDAIKK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LADIVNIPKSLKELGVKREDFDELATNALKDVCGLTNPIQATHEQIVGIFEDAFEARS
HHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]