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The map label for this gene is nhaC [H]

Identifier: 148652850

GI number: 148652850

Start: 1249751

End: 1251163

Strand: Direct

Name: nhaC [H]

Synonym: PsycPRwf_1043

Alternate gene names: 148652850

Gene position: 1249751-1251163 (Clockwise)

Preceding gene: 148652849

Following gene: 148652856

Centisome position: 41.95

GC content: 46.21

Gene sequence:

>1413_bases
ATGCCTCCACAAATACTTACTCAAATCTCCCCCAAACTTGCCTTCGTGCTCTCAACCATCATCATTGCCATCATGGGCGT
GACCATGATTGGCTTTGGCTGGGTGCCACATTTGTCTTTGATACTTGCCATCTGTGTGTTGTTGGCAATAGGCCTGATTA
AAGGGCTGAGTTTTGATGAGATGCAGTCACAAATGGCGGTAGGCGTGCTGCGCGGTATTGGCGCTATTTATTTGTTTTTC
TTTATTGGTCTGATGGTATCGGCTTTAATGATGTCAGGGGCGATACCTACCTTAATGTACTTTGGTTTTGAGCTGATTTC
TCCGCAGTTTTATTATATTTCAGCCTTTGTGCTGACCTCCATTATTGGCGTGGCCTTGGGCAGTAGCTTAACCACAGTAG
CCACGCTGGGGGTAGCGTTTATTGGTATGAGTCATGCCTTTGATGCGAACGTGGCAATCGCCGCTGGTGCTGTGGTATCA
GGTGCGTTTTTTGGCGATAAAATGTCGCCCTTATCCGATACCTGTACTATTGCCTCATCCATTGTGGGCATAGATTTGTT
TGAACATATTCGCAATATGACGTACACCACAGTGCCAGCTTGGATACTCACCTTTGGACTATTTTGGCTGTTATCAGGAG
ACACCACCACGTCAGACTTAAGTCAGGTACGAGCGCTTCAAACACAGTTGGTAGACAGCGGCTTGGTCCATGGCTATTCG
GTATTGCCCTTTGTGGTACTGGTGGTGATGGCGTTGTGCCGTATCAATGCCATTTATACCATTATCTGCACCATCGTTGT
CGCACTAATCATAACCTATGTGCACAGCTCACCGAGCTTGGCAGATTTGGGAGGGTATTTCTTTAGTGGCTATCATCCAG
CAGAATCTTTAGATCTTGGTGAAGTGGGCGGCATGTTATCGCGTGGCGGGGTAAACAGCATGTTCTTTACTCAGACTATT
GTGATTTTAGCATTAAGCTTAGGGGGTTTATTAACTGCACTGGGTATCTTGCCTGCCTTATTAACGGGCATTAAAGACAG
CTTGACCACCTCAGGCCGAGCCATTGCAGCAGCAGCGATGTCTGCCTTGAGTATCAACGTACTTATCGGTGAGCAGTATT
TAAGCTTACTGTTGTCAGGCACAGCGTTTCGACCTGTGTTTGAAAGATTAAATTTACACCCAAAAAACCTATCACGTACC
ATTGAAGATGCCGGTACAGTGATTAATCCTTTGGTGCCTTGGAGTGTGTGCGGGGTGTTTATTAGCCAAGCTTTAGGCGT
CTCTGTCATTGAGTATTTGCCCTATGCCTTCTTCTGTTATTTGTCTTTTTTCTTGACCATCATCTTTGGCTTTAGCGGCA
TTACCATCACCAAAACCAATACAACTGCCCAGCCGGTGGTAACCCCAAGCTAA

Upstream 100 bases:

>100_bases
CCGATGTGCTGTATCAGCCTTAACTGGGTCGTCTTTTACTGAGTCAATTTAAAATCAACAATGAAATTTATCACCTTCAT
GGCAACATAAGGATATGTTA

Downstream 100 bases:

>100_bases
AGCTTAGCAAGGCGGCCTAAAAAAGGGCTTAGCGCTTAAGTTATTTAAGTGCTAAGCCCTTTTTGCTGTGCTTATAATGT
GCTGTGTCTAAATGCAAGCT

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MPPQILTQISPKLAFVLSTIIIAIMGVTMIGFGWVPHLSLILAICVLLAIGLIKGLSFDEMQSQMAVGVLRGIGAIYLFF
FIGLMVSALMMSGAIPTLMYFGFELISPQFYYISAFVLTSIIGVALGSSLTTVATLGVAFIGMSHAFDANVAIAAGAVVS
GAFFGDKMSPLSDTCTIASSIVGIDLFEHIRNMTYTTVPAWILTFGLFWLLSGDTTTSDLSQVRALQTQLVDSGLVHGYS
VLPFVVLVVMALCRINAIYTIICTIVVALIITYVHSSPSLADLGGYFFSGYHPAESLDLGEVGGMLSRGGVNSMFFTQTI
VILALSLGGLLTALGILPALLTGIKDSLTTSGRAIAAAAMSALSINVLIGEQYLSLLLSGTAFRPVFERLNLHPKNLSRT
IEDAGTVINPLVPWSVCGVFISQALGVSVIEYLPYAFFCYLSFFLTIIFGFSGITITKTNTTAQPVVTPS

Sequences:

>Translated_470_residues
MPPQILTQISPKLAFVLSTIIIAIMGVTMIGFGWVPHLSLILAICVLLAIGLIKGLSFDEMQSQMAVGVLRGIGAIYLFF
FIGLMVSALMMSGAIPTLMYFGFELISPQFYYISAFVLTSIIGVALGSSLTTVATLGVAFIGMSHAFDANVAIAAGAVVS
GAFFGDKMSPLSDTCTIASSIVGIDLFEHIRNMTYTTVPAWILTFGLFWLLSGDTTTSDLSQVRALQTQLVDSGLVHGYS
VLPFVVLVVMALCRINAIYTIICTIVVALIITYVHSSPSLADLGGYFFSGYHPAESLDLGEVGGMLSRGGVNSMFFTQTI
VILALSLGGLLTALGILPALLTGIKDSLTTSGRAIAAAAMSALSINVLIGEQYLSLLLSGTAFRPVFERLNLHPKNLSRT
IEDAGTVINPLVPWSVCGVFISQALGVSVIEYLPYAFFCYLSFFLTIIFGFSGITITKTNTTAQPVVTPS
>Mature_469_residues
PPQILTQISPKLAFVLSTIIIAIMGVTMIGFGWVPHLSLILAICVLLAIGLIKGLSFDEMQSQMAVGVLRGIGAIYLFFF
IGLMVSALMMSGAIPTLMYFGFELISPQFYYISAFVLTSIIGVALGSSLTTVATLGVAFIGMSHAFDANVAIAAGAVVSG
AFFGDKMSPLSDTCTIASSIVGIDLFEHIRNMTYTTVPAWILTFGLFWLLSGDTTTSDLSQVRALQTQLVDSGLVHGYSV
LPFVVLVVMALCRINAIYTIICTIVVALIITYVHSSPSLADLGGYFFSGYHPAESLDLGEVGGMLSRGGVNSMFFTQTIV
ILALSLGGLLTALGILPALLTGIKDSLTTSGRAIAAAAMSALSINVLIGEQYLSLLLSGTAFRPVFERLNLHPKNLSRTI
EDAGTVINPLVPWSVCGVFISQALGVSVIEYLPYAFFCYLSFFLTIIFGFSGITITKTNTTAQPVVTPS

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 49882; Mature: 49751

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
PPQILTQISPKLAFVLSTIIIAIMGVTMIGFGWVPHLSLILAICVLLAIGLIKGLSFDE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]