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The map label for this gene is pyrF [H]

Identifier: 148652751

GI number: 148652751

Start: 1128491

End: 1129234

Strand: Direct

Name: pyrF [H]

Synonym: PsycPRwf_0944

Alternate gene names: 148652751

Gene position: 1128491-1129234 (Clockwise)

Preceding gene: 148652750

Following gene: 148652752

Centisome position: 37.88

GC content: 48.66

Gene sequence:

>744_bases
GTGACCCAACTTCAGCAGTCCAAGTCAATTCTGCAAAACAAACCACAATTAACCCGGCCCAATTCGCCTATTATTGTGGC
GTTAGATAAAGCCTCTTTGAATGAAGCCTTGGCTTTGGCCGATCAGCTGGATCCTAAGTATTGCCGCGTAAAAGTGGGTA
AAGAGCTGTTTACACGCTGTGGACCTCAAATTATCGATGAGTTACATCAACGAGGCTTTGAGGTGTTTTTGGATCTAAAA
TTCCATGACATTCCCAATACCACAGCACAAGCGGTATTGGCAGCAGCAGATATGGGGGTATGGATGGTCAATGTACATGC
CAGTGCTGGTCTTGAAGCGATGCAGACGGCCAAAGAGCGCTTGGTAAACGGTGGCCATGAGACGTTATTGATTGCAGTGA
CAGTATTGACCTCTATGACTGAGGTGGGGCTGCGTCAGCTGGGGATCGATGTGCCGGTCAATGAGCAAGTTGAGCGTTTG
GCGCTGCTGACTAAAGAGGCGGGACTTGATGGGGTAGTGTGCTCCGCTCAAGAGGCCAGTCGTCTCAAACAGCTTTGTGG
GATGGATTTTCAATTGGTGACCCCAGGCATCCGTACCCTTGAGGATGCAGCCGATGACCAAAAACGTATTTGTACCCCAG
AGCAGGCTATGAAAAACGGCTCAGATTATCTGGTTATAGGCCGCTCTATCACCCACGCTGATAATCCCACCCAAAAGATG
TCACAAATTCTTGATACGTTATGA

Upstream 100 bases:

>100_bases
TGCAGGCGCATCCTATATACTATTTATTTGCTCAAGCTTATCTGCTAAAGCGATTTAATCAGCTCATTTTATTATTTATG
ATACATGCTTAGGAGGCAAT

Downstream 100 bases:

>100_bases
AACTACAACTATTAAGTGATCTTCATATCGACAGTTATGCCAAACGCGATAAGCCGCTGGGCCATATCCCAAAGACAGCG
GCCGATATTATCTTGGTAGC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTQLQQSKSILQNKPQLTRPNSPIIVALDKASLNEALALADQLDPKYCRVKVGKELFTRCGPQIIDELHQRGFEVFLDLK
FHDIPNTTAQAVLAAADMGVWMVNVHASAGLEAMQTAKERLVNGGHETLLIAVTVLTSMTEVGLRQLGIDVPVNEQVERL
ALLTKEAGLDGVVCSAQEASRLKQLCGMDFQLVTPGIRTLEDAADDQKRICTPEQAMKNGSDYLVIGRSITHADNPTQKM
SQILDTL

Sequences:

>Translated_247_residues
MTQLQQSKSILQNKPQLTRPNSPIIVALDKASLNEALALADQLDPKYCRVKVGKELFTRCGPQIIDELHQRGFEVFLDLK
FHDIPNTTAQAVLAAADMGVWMVNVHASAGLEAMQTAKERLVNGGHETLLIAVTVLTSMTEVGLRQLGIDVPVNEQVERL
ALLTKEAGLDGVVCSAQEASRLKQLCGMDFQLVTPGIRTLEDAADDQKRICTPEQAMKNGSDYLVIGRSITHADNPTQKM
SQILDTL
>Mature_246_residues
TQLQQSKSILQNKPQLTRPNSPIIVALDKASLNEALALADQLDPKYCRVKVGKELFTRCGPQIIDELHQRGFEVFLDLKF
HDIPNTTAQAVLAAADMGVWMVNVHASAGLEAMQTAKERLVNGGHETLLIAVTVLTSMTEVGLRQLGIDVPVNEQVERLA
LLTKEAGLDGVVCSAQEASRLKQLCGMDFQLVTPGIRTLEDAADDQKRICTPEQAMKNGSDYLVIGRSITHADNPTQKMS
QILDTL

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=224, Percent_Identity=58.9285714285714, Blast_Score=256, Evalue=8e-70,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 27014; Mature: 26882

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLQQSKSILQNKPQLTRPNSPIIVALDKASLNEALALADQLDPKYCRVKVGKELFTRC
CCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GPQIIDELHQRGFEVFLDLKFHDIPNTTAQAVLAAADMGVWMVNVHASAGLEAMQTAKER
CHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHH
LVNGGHETLLIAVTVLTSMTEVGLRQLGIDVPVNEQVERLALLTKEAGLDGVVCSAQEAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECHHHHH
RLKQLCGMDFQLVTPGIRTLEDAADDQKRICTPEQAMKNGSDYLVIGRSITHADNPTQKM
HHHHHHCCCEEEECCCHHHHHHHCCCHHHCCCHHHHHHCCCCEEEECCCCCCCCCHHHHH
SQILDTL
HHHHHCC
>Mature Secondary Structure 
TQLQQSKSILQNKPQLTRPNSPIIVALDKASLNEALALADQLDPKYCRVKVGKELFTRC
CCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GPQIIDELHQRGFEVFLDLKFHDIPNTTAQAVLAAADMGVWMVNVHASAGLEAMQTAKER
CHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHH
LVNGGHETLLIAVTVLTSMTEVGLRQLGIDVPVNEQVERLALLTKEAGLDGVVCSAQEAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECHHHHH
RLKQLCGMDFQLVTPGIRTLEDAADDQKRICTPEQAMKNGSDYLVIGRSITHADNPTQKM
HHHHHHCCCEEEECCCHHHHHHHCCCHHHCCCHHHHHHCCCCEEEECCCCCCCCCHHHHH
SQILDTL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA