Click here to switch to the map view.

The map label for this gene is glnS [H]

Identifier: 148652623

GI number: 148652623

Start: 966658

End: 968451

Strand: Direct

Name: glnS [H]

Synonym: PsycPRwf_0814

Alternate gene names: 148652623

Gene position: 966658-968451 (Clockwise)

Preceding gene: 148652620

Following gene: 148652625

Centisome position: 32.45

GC content: 46.27

Gene sequence:

>1794_bases
ATGAATGATACCCCCAAGTTTTATAATAGGAGAAGTAATTCGATGAGCACTGAAAATAATAAAGCGAATGCCTCAGCTGA
GCACAAAGAGGATCAAAAAAACGATTTTATTCGTCATATCATTCGTGAAGATTTGGCCCAAGATAAATACAATCAAATCG
TGACCCGATTTCCGCCTGAGCCAAATGGCTACTTGCATTTGGGTCATGTCAAATCTATCTGTCTAAACTTTGGAATTGCC
AAAGAGTTTGGCGGTATTTGTAATCTGCGCTTTGACGATACCAACCCCACTGCCGAGAAGCAGGATTATATTGATAACAT
CAAAAACGACGTACAGTGGTTGGGCTTTGAGTGGGCCGATCAGCCTTATTATGCGTCAGGCTACTTCGATCAGCTACATG
AATGGGCCATTAAACTGATCAAGCAAGGCGATGCCTATGTTGACTTGCAAACACCGGAGCAAATTAAAGAAAACCGTGGT
TCATTTAATGAGCCAGGTAAGCCGTCGCCACAGCGTGATACCAGCGTAGAAGAAAACTTGCAGCGCTTTGATGATATGAA
AAATGGTAAATATGCCGAGGGTGAGGCAGTACTGCGTGCCAAGATTGATATGGCAAGCCCCAATATGAATATGCGTGACC
CTGTTATTTATCGCGTTATGCATCAAGCACATCACCAAACGGGTGATAAATGGTGCATCTATCCGATGTATGATTATGCG
CATCCCTTATCGGACGCCATTGAAGGGATTACACACTCCTTATGTACGCTAGAGTTTGAAGATCATCGTCCGTTTTATGA
TTGGGCTGTAGAGAAGATTGGCTTTGATGTACCACCACATCAGTATGAGTTTAGCCGTCTAAATGTTGATCACACCATGA
CCAGTAAGCGTAAGCTTAAGCAGTTGGTTGATGAGCACATTGTCAGCGGCTGGGATGATCCACGTATGCCGACCATTGCT
GGCATGCGTCGCCGTGGCTATACGCCAGAAGGCTTACGTGATTTTTGTGACCGTGTTGGTGTGACCAAAGCCGATAGCGT
GGTAGATTTCCGTTTGCTTGAATTTAGCATTCGTCAATCGCTTGAGAACACCACCGCGCGTGGTATGGCGGTATTAAAAC
CTCTAAAAGTGACCATCACTAACTTTGATGAGGCGTTAAGTGAGTGGGAAAGCCTAAAAGATGACGGCGTTAATGCGCGC
TGGGATGAGGCGAGCAAGACCTTATGGATCAATCAGCCCAAGCACCCAAATATTGATATGGGCGAGCGTGAGATTCCTTT
TACTGAAACCATCTATATCGATCAAGGTGATTATGAGCTTGAGCCGCCAAAAGGTTATAAGCGTCTGTCTCCTGAGAAGC
CAGAGATTCGTCTGCGCAATACCTATGTATTGGCCGTGACGGAGCATGTGCTAGATGATGCAGGCAATGTGGTAGAGCTA
AAAGCCACTATCGATAAGACGACGCTGGGTAAAAACCCAGAAGACCGCAAAGTAAAAGGTGTGATTCACTGGGTATCAGC
CACGCAAGGCGTACCCGCAACCGTGCGTTTGTATGAGCATCTGTTTGCAGCAGAGAACCCAAGTGCGGTAGAGGACGTAC
ATCAAGCACTTAATGATCAGTCTTTAGTTGAGCTAGAGGCAGTCGTTGAGCCCGCTTTGGCCAATGCTGAGCCGGGCACT
CGCTTCCAGTTTGAGCGTGAAGGCTATTTTGTGGCGGATGAGGTAGAGCACAGCAGTGATAAGCCTGTGTTCAACCGCAC
TGTGACGTTACGCGATAGCTTTAAGCCAGAATAA

Upstream 100 bases:

>100_bases
TGCTCTTAAATTTAAAGGGGTAGTCTAACCTCTTTTTTTTGGGTTGTCATGTGTCTAGCTGTTACAGGGTTTGGTAAACC
TGATAGAATGGGGCAAAATT

Downstream 100 bases:

>100_bases
AATAAATAGCCTGGTAATCTTTGATAGACTAAAAGGCGCTAACGACATCTCGTTAGCGCCTTTTTTGGGGTGGTAGCAGT
AACATAAACGCCAGCACTTT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MNDTPKFYNRRSNSMSTENNKANASAEHKEDQKNDFIRHIIREDLAQDKYNQIVTRFPPEPNGYLHLGHVKSICLNFGIA
KEFGGICNLRFDDTNPTAEKQDYIDNIKNDVQWLGFEWADQPYYASGYFDQLHEWAIKLIKQGDAYVDLQTPEQIKENRG
SFNEPGKPSPQRDTSVEENLQRFDDMKNGKYAEGEAVLRAKIDMASPNMNMRDPVIYRVMHQAHHQTGDKWCIYPMYDYA
HPLSDAIEGITHSLCTLEFEDHRPFYDWAVEKIGFDVPPHQYEFSRLNVDHTMTSKRKLKQLVDEHIVSGWDDPRMPTIA
GMRRRGYTPEGLRDFCDRVGVTKADSVVDFRLLEFSIRQSLENTTARGMAVLKPLKVTITNFDEALSEWESLKDDGVNAR
WDEASKTLWINQPKHPNIDMGEREIPFTETIYIDQGDYELEPPKGYKRLSPEKPEIRLRNTYVLAVTEHVLDDAGNVVEL
KATIDKTTLGKNPEDRKVKGVIHWVSATQGVPATVRLYEHLFAAENPSAVEDVHQALNDQSLVELEAVVEPALANAEPGT
RFQFEREGYFVADEVEHSSDKPVFNRTVTLRDSFKPE

Sequences:

>Translated_597_residues
MNDTPKFYNRRSNSMSTENNKANASAEHKEDQKNDFIRHIIREDLAQDKYNQIVTRFPPEPNGYLHLGHVKSICLNFGIA
KEFGGICNLRFDDTNPTAEKQDYIDNIKNDVQWLGFEWADQPYYASGYFDQLHEWAIKLIKQGDAYVDLQTPEQIKENRG
SFNEPGKPSPQRDTSVEENLQRFDDMKNGKYAEGEAVLRAKIDMASPNMNMRDPVIYRVMHQAHHQTGDKWCIYPMYDYA
HPLSDAIEGITHSLCTLEFEDHRPFYDWAVEKIGFDVPPHQYEFSRLNVDHTMTSKRKLKQLVDEHIVSGWDDPRMPTIA
GMRRRGYTPEGLRDFCDRVGVTKADSVVDFRLLEFSIRQSLENTTARGMAVLKPLKVTITNFDEALSEWESLKDDGVNAR
WDEASKTLWINQPKHPNIDMGEREIPFTETIYIDQGDYELEPPKGYKRLSPEKPEIRLRNTYVLAVTEHVLDDAGNVVEL
KATIDKTTLGKNPEDRKVKGVIHWVSATQGVPATVRLYEHLFAAENPSAVEDVHQALNDQSLVELEAVVEPALANAEPGT
RFQFEREGYFVADEVEHSSDKPVFNRTVTLRDSFKPE
>Mature_597_residues
MNDTPKFYNRRSNSMSTENNKANASAEHKEDQKNDFIRHIIREDLAQDKYNQIVTRFPPEPNGYLHLGHVKSICLNFGIA
KEFGGICNLRFDDTNPTAEKQDYIDNIKNDVQWLGFEWADQPYYASGYFDQLHEWAIKLIKQGDAYVDLQTPEQIKENRG
SFNEPGKPSPQRDTSVEENLQRFDDMKNGKYAEGEAVLRAKIDMASPNMNMRDPVIYRVMHQAHHQTGDKWCIYPMYDYA
HPLSDAIEGITHSLCTLEFEDHRPFYDWAVEKIGFDVPPHQYEFSRLNVDHTMTSKRKLKQLVDEHIVSGWDDPRMPTIA
GMRRRGYTPEGLRDFCDRVGVTKADSVVDFRLLEFSIRQSLENTTARGMAVLKPLKVTITNFDEALSEWESLKDDGVNAR
WDEASKTLWINQPKHPNIDMGEREIPFTETIYIDQGDYELEPPKGYKRLSPEKPEIRLRNTYVLAVTEHVLDDAGNVVEL
KATIDKTTLGKNPEDRKVKGVIHWVSATQGVPATVRLYEHLFAAENPSAVEDVHQALNDQSLVELEAVVEPALANAEPGT
RFQFEREGYFVADEVEHSSDKPVFNRTVTLRDSFKPE

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=552, Percent_Identity=44.0217391304348, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI62241042, Length=568, Percent_Identity=32.9225352112676, Blast_Score=276, Evalue=5e-74,
Organism=Escherichia coli, GI1786895, Length=567, Percent_Identity=53.2627865961199, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI1788743, Length=308, Percent_Identity=23.3766233766234, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17543332, Length=552, Percent_Identity=39.8550724637681, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17511007, Length=537, Percent_Identity=31.6573556797021, Blast_Score=239, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6324742, Length=583, Percent_Identity=39.1080617495712, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321192, Length=574, Percent_Identity=33.6236933797909, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI17864488, Length=563, Percent_Identity=41.9182948490231, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24649466, Length=571, Percent_Identity=31.523642732049, Blast_Score=250, Evalue=2e-66,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 68660; Mature: 68660

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTPKFYNRRSNSMSTENNKANASAEHKEDQKNDFIRHIIREDLAQDKYNQIVTRFPPE
CCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PNGYLHLGHVKSICLNFGIAKEFGGICNLRFDDTNPTAEKQDYIDNIKNDVQWLGFEWAD
CCCEEEEHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECC
QPYYASGYFDQLHEWAIKLIKQGDAYVDLQTPEQIKENRGSFNEPGKPSPQRDTSVEENL
CCEECCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
QRFDDMKNGKYAEGEAVLRAKIDMASPNMNMRDPVIYRVMHQAHHQTGDKWCIYPMYDYA
HHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHH
HPLSDAIEGITHSLCTLEFEDHRPFYDWAVEKIGFDVPPHQYEFSRLNVDHTMTSKRKLK
CHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHEECCCHHHHHHHHHH
QLVDEHIVSGWDDPRMPTIAGMRRRGYTPEGLRDFCDRVGVTKADSVVDFRLLEFSIRQS
HHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LENTTARGMAVLKPLKVTITNFDEALSEWESLKDDGVNARWDEASKTLWINQPKHPNIDM
HHHHHHCCHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
GEREIPFTETIYIDQGDYELEPPKGYKRLSPEKPEIRLRNTYVLAVTEHVLDDAGNVVEL
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECEEEEEEEHHHHHCCCCEEEE
KATIDKTTLGKNPEDRKVKGVIHWVSATQGVPATVRLYEHLFAAENPSAVEDVHQALNDQ
EEECCHHHCCCCCCCCHHHHEEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SLVELEAVVEPALANAEPGTRFQFEREGYFVADEVEHSSDKPVFNRTVTLRDSFKPE
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MNDTPKFYNRRSNSMSTENNKANASAEHKEDQKNDFIRHIIREDLAQDKYNQIVTRFPPE
CCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PNGYLHLGHVKSICLNFGIAKEFGGICNLRFDDTNPTAEKQDYIDNIKNDVQWLGFEWAD
CCCEEEEHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECC
QPYYASGYFDQLHEWAIKLIKQGDAYVDLQTPEQIKENRGSFNEPGKPSPQRDTSVEENL
CCEECCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
QRFDDMKNGKYAEGEAVLRAKIDMASPNMNMRDPVIYRVMHQAHHQTGDKWCIYPMYDYA
HHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHH
HPLSDAIEGITHSLCTLEFEDHRPFYDWAVEKIGFDVPPHQYEFSRLNVDHTMTSKRKLK
CHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHEECCCHHHHHHHHHH
QLVDEHIVSGWDDPRMPTIAGMRRRGYTPEGLRDFCDRVGVTKADSVVDFRLLEFSIRQS
HHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LENTTARGMAVLKPLKVTITNFDEALSEWESLKDDGVNARWDEASKTLWINQPKHPNIDM
HHHHHHCCHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
GEREIPFTETIYIDQGDYELEPPKGYKRLSPEKPEIRLRNTYVLAVTEHVLDDAGNVVEL
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECEEEEEEEHHHHHCCCCEEEE
KATIDKTTLGKNPEDRKVKGVIHWVSATQGVPATVRLYEHLFAAENPSAVEDVHQALNDQ
EEECCHHHCCCCCCCCHHHHEEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SLVELEAVVEPALANAEPGTRFQFEREGYFVADEVEHSSDKPVFNRTVTLRDSFKPE
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]