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The map label for this gene is adk [H]

Identifier: 148652615

GI number: 148652615

Start: 960203

End: 960859

Strand: Direct

Name: adk [H]

Synonym: PsycPRwf_0806

Alternate gene names: 148652615

Gene position: 960203-960859 (Clockwise)

Preceding gene: 148652614

Following gene: 148652620

Centisome position: 32.23

GC content: 43.68

Gene sequence:

>657_bases
ATGATGCGTATTATTTTGCTAGGGCCTCCAGGGGCAGGTAAAGGCACCCAAGCACAATTCATATCTAAACAATATGATAT
TCCACAGATTTCTACCGGTGATATGCTACGTGCTGCCATCAAAGAGGGCACTGAGCTTGGCAAAAAAGCAGAAGGTATTA
TGAAATCTGGTGGCTTAGTATCAGACGACTTAATCATTAATTTGGTGAAAGAACGTATCGCTAAGCCTGACTGCGCTAAT
GGTTGTATCTTCGATGGCTTTCCACGCACTATTCCACAGGCTGAAGCGTTGATTGAAGCGGGTGTGGACATCGATCATGT
GGTAGAAATCAGCGTACCTGATGATGAGATCGTCTCTCGTTTATCAGGCCGTCGTCAGCACCCAGGCTCAGGCCGTGTGT
ATCACCTAAAATACAATCCGCCTAAGCAAGAAGGCTTAGATGATGAGACAGGTGAGCCACTTATCCAGCGTGATGACGAT
AAAGAAGAAACCATCCGTGATCGCTTAGCTACTTATCATGAGCAAACCTCTACTTTGGTTGGTTTTTACCAAAACAAAGC
CAAAGAAGATGCCAATGCCCCTAAATATCATCAATTCGATGGTACCAAAGATATTGAAGTGGTTAAAGAAAATATTCTTA
GTGCTCTAAAAGGCTAG

Upstream 100 bases:

>100_bases
AGTATATTTAGGGCTTGTGGTTATCGATGCTCAATTAATTTAGGCGCTTTATTTTTTGGATGATATTTGCTCATCTACAC
AACTTAAGAGGATTACGACT

Downstream 100 bases:

>100_bases
TCTTCAACATTATTTTAAGCATTAACGTAAAAAAACCTCAGTTCATCTTTGAACTGAGGTTTTTTTATATCACAATAAGC
TAATTAAGCGTTGCCTTCAC

Product: nucleoside-triphosphate--adenylate kinase

Products: NA

Alternate protein names: AK; ATP-AMP transphosphorylase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MMRIILLGPPGAGKGTQAQFISKQYDIPQISTGDMLRAAIKEGTELGKKAEGIMKSGGLVSDDLIINLVKERIAKPDCAN
GCIFDGFPRTIPQAEALIEAGVDIDHVVEISVPDDEIVSRLSGRRQHPGSGRVYHLKYNPPKQEGLDDETGEPLIQRDDD
KEETIRDRLATYHEQTSTLVGFYQNKAKEDANAPKYHQFDGTKDIEVVKENILSALKG

Sequences:

>Translated_218_residues
MMRIILLGPPGAGKGTQAQFISKQYDIPQISTGDMLRAAIKEGTELGKKAEGIMKSGGLVSDDLIINLVKERIAKPDCAN
GCIFDGFPRTIPQAEALIEAGVDIDHVVEISVPDDEIVSRLSGRRQHPGSGRVYHLKYNPPKQEGLDDETGEPLIQRDDD
KEETIRDRLATYHEQTSTLVGFYQNKAKEDANAPKYHQFDGTKDIEVVKENILSALKG
>Mature_218_residues
MMRIILLGPPGAGKGTQAQFISKQYDIPQISTGDMLRAAIKEGTELGKKAEGIMKSGGLVSDDLIINLVKERIAKPDCAN
GCIFDGFPRTIPQAEALIEAGVDIDHVVEISVPDDEIVSRLSGRRQHPGSGRVYHLKYNPPKQEGLDDETGEPLIQRDDD
KEETIRDRLATYHEQTSTLVGFYQNKAKEDANAPKYHQFDGTKDIEVVKENILSALKG

Specific function: This small ubiquitous enzyme is essential for maintenance and cell growth [H]

COG id: COG0563

COG function: function code F; Adenylate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenylate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4502013, Length=219, Percent_Identity=43.8356164383562, Blast_Score=196, Evalue=1e-50,
Organism=Homo sapiens, GI7524346, Length=219, Percent_Identity=43.8356164383562, Blast_Score=196, Evalue=1e-50,
Organism=Homo sapiens, GI19923437, Length=186, Percent_Identity=43.5483870967742, Blast_Score=168, Evalue=4e-42,
Organism=Homo sapiens, GI310110345, Length=203, Percent_Identity=38.423645320197, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI53832003, Length=203, Percent_Identity=38.423645320197, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI8051579, Length=203, Percent_Identity=38.423645320197, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI53832001, Length=203, Percent_Identity=38.423645320197, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI22749187, Length=199, Percent_Identity=28.643216080402, Blast_Score=104, Evalue=5e-23,
Organism=Homo sapiens, GI4502011, Length=185, Percent_Identity=29.7297297297297, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI237858799, Length=139, Percent_Identity=28.7769784172662, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI21450759, Length=139, Percent_Identity=28.7769784172662, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI28144897, Length=186, Percent_Identity=26.3440860215054, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI28144899, Length=186, Percent_Identity=26.3440860215054, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1786680, Length=211, Percent_Identity=61.1374407582938, Blast_Score=268, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17552384, Length=188, Percent_Identity=47.3404255319149, Blast_Score=184, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17537943, Length=191, Percent_Identity=34.0314136125654, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17567503, Length=187, Percent_Identity=29.9465240641711, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17533833, Length=185, Percent_Identity=26.4864864864865, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17550688, Length=185, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320432, Length=201, Percent_Identity=48.2587064676617, Blast_Score=198, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6321018, Length=189, Percent_Identity=43.9153439153439, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322828, Length=188, Percent_Identity=28.1914893617021, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI22026816, Length=183, Percent_Identity=46.9945355191257, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI17737899, Length=187, Percent_Identity=43.3155080213904, Blast_Score=146, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24645822, Length=187, Percent_Identity=43.3155080213904, Blast_Score=146, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24663208, Length=217, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17647141, Length=217, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI221459597, Length=185, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356893, Length=185, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 1640 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 847 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006259
- InterPro:   IPR000850
- InterPro:   IPR007862 [H]

Pfam domain/function: PF00406 ADK; PF05191 ADK_lid [H]

EC number: =2.7.4.3 [H]

Molecular weight: Translated: 23998; Mature: 23998

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00113 ADENYLATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRIILLGPPGAGKGTQAQFISKQYDIPQISTGDMLRAAIKEGTELGKKAEGIMKSGGLV
CEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDDLIINLVKERIAKPDCANGCIFDGFPRTIPQAEALIEAGVDIDHVVEISVPDDEIVSR
HHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHCCCHHHEEEEECCHHHHHHH
LSGRRQHPGSGRVYHLKYNPPKQEGLDDETGEPLIQRDDDKEETIRDRLATYHEQTSTLV
HHCCCCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GFYQNKAKEDANAPKYHQFDGTKDIEVVKENILSALKG
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMRIILLGPPGAGKGTQAQFISKQYDIPQISTGDMLRAAIKEGTELGKKAEGIMKSGGLV
CEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDDLIINLVKERIAKPDCANGCIFDGFPRTIPQAEALIEAGVDIDHVVEISVPDDEIVSR
HHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHCCCHHHEEEEECCHHHHHHH
LSGRRQHPGSGRVYHLKYNPPKQEGLDDETGEPLIQRDDDKEETIRDRLATYHEQTSTLV
HHCCCCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GFYQNKAKEDANAPKYHQFDGTKDIEVVKENILSALKG
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA