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The map label for this gene is lpxC

Identifier: 148652342

GI number: 148652342

Start: 634258

End: 635151

Strand: Direct

Name: lpxC

Synonym: PsycPRwf_0530

Alternate gene names: 148652342

Gene position: 634258-635151 (Clockwise)

Preceding gene: 148652341

Following gene: 148652344

Centisome position: 21.29

GC content: 41.39

Gene sequence:

>894_bases
ATGAAACAACGCACCTTAAAACAGCCCATAACTGTCGTTGGGATAGGACTACATAGCGGTCAAGATGTCACCTTAACCTT
GCAGCCTAGTGAGGTAAATACGGGGATTAGATTTTTGCGCACCGATATTGAGGATGCTCCCTTGATAGCGGCCGATGCAT
TTTTGGTGACAGACACGGTCATGTCCTCTAATCTGATGGTAAATGGCATAAAAATTGGCACAGTCGAGCACCTATTAAGT
GCTTTGGCAGGCTTTGGTATAGATAACCTACTGATTAAGGTGTCTGATGCTGAGATTCCTATTATGGATGGCAGTGCTGC
CAATTACGTCACCTTATTACTCGAGGCAGGTATAGAGGAGCAAGCCGCTCCTAAGCAGTTTATGAAAATATTAAAACCTG
TCAAAGTAGTCGAGGGAGATAAGTGGGCACAACTTGAGCCTTACGACGGCTTTAGCTTAGATTTTGAAATTGACTTTAAT
CATCCTGGTATTCCAAAAGATACCCAGCGCTATCGCTTTGAATTCTCCTTGCATAACTATATCGAGAATGTGGGCAATGC
TCGAACCTTTGGATTTATGCGAGATATTGAGCATCTGCAGAAGAATAATCTGGCGCTAGGCGGCAGTTTGGACAATGCAA
TTGTGCTTGATGATAACGGCATTATGAACAAAGAGGGCCTAAGACATCAAGAAGAGTTCGTGCGTCATAAGATTTTAGAT
GCTATTGGTGATTTATATTTGGCTAAATACAGTCTGATTGGCGGTTTTTCTGCTTACAAATCTGGTCATGCATTGAACAA
TAAGCTCATTAGAGAGGTATATAATGACCCCAATAACTTTGAAATTGTAACAATTTATGACACATCTTCAGTGGCGAGAG
CTTATGAAATTTAA

Upstream 100 bases:

>100_bases
GGATATAAGGTAATATTATTGAGCGACTGTGCTAGAATTCTTTTTATTTTGCTCGTTAATGACAGCAACTCATTGACGAC
AGCAATAAGGTACCGGCTTT

Downstream 100 bases:

>100_bases
ATTTCAAGTAAAATCTTCAATAATTTTTAGATTTTCTGGTCGTTTTTTTAGATTTTAAGCAACAATATGGAAATATAAAA
AAAGGTGAAACTCAGGTTTC

Product: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase

Products: NA

Alternate protein names: UDP-3-O-acyl-GlcNAc deacetylase

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKQRTLKQPITVVGIGLHSGQDVTLTLQPSEVNTGIRFLRTDIEDAPLIAADAFLVTDTVMSSNLMVNGIKIGTVEHLLS
ALAGFGIDNLLIKVSDAEIPIMDGSAANYVTLLLEAGIEEQAAPKQFMKILKPVKVVEGDKWAQLEPYDGFSLDFEIDFN
HPGIPKDTQRYRFEFSLHNYIENVGNARTFGFMRDIEHLQKNNLALGGSLDNAIVLDDNGIMNKEGLRHQEEFVRHKILD
AIGDLYLAKYSLIGGFSAYKSGHALNNKLIREVYNDPNNFEIVTIYDTSSVARAYEI

Sequences:

>Translated_297_residues
MKQRTLKQPITVVGIGLHSGQDVTLTLQPSEVNTGIRFLRTDIEDAPLIAADAFLVTDTVMSSNLMVNGIKIGTVEHLLS
ALAGFGIDNLLIKVSDAEIPIMDGSAANYVTLLLEAGIEEQAAPKQFMKILKPVKVVEGDKWAQLEPYDGFSLDFEIDFN
HPGIPKDTQRYRFEFSLHNYIENVGNARTFGFMRDIEHLQKNNLALGGSLDNAIVLDDNGIMNKEGLRHQEEFVRHKILD
AIGDLYLAKYSLIGGFSAYKSGHALNNKLIREVYNDPNNFEIVTIYDTSSVARAYEI
>Mature_297_residues
MKQRTLKQPITVVGIGLHSGQDVTLTLQPSEVNTGIRFLRTDIEDAPLIAADAFLVTDTVMSSNLMVNGIKIGTVEHLLS
ALAGFGIDNLLIKVSDAEIPIMDGSAANYVTLLLEAGIEEQAAPKQFMKILKPVKVVEGDKWAQLEPYDGFSLDFEIDFN
HPGIPKDTQRYRFEFSLHNYIENVGNARTFGFMRDIEHLQKNNLALGGSLDNAIVLDDNGIMNKEGLRHQEEFVRHKILD
AIGDLYLAKYSLIGGFSAYKSGHALNNKLIREVYNDPNNFEIVTIYDTSSVARAYEI

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell

COG id: COG0774

COG function: function code M; UDP-3-O-acyl-N-acetylglucosamine deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxC family

Homologues:

Organism=Escherichia coli, GI1786285, Length=297, Percent_Identity=52.5252525252525, Blast_Score=324, Evalue=5e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXC_PSYWF (A5WCU4)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279435.1
- ProteinModelPortal:   A5WCU4
- SMR:   A5WCU4
- STRING:   A5WCU4
- GeneID:   5206424
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0530
- eggNOG:   COG0774
- HOGENOM:   HBG482342
- OMA:   KAYKSGH
- ProtClustDB:   PRK13186
- BioCyc:   PSP56811:PSYCPRWF_0530-MONOMER
- HAMAP:   MF_00388
- InterPro:   IPR020568
- InterPro:   IPR004463
- InterPro:   IPR011334
- InterPro:   IPR015870
- Gene3D:   G3DSA:3.30.1700.10
- Gene3D:   G3DSA:3.30.230.20
- TIGRFAMs:   TIGR00325

Pfam domain/function: PF03331 LpxC; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: 3.5.1.-

Molecular weight: Translated: 33016; Mature: 33016

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRTLKQPITVVGIGLHSGQDVTLTLQPSEVNTGIRFLRTDIEDAPLIAADAFLVTDTV
CCCCCHHCCEEEEEEEECCCCEEEEEEECCCCCCCHHHEECCCCCCCEEEECHHHHHHHH
MSSNLMVNGIKIGTVEHLLSALAGFGIDNLLIKVSDAEIPIMDGSAANYVTLLLEAGIEE
HHCCEEEEEEEECHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCC
QAAPKQFMKILKPVKVVEGDKWAQLEPYDGFSLDFEIDFNHPGIPKDTQRYRFEFSLHNY
CCCHHHHHHHHHHHEEECCCCCCEECCCCCCEEEEEEECCCCCCCCCCHHEEEEEHHHHH
IENVGNARTFGFMRDIEHLQKNNLALGGSLDNAIVLDDNGIMNKEGLRHQEEFVRHKILD
HHHCCCCHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
AIGDLYLAKYSLIGGFSAYKSGHALNNKLIREVYNDPNNFEIVTIYDTSSVARAYEI
HHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MKQRTLKQPITVVGIGLHSGQDVTLTLQPSEVNTGIRFLRTDIEDAPLIAADAFLVTDTV
CCCCCHHCCEEEEEEEECCCCEEEEEEECCCCCCCHHHEECCCCCCCEEEECHHHHHHHH
MSSNLMVNGIKIGTVEHLLSALAGFGIDNLLIKVSDAEIPIMDGSAANYVTLLLEAGIEE
HHCCEEEEEEEECHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCC
QAAPKQFMKILKPVKVVEGDKWAQLEPYDGFSLDFEIDFNHPGIPKDTQRYRFEFSLHNY
CCCHHHHHHHHHHHEEECCCCCCEECCCCCCEEEEEEECCCCCCCCCCHHEEEEEHHHHH
IENVGNARTFGFMRDIEHLQKNNLALGGSLDNAIVLDDNGIMNKEGLRHQEEFVRHKILD
HHHCCCCHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
AIGDLYLAKYSLIGGFSAYKSGHALNNKLIREVYNDPNNFEIVTIYDTSSVARAYEI
HHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on carbon-nitrogen bonds, other than peptide bonds; In linear amides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA