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The map label for this gene is murA

Identifier: 148652313

GI number: 148652313

Start: 595457

End: 596755

Strand: Direct

Name: murA

Synonym: PsycPRwf_0501

Alternate gene names: 148652313

Gene position: 595457-596755 (Clockwise)

Preceding gene: 148652312

Following gene: 148652314

Centisome position: 19.99

GC content: 50.65

Gene sequence:

>1299_bases
ATGGACCAATTCTTAATCACCGGCCGCAGCCGCATTGCAGGCGAAGTCACCATCTCAGGCGCAAAAAATGCCGCCTTGCC
ACTTCTTGCTGCCATGATATTGGCAGAGACGCCGACAACATTGAATAATGTGCCTTCACTACAAGATGTGCGCACGTTAA
TCAAGCTGATTGCAGGACTTGGCATTCGTATTGAAAAGCAAGGCGATACGGTAACCTGTGACACCAGCACCATCGAAAAC
TACTTTGCCCCTTATGAGCTGGTAAAAACCATGCGTGCCTCTATCTTGGTTTTAGGTCCTTTGTTGGCCCGCTTTGGTGA
AGCTGAAGTATCACTGCCTGGTGGCTGCGCTATCGGCTCACGTCCAGTGGATCAGCATCTAAAAGCCTTTAAAGCGATGG
GTGCTGAGATCACTGTAGAAAACGGCTATGTTAAAGCCCGTGCCCCTGAAGGTGGCCGCTTGATTGGCTGTGAATTCAGC
TTCGATATGGTAACAGTGGGTGGTACAGAAAATGTGCTGATTGCCGCCACTTTAGCCAAAGGTACCACGGTATTAGAGAA
CTGCGCACGTGAGCCAGAAGTGGTTGATTTGGCCAATATGTTGGTGGCTATGGGCGCTAAGGTTAGCGGTATTGGCACGG
CTACCTTGACCATTGAAGGCGTAGACAGCCTACAGGGCTGTGAGTACTCCGTGGTGCCTGATCGCATCGAGACCGGCTCT
TATTTGGCAGGCGCTTTGATGACCGAAGGTGATGTGACTACTAAGAATACTGACCCGGCATTATTACAGCCTGTGCTACA
AAAGTTTGAAGAAATGGGCGCCATTATTACCACAGGTGATGACTGGATTCGTGCTCAAATGACCGGCCGTCCCAAGCCAG
TTGATATTCGTACCCAGCCACACCCAGGCTTCCCAACCGACATGCAGGCCCAATTAATGGCGGTATGCTGCTTAGCAGAG
GGCACCAGCACCATTAGTGAAAACATCTTTGAAAACCGCTATATGCATGTGCCAGAGCTTAAGCGCATGGGCGCAGATAT
CCAAGTTGACGGTCACACAGCCATTATCCGCGGTGTAGATAGCTTCAATGCGGCACCAGTTATGGCCACTGACTTACGCG
CCTCAATGTCACTGGTAATGGCCGCGGCGGCTGCCGAAGGCGAGACGCTGATTGACCGTATTTATCATATTGACCGTGGC
TATGAAAACGTAGAGGAAAAGCTACGTGGCCTTGGGGTAAATATCGAACGTGTCAATCCGGTAACTGATGCAGCAGAAGC
CGATAGCTTGGATGACTAA

Upstream 100 bases:

>100_bases
TCTTTGATGGTCAGGGTTGTCTTATTTACCGCACCCTGTGTATTTTTAGTCACTTATTTAGTGTAATTTTTATTGAAACA
ATCGTTTAGGACAGTATTCA

Downstream 100 bases:

>100_bases
AGCCCGCTTGGTTATAACAAAAATACTCTCATCTTATTAAGACATACCCGACTATGACTGAAACAAATGAAATATTAAAC
CAAGCCGATAGTGACTATGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MDQFLITGRSRIAGEVTISGAKNAALPLLAAMILAETPTTLNNVPSLQDVRTLIKLIAGLGIRIEKQGDTVTCDTSTIEN
YFAPYELVKTMRASILVLGPLLARFGEAEVSLPGGCAIGSRPVDQHLKAFKAMGAEITVENGYVKARAPEGGRLIGCEFS
FDMVTVGGTENVLIAATLAKGTTVLENCAREPEVVDLANMLVAMGAKVSGIGTATLTIEGVDSLQGCEYSVVPDRIETGS
YLAGALMTEGDVTTKNTDPALLQPVLQKFEEMGAIITTGDDWIRAQMTGRPKPVDIRTQPHPGFPTDMQAQLMAVCCLAE
GTSTISENIFENRYMHVPELKRMGADIQVDGHTAIIRGVDSFNAAPVMATDLRASMSLVMAAAAAEGETLIDRIYHIDRG
YENVEEKLRGLGVNIERVNPVTDAAEADSLDD

Sequences:

>Translated_432_residues
MDQFLITGRSRIAGEVTISGAKNAALPLLAAMILAETPTTLNNVPSLQDVRTLIKLIAGLGIRIEKQGDTVTCDTSTIEN
YFAPYELVKTMRASILVLGPLLARFGEAEVSLPGGCAIGSRPVDQHLKAFKAMGAEITVENGYVKARAPEGGRLIGCEFS
FDMVTVGGTENVLIAATLAKGTTVLENCAREPEVVDLANMLVAMGAKVSGIGTATLTIEGVDSLQGCEYSVVPDRIETGS
YLAGALMTEGDVTTKNTDPALLQPVLQKFEEMGAIITTGDDWIRAQMTGRPKPVDIRTQPHPGFPTDMQAQLMAVCCLAE
GTSTISENIFENRYMHVPELKRMGADIQVDGHTAIIRGVDSFNAAPVMATDLRASMSLVMAAAAAEGETLIDRIYHIDRG
YENVEEKLRGLGVNIERVNPVTDAAEADSLDD
>Mature_432_residues
MDQFLITGRSRIAGEVTISGAKNAALPLLAAMILAETPTTLNNVPSLQDVRTLIKLIAGLGIRIEKQGDTVTCDTSTIEN
YFAPYELVKTMRASILVLGPLLARFGEAEVSLPGGCAIGSRPVDQHLKAFKAMGAEITVENGYVKARAPEGGRLIGCEFS
FDMVTVGGTENVLIAATLAKGTTVLENCAREPEVVDLANMLVAMGAKVSGIGTATLTIEGVDSLQGCEYSVVPDRIETGS
YLAGALMTEGDVTTKNTDPALLQPVLQKFEEMGAIITTGDDWIRAQMTGRPKPVDIRTQPHPGFPTDMQAQLMAVCCLAE
GTSTISENIFENRYMHVPELKRMGADIQVDGHTAIIRGVDSFNAAPVMATDLRASMSLVMAAAAAEGETLIDRIYHIDRG
YENVEEKLRGLGVNIERVNPVTDAAEADSLDD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=55.2380952380952, Blast_Score=472, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_PSYWF (A5WCR5)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279406.1
- ProteinModelPortal:   A5WCR5
- SMR:   A5WCR5
- STRING:   A5WCR5
- GeneID:   5205533
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0501
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   PSP56811:PSYCPRWF_0501-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 46073; Mature: 46073

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQFLITGRSRIAGEVTISGAKNAALPLLAAMILAETPTTLNNVPSLQDVRTLIKLIAGL
CCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
GIRIEKQGDTVTCDTSTIENYFAPYELVKTMRASILVLGPLLARFGEAEVSLPGGCAIGS
CEEEECCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
RPVDQHLKAFKAMGAEITVENGYVKARAPEGGRLIGCEFSFDMVTVGGTENVLIAATLAK
CCHHHHHHHHHHCCCEEEEECCEEEEECCCCCEEEEEEEEEEEEEECCCCCEEEEEEECC
GTTVLENCAREPEVVDLANMLVAMGAKVSGIGTATLTIEGVDSLQGCEYSVVPDRIETGS
CHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCC
YLAGALMTEGDVTTKNTDPALLQPVLQKFEEMGAIITTGDDWIRAQMTGRPKPVDIRTQP
HHHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEEECCC
HPGFPTDMQAQLMAVCCLAEGTSTISENIFENRYMHVPELKRMGADIQVDGHTAIIRGVD
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCCEEECCCEEEEEECC
SFNAAPVMATDLRASMSLVMAAAAAEGETLIDRIYHIDRGYENVEEKLRGLGVNIERVNP
CCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCC
VTDAAEADSLDD
CCCCCCCCCCCC
>Mature Secondary Structure
MDQFLITGRSRIAGEVTISGAKNAALPLLAAMILAETPTTLNNVPSLQDVRTLIKLIAGL
CCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
GIRIEKQGDTVTCDTSTIENYFAPYELVKTMRASILVLGPLLARFGEAEVSLPGGCAIGS
CEEEECCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
RPVDQHLKAFKAMGAEITVENGYVKARAPEGGRLIGCEFSFDMVTVGGTENVLIAATLAK
CCHHHHHHHHHHCCCEEEEECCEEEEECCCCCEEEEEEEEEEEEEECCCCCEEEEEEECC
GTTVLENCAREPEVVDLANMLVAMGAKVSGIGTATLTIEGVDSLQGCEYSVVPDRIETGS
CHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCC
YLAGALMTEGDVTTKNTDPALLQPVLQKFEEMGAIITTGDDWIRAQMTGRPKPVDIRTQP
HHHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEEECCC
HPGFPTDMQAQLMAVCCLAEGTSTISENIFENRYMHVPELKRMGADIQVDGHTAIIRGVD
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHCCCCEEECCCEEEEEECC
SFNAAPVMATDLRASMSLVMAAAAAEGETLIDRIYHIDRGYENVEEKLRGLGVNIERVNP
CCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCC
VTDAAEADSLDD
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA