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The map label for this gene is ubiA [H]

Identifier: 148652294

GI number: 148652294

Start: 576465

End: 577412

Strand: Direct

Name: ubiA [H]

Synonym: PsycPRwf_0482

Alternate gene names: 148652294

Gene position: 576465-577412 (Clockwise)

Preceding gene: 148652293

Following gene: 148652295

Centisome position: 19.35

GC content: 47.89

Gene sequence:

>948_bases
ATGACTACCAATTTTAAAAATAAACTTCAAGCCTATATTCACTTAACCCGCTTTGATAAGCCTGTCGGGATTGAGCTGCT
GCTGTGGCCCACGCTCTGGGCAGTATTATTGGCAGCTTTTGGCCAGGCCATCGCTCAGGCGCCCTCAAGTGTAACAGCAT
CACCAAGTGTGCTGCCGGCTTGGTCGGTACTATTGATTTTCGCGCTTGGTGCGATATTGATGCGCGCTGCAGGCTGCGCG
ATTAATGATTTTGCCGATCGTAAAGTGGATGGTTCGGTAACACGCACCAAAGGGCGTCCTTTAGCCGATGGCAGATTGAC
CGGACGCGAGGCGGTAGGGGCATTTTTAGTCTTGTCGCTTATCAGTGCCAGTTTATTGTTTTGGCTGCCCATTGCGGTGT
TTTACTGGTCAATCGGCGCCCTTATATTGGCGTTTATTTATCCCTTTATGAAGCGGTTCACCCATTTGCCGCAGGTGTTC
TTAGCGGCCGCATTTGGATGGGCCATTCCCATGGCTTATGTGGCCATACAAGGGCAGCCGGATGTGTGGTGCTGGCTGTT
ATTTATTGCTTACATGTGCTGGACGGTAGCCTATGATACTCAGTACGCTATGGCAGATCGTGATGATGATTTAAAAATTG
GGGTGAAGTCCACGGCGATATTATTTGGCCGCTATGATGTGGTCATCATCTCGTTACTGCAAGTGGCTTTTTTGGCAATA
ATGGGTGTGGTTTTTTATCATTATTTTGCACCCACAAGCCTTGGGTTAATTCCTGTTTATGCCTTGGGACTAGTTGCCAT
TTTGTTTGCTCAGCAAAATAGGGCCTGTGCAACTCGTGAGCCTATGGCCTGTTTTCAGGCGTTTTTAGCCAATGTTTGGG
TGGGACGATATGTGTTTTTAGTGGTGCTTTTGAGCAGCCTTTACATCCAGTTTAATGGCCTCACTTAA

Upstream 100 bases:

>100_bases
AATTTAATGGTTTTTAAAGCGCTGCTGATTGTCGCCGCTCTTGAATTTATTTAACCCCCCAACCGCTTCGGTGTAACTGA
TTTAGCTTTGCTGACTTGCT

Downstream 100 bases:

>100_bases
CTTTTTTACACCCAAGAGAGACTCATGGCAAAACCCTTTAAAAGCGATTTAAGCCTTGACGCTAAACTGGCAGCGCATCA
GCGGTTTGAACAAAATCTGC

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTTNFKNKLQAYIHLTRFDKPVGIELLLWPTLWAVLLAAFGQAIAQAPSSVTASPSVLPAWSVLLIFALGAILMRAAGCA
INDFADRKVDGSVTRTKGRPLADGRLTGREAVGAFLVLSLISASLLFWLPIAVFYWSIGALILAFIYPFMKRFTHLPQVF
LAAAFGWAIPMAYVAIQGQPDVWCWLLFIAYMCWTVAYDTQYAMADRDDDLKIGVKSTAILFGRYDVVIISLLQVAFLAI
MGVVFYHYFAPTSLGLIPVYALGLVAILFAQQNRACATREPMACFQAFLANVWVGRYVFLVVLLSSLYIQFNGLT

Sequences:

>Translated_315_residues
MTTNFKNKLQAYIHLTRFDKPVGIELLLWPTLWAVLLAAFGQAIAQAPSSVTASPSVLPAWSVLLIFALGAILMRAAGCA
INDFADRKVDGSVTRTKGRPLADGRLTGREAVGAFLVLSLISASLLFWLPIAVFYWSIGALILAFIYPFMKRFTHLPQVF
LAAAFGWAIPMAYVAIQGQPDVWCWLLFIAYMCWTVAYDTQYAMADRDDDLKIGVKSTAILFGRYDVVIISLLQVAFLAI
MGVVFYHYFAPTSLGLIPVYALGLVAILFAQQNRACATREPMACFQAFLANVWVGRYVFLVVLLSSLYIQFNGLT
>Mature_314_residues
TTNFKNKLQAYIHLTRFDKPVGIELLLWPTLWAVLLAAFGQAIAQAPSSVTASPSVLPAWSVLLIFALGAILMRAAGCAI
NDFADRKVDGSVTRTKGRPLADGRLTGREAVGAFLVLSLISASLLFWLPIAVFYWSIGALILAFIYPFMKRFTHLPQVFL
AAAFGWAIPMAYVAIQGQPDVWCWLLFIAYMCWTVAYDTQYAMADRDDDLKIGVKSTAILFGRYDVVIISLLQVAFLAIM
GVVFYHYFAPTSLGLIPVYALGLVAILFAQQNRACATREPMACFQAFLANVWVGRYVFLVVLLSSLYIQFNGLT

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=305, Percent_Identity=36.0655737704918, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1790473, Length=300, Percent_Identity=49, Blast_Score=256, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17553718, Length=314, Percent_Identity=33.7579617834395, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI32565247, Length=311, Percent_Identity=34.0836012861736, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17553720, Length=203, Percent_Identity=37.9310344827586, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32565245, Length=161, Percent_Identity=39.7515527950311, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32565243, Length=160, Percent_Identity=40, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324370, Length=302, Percent_Identity=33.4437086092715, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21355567, Length=303, Percent_Identity=34.983498349835, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34836; Mature: 34704

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNFKNKLQAYIHLTRFDKPVGIELLLWPTLWAVLLAAFGQAIAQAPSSVTASPSVLPA
CCCCHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
WSVLLIFALGAILMRAAGCAINDFADRKVDGSVTRTKGRPLADGRLTGREAVGAFLVLSL
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ISASLLFWLPIAVFYWSIGALILAFIYPFMKRFTHLPQVFLAAAFGWAIPMAYVAIQGQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
DVWCWLLFIAYMCWTVAYDTQYAMADRDDDLKIGVKSTAILFGRYDVVIISLLQVAFLAI
CHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHH
MGVVFYHYFAPTSLGLIPVYALGLVAILFAQQNRACATREPMACFQAFLANVWVGRYVFL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVLLSSLYIQFNGLT
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTNFKNKLQAYIHLTRFDKPVGIELLLWPTLWAVLLAAFGQAIAQAPSSVTASPSVLPA
CCCHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
WSVLLIFALGAILMRAAGCAINDFADRKVDGSVTRTKGRPLADGRLTGREAVGAFLVLSL
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ISASLLFWLPIAVFYWSIGALILAFIYPFMKRFTHLPQVFLAAAFGWAIPMAYVAIQGQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
DVWCWLLFIAYMCWTVAYDTQYAMADRDDDLKIGVKSTAILFGRYDVVIISLLQVAFLAI
CHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHH
MGVVFYHYFAPTSLGLIPVYALGLVAILFAQQNRACATREPMACFQAFLANVWVGRYVFL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVLLSSLYIQFNGLT
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA