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The map label for this gene is fabD [H]

Identifier: 148652268

GI number: 148652268

Start: 540030

End: 541028

Strand: Direct

Name: fabD [H]

Synonym: PsycPRwf_0456

Alternate gene names: 148652268

Gene position: 540030-541028 (Clockwise)

Preceding gene: 148652267

Following gene: 148652269

Centisome position: 18.13

GC content: 45.65

Gene sequence:

>999_bases
ATGTCACTAAAAGCGTCGCAAGCAGTTAAAAAACAAGGTCAACTGGATGTGCCTCGTCGCATTGCGGTTGTTTTTCCTGG
GCAAGGTTCACAAACTGTCGGTATGCTAAATGAGCTGAGCGAAGCGTATCCTATCGTCAAAGAGACGTTTGCTGAAGCGA
GTGAAGCATTAGGGTTTGATTTGTGGGCAGTGTGTCAAGATGAGGCTGAATTAGGTAAGACTGAGAACACTCAGCCTGCG
TTATTAACCGCCAGTATTGCCGTTTGGCGTATTTTGCAACAAAACACTCAAATTGAACCTCTATTTTTAGCAGGGCACTC
TTTAGGAGAGTACAGCGCCTTGTGTGCTGCGGGCTCAATTAGCTTTGCAGATGCTGTAAAATTGGTTCACGCGCGTGGCC
ACTTTATGCAGCAAGCTGTGGTAGGGGTTGATACTAAGATGGCTGCTGTACTTGGCTTAGATAACAGCCAGGTGATTAGT
ATCTGTGAGCAAGTAGAGAGCAATAATGATGACACCATCGTGAGCGCTGCCAACTTCAATAGCCCAGGTCAAATCGTGGT
TGCGGGCAACTCTGAAGGTGTTGATATCTTAAGCCAACATATCCAATGTATGGGCAAGCGTATAGTGCCGCTCAAGGTGA
GCGTACCTTCGCACTGCGCATTGATGCAGCCAGCCACAGAAGCCTTGGCAGAGAAGCTGGCCGAATGCAAATTTGAGCTG
CCAAGCATTCCTGTAATTCAAAATAAAAACGCCATGGAAGAAAAAACAATCGCCGGTATAAAAAAGGCGTTAACTGAGCA
GCTTAGCCATCCTGTGCTATGGACTCAAACCATGCAAAAACTGGCCGATAAACACATCAATTTAATCATTGAGTGCGGTG
CAGGCACGGTTTTGAGTAATTTGGCAAAAAGACAAGACACGCCTATTGCCACTTATCCTACTGATAAGCCAGAGCGACTC
GCTAAGCTTTTTGATAAGTTAAATAATGAGGATCTATAA

Upstream 100 bases:

>100_bases
ATGGTTAGATATAAGAGCTAAGCCTTACTAATGACCCTTTTATCATTAGTGGCGCTTGGCTCTTTTTTTATGAGTATATT
TAGGGATAAGAAGGCTTATA

Downstream 100 bases:

>100_bases
TGAGTCGTACAATCACTTTAGTTACAGGTGCCAGTCGTGGTATCGGTAAAGCTATTGCCAAGCGTTTTGCTAAGGAAGGT
CACTTTGTGATTGGCACTGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSLKASQAVKKQGQLDVPRRIAVVFPGQGSQTVGMLNELSEAYPIVKETFAEASEALGFDLWAVCQDEAELGKTENTQPA
LLTASIAVWRILQQNTQIEPLFLAGHSLGEYSALCAAGSISFADAVKLVHARGHFMQQAVVGVDTKMAAVLGLDNSQVIS
ICEQVESNNDDTIVSAANFNSPGQIVVAGNSEGVDILSQHIQCMGKRIVPLKVSVPSHCALMQPATEALAEKLAECKFEL
PSIPVIQNKNAMEEKTIAGIKKALTEQLSHPVLWTQTMQKLADKHINLIIECGAGTVLSNLAKRQDTPIATYPTDKPERL
AKLFDKLNNEDL

Sequences:

>Translated_332_residues
MSLKASQAVKKQGQLDVPRRIAVVFPGQGSQTVGMLNELSEAYPIVKETFAEASEALGFDLWAVCQDEAELGKTENTQPA
LLTASIAVWRILQQNTQIEPLFLAGHSLGEYSALCAAGSISFADAVKLVHARGHFMQQAVVGVDTKMAAVLGLDNSQVIS
ICEQVESNNDDTIVSAANFNSPGQIVVAGNSEGVDILSQHIQCMGKRIVPLKVSVPSHCALMQPATEALAEKLAECKFEL
PSIPVIQNKNAMEEKTIAGIKKALTEQLSHPVLWTQTMQKLADKHINLIIECGAGTVLSNLAKRQDTPIATYPTDKPERL
AKLFDKLNNEDL
>Mature_331_residues
SLKASQAVKKQGQLDVPRRIAVVFPGQGSQTVGMLNELSEAYPIVKETFAEASEALGFDLWAVCQDEAELGKTENTQPAL
LTASIAVWRILQQNTQIEPLFLAGHSLGEYSALCAAGSISFADAVKLVHARGHFMQQAVVGVDTKMAAVLGLDNSQVISI
CEQVESNNDDTIVSAANFNSPGQIVVAGNSEGVDILSQHIQCMGKRIVPLKVSVPSHCALMQPATEALAEKLAECKFELP
SIPVIQNKNAMEEKTIAGIKKALTEQLSHPVLWTQTMQKLADKHINLIIECGAGTVLSNLAKRQDTPIATYPTDKPERLA
KLFDKLNNEDL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=296, Percent_Identity=31.7567567567568, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=47.5728155339806, Blast_Score=275, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI71984332, Length=304, Percent_Identity=31.25, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24665753, Length=313, Percent_Identity=30.0319488817891, Blast_Score=117, Evalue=8e-27,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 35825; Mature: 35693

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKASQAVKKQGQLDVPRRIAVVFPGQGSQTVGMLNELSEAYPIVKETFAEASEALGFD
CCCCHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LWAVCQDEAELGKTENTQPALLTASIAVWRILQQNTQIEPLFLAGHSLGEYSALCAAGSI
HHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCC
SFADAVKLVHARGHFMQQAVVGVDTKMAAVLGLDNSQVISICEQVESNNDDTIVSAANFN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCC
SPGQIVVAGNSEGVDILSQHIQCMGKRIVPLKVSVPSHCALMQPATEALAEKLAECKFEL
CCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHCHHHHHHHHHHHHCCCCC
PSIPVIQNKNAMEEKTIAGIKKALTEQLSHPVLWTQTMQKLADKHINLIIECGAGTVLSN
CCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCHHHHH
LAKRQDTPIATYPTDKPERLAKLFDKLNNEDL
HHHHCCCCCEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLKASQAVKKQGQLDVPRRIAVVFPGQGSQTVGMLNELSEAYPIVKETFAEASEALGFD
CCCHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LWAVCQDEAELGKTENTQPALLTASIAVWRILQQNTQIEPLFLAGHSLGEYSALCAAGSI
HHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCC
SFADAVKLVHARGHFMQQAVVGVDTKMAAVLGLDNSQVISICEQVESNNDDTIVSAANFN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCC
SPGQIVVAGNSEGVDILSQHIQCMGKRIVPLKVSVPSHCALMQPATEALAEKLAECKFEL
CCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHCHHHHHHHHHHHHCCCCC
PSIPVIQNKNAMEEKTIAGIKKALTEQLSHPVLWTQTMQKLADKHINLIIECGAGTVLSN
CCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCHHHHH
LAKRQDTPIATYPTDKPERLAKLFDKLNNEDL
HHHHCCCCCEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]