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The map label for this gene is omp38 [H]

Identifier: 148652191

GI number: 148652191

Start: 453804

End: 455015

Strand: Direct

Name: omp38 [H]

Synonym: PsycPRwf_0379

Alternate gene names: 148652191

Gene position: 453804-455015 (Clockwise)

Preceding gene: 148652189

Following gene: 148652192

Centisome position: 15.23

GC content: 45.46

Gene sequence:

>1212_bases
ATGAAACTTAACAAAATTAATCTAGCAATCCTAGCTGCTGCTGTTGCTGCACCAGTTATGGCTACTGCTGGTGTAACTGT
AAGTCCACTATTACTGGGTTATCACTACAGTGAAGCTAACAAAACTCAAGAAAAACAAGGTGAGTTGTTCGGCGCACAAG
GTAACGCCGGTGATTTTAAAAATGCTGACGACACCAAAGGTGGCGTAGCTCAAGAAGACGGTTTATACACTGGTGCCGCT
ATTGGTATCGAACTAACCCCTTCTACTCAGTTCCAAGTTGAATACGGTGTTTCTAACACTGATGCACAAATCGGCGACAC
CAAAGTTGGCGATATGGAACAAGAAATGATCTCTGGTAACTTCCTAGTGGGCTTTGATCAGTTCACAGGCTACCGTGACA
CAGCTTTCCGTCCATACGCTCTAATTGGTGCTGGTCAGTCTAAACTTAAATACGACAGCGACAACAGCAACCGTAAAGCA
GAAACCAAAGACACTATCGGTAACCTAGGTCTAGGTGCTATGTATCGCATCAATGACGCATTAAGCCTACGTGGTGAAGC
GCGTGCGATTCATAACTTCGACAACAACTGGTGGGAAGGTATGGCTCTTGCTGGTCTAGAAGTTGTTCTAGGCGGTCACT
TAGCACCTGCAGTAGTAGCACCACCACAAGCCACTGTTGAACCAACTCCAGTTATCGTTGTTGAAGCAGACCAAGACAGC
GACAATGATGGCGTAATCGACAGACTAGATCAGTGCCCTGACACGCCAGTTAACACCGTTGTTGACGAAAACGGCTGCCC
AGTACAAGTTCAGATCGACGACGAACTGAAAATGGAACTACGTGTATTCTTCGATAACGACAAATCAGTTATCAAAGAGC
AGTACAAACCAGAAATCGCTAAAGTAGCTGAAAAAATGCGTGAGTATCCAAACTCATCAGCTAGCATCGAAGGTCACGCT
TCAAAAACTGGCCCATCAGCTCGCTACAACCAGCGTCTATCTGAAGCCCGTGCTATCGCTGTTAAGACAATGCTAACCAA
CGAATTTGGTGTTGCTCCTAACCGTCTAAGCACAGTTGGTTACGGTTATGACCGTCCAATCGCACCAAACGACACTGAAG
AAGGTCGTGCAATGAACCGTCGTGTATATGCTGTTATCACTGGTAACAAAACCATGACTGTTGATCAAACTAAAGACATG
AACGTTCAATAG

Upstream 100 bases:

>100_bases
AGTATAAATTAGTATCCGGCTTTTCTTTGATAAGTTAGGGTATATATATTAGAGATATTAAGTGTTTTTTGCACACAAAC
CGTCCCTTTGGAGGAAGTTT

Downstream 100 bases:

>100_bases
AATCTTGTCTATGTTTTAGTAGTTATTTAAAAAAAAGCTGCCACATTGGTGGCTTTTTTTGTTTTATATTATGAGTAACC
TCTTCATTTTTCTTAAAGCA

Product: OmpA/MotB domain-containing protein

Products: NA

Alternate protein names: Outer membrane protein ompA; Outer membrane protein ompAb [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKLNKINLAILAAAVAAPVMATAGVTVSPLLLGYHYSEANKTQEKQGELFGAQGNAGDFKNADDTKGGVAQEDGLYTGAA
IGIELTPSTQFQVEYGVSNTDAQIGDTKVGDMEQEMISGNFLVGFDQFTGYRDTAFRPYALIGAGQSKLKYDSDNSNRKA
ETKDTIGNLGLGAMYRINDALSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVVAPPQATVEPTPVIVVEADQDS
DNDGVIDRLDQCPDTPVNTVVDENGCPVQVQIDDELKMELRVFFDNDKSVIKEQYKPEIAKVAEKMREYPNSSASIEGHA
SKTGPSARYNQRLSEARAIAVKTMLTNEFGVAPNRLSTVGYGYDRPIAPNDTEEGRAMNRRVYAVITGNKTMTVDQTKDM
NVQ

Sequences:

>Translated_403_residues
MKLNKINLAILAAAVAAPVMATAGVTVSPLLLGYHYSEANKTQEKQGELFGAQGNAGDFKNADDTKGGVAQEDGLYTGAA
IGIELTPSTQFQVEYGVSNTDAQIGDTKVGDMEQEMISGNFLVGFDQFTGYRDTAFRPYALIGAGQSKLKYDSDNSNRKA
ETKDTIGNLGLGAMYRINDALSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVVAPPQATVEPTPVIVVEADQDS
DNDGVIDRLDQCPDTPVNTVVDENGCPVQVQIDDELKMELRVFFDNDKSVIKEQYKPEIAKVAEKMREYPNSSASIEGHA
SKTGPSARYNQRLSEARAIAVKTMLTNEFGVAPNRLSTVGYGYDRPIAPNDTEEGRAMNRRVYAVITGNKTMTVDQTKDM
NVQ
>Mature_403_residues
MKLNKINLAILAAAVAAPVMATAGVTVSPLLLGYHYSEANKTQEKQGELFGAQGNAGDFKNADDTKGGVAQEDGLYTGAA
IGIELTPSTQFQVEYGVSNTDAQIGDTKVGDMEQEMISGNFLVGFDQFTGYRDTAFRPYALIGAGQSKLKYDSDNSNRKA
ETKDTIGNLGLGAMYRINDALSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVVAPPQATVEPTPVIVVEADQDS
DNDGVIDRLDQCPDTPVNTVVDENGCPVQVQIDDELKMELRVFFDNDKSVIKEQYKPEIAKVAEKMREYPNSSASIEGHA
SKTGPSARYNQRLSEARAIAVKTMLTNEFGVAPNRLSTVGYGYDRPIAPNDTEEGRAMNRRVYAVITGNKTMTVDQTKDM
NVQ

Specific function: Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochr

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=107, Percent_Identity=37.3831775700935, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 43599; Mature: 43599

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00560 CARBOXYPEPT_SER_HIS ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNKINLAILAAAVAAPVMATAGVTVSPLLLGYHYSEANKTQEKQGELFGAQGNAGDFK
CCCCHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEECCCCCCHHHHCCEECCCCCCCCCC
NADDTKGGVAQEDGLYTGAAIGIELTPSTQFQVEYGVSNTDAQIGDTKVGDMEQEMISGN
CCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCC
FLVGFDQFTGYRDTAFRPYALIGAGQSKLKYDSDNSNRKAETKDTIGNLGLGAMYRINDA
EEEEEHHHCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHCCCCCEEEEECHH
LSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVVAPPQATVEPTPVIVVEADQDS
HHCCCCHHEECCCCCCHHCCHHHHCCCEEECCCCCCEEECCCCCCCCCCCEEEEECCCCC
DNDGVIDRLDQCPDTPVNTVVDENGCPVQVQIDDELKMELRVFFDNDKSVIKEQYKPEIA
CCCCHHHHHHCCCCCCCHHEECCCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHCCHHH
KVAEKMREYPNSSASIEGHASKTGPSARYNQRLSEARAIAVKTMLTNEFGVAPNRLSTVG
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
YGYDRPIAPNDTEEGRAMNRRVYAVITGNKTMTVDQTKDMNVQ
CCCCCCCCCCCCCCCHHCCCEEEEEEECCEEEEEECCCCCCCC
>Mature Secondary Structure
MKLNKINLAILAAAVAAPVMATAGVTVSPLLLGYHYSEANKTQEKQGELFGAQGNAGDFK
CCCCHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEECCCCCCHHHHCCEECCCCCCCCCC
NADDTKGGVAQEDGLYTGAAIGIELTPSTQFQVEYGVSNTDAQIGDTKVGDMEQEMISGN
CCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCC
FLVGFDQFTGYRDTAFRPYALIGAGQSKLKYDSDNSNRKAETKDTIGNLGLGAMYRINDA
EEEEEHHHCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHCCCCCEEEEECHH
LSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVVAPPQATVEPTPVIVVEADQDS
HHCCCCHHEECCCCCCHHCCHHHHCCCEEECCCCCCEEECCCCCCCCCCCEEEEECCCCC
DNDGVIDRLDQCPDTPVNTVVDENGCPVQVQIDDELKMELRVFFDNDKSVIKEQYKPEIA
CCCCHHHHHHCCCCCCCHHEECCCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHCCHHH
KVAEKMREYPNSSASIEGHASKTGPSARYNQRLSEARAIAVKTMLTNEFGVAPNRLSTVG
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
YGYDRPIAPNDTEEGRAMNRRVYAVITGNKTMTVDQTKDMNVQ
CCCCCCCCCCCCCCCHHCCCEEEEEEECCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA