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The map label for this gene is yicO [C]

Identifier: 148643796

GI number: 148643796

Start: 1788573

End: 1789973

Strand: Reverse

Name: yicO [C]

Synonym: Msm_1736

Alternate gene names: 148643796

Gene position: 1789973-1788573 (Counterclockwise)

Preceding gene: 148643798

Following gene: 148643794

Centisome position: 96.59

GC content: 35.97

Gene sequence:

>1401_bases
ATGTCTAAGTTAGATGCTTTTTTTAAATTTAAAGAAAATAATACAGACGTGAAAACTGAAATCATTGCAGGTATTACAAT
TTTTCTGGCTATGGCTTACATATTAATTGTAAACCCTGCAATGTTAAGTGAAACTGGAATGGACATACAAGGAGTATTTA
TTGCAACTGCACTTTCAGCTGCAATAGCTACAATATTGATGGGATATATAGCAAACTACCCATATGCACTGGCTGCAGGA
ATGGGTCTTAACGCATTTTTCACATATACCGTAGTACTTACTATGGGATACAGCTGGGAATATGCACTTTTAGCTATCTT
TGTCTCAGGTATAATCTTTCTGGTTATCTCACTTACTTCCCTACGTGAAAAATTATTCTATTCAATTCCTGACTCTTTAA
GATTCGGTATATCAATAGGTATAGGTTTATTTATCCTTGCATTAGGTTTAAGCAACCTCGGAATCCTGTCATACTCTTCA
CAGGTAATAAATATCGGAGATGCAAACTGGGCCACACAGCTAATAGGACTTGGAAGCGCTTCAACTATTTTTACTCTCGG
AAACCTTTTGGCATTAATCTGTTTTGTCATCATAATGGTTTTAATGAAGAAAAATGTAAAAGGAAACATTCTAATCGGAA
TTATTGCAACATACATTATCGGAGTTGTTTTAGAACTGGCAGGATGTCCTGTTTTACCTGACCAGTCATTAATACCAACA
GCTATAATCAACAGCAATCTGGGCGGATCACTTGGTAATGTTGCATTTAAATTCGGAGAAGCTAGCGGAGTATTTACCGG
AGTAAGAGCATTTATTGACTTTATAATCATTGCCGTCACATTTCTGGTAATCTCTTTATTTGATACAATGGGAACCTTAA
CTGCACTTACAACAAAAGTTGACGGATATGATGAAAACGGCAAACTGCCAAGACTTAAAAAGGTTTTAAGTGTAGATGCA
CTCGGACCTATTATAGGGTCCGTTTTAGGTACTTCACCTGTAGTTACATACATTGAAAGTTCTACAGGTATTATGGAAGG
AGGAAGAACCGGTCTTACAGCTATTGTAGTTGGTATTTTATTCCTGCTTGCAATTCCGTTTGCACCGATATTTACAATCA
TCCCAACCTTTGCAGTAGCTCCTGCACTTGTTGTTGTAGGTATCTTAATGTGCGGACTGTACAAAAACCTTGATACAGGC
AATCTTTCTGATCTGATTCCTGCACTTGCTGCCATTATTGTAACTCCACTTACCCAAAGTATTACAACAGGTATTATTGC
AGGTGTATTTGCATTTGTTATTGTTAAAGTCTTATTCGGTAAAGCAAAAGAAATATCCAAAGCAATGTGGATTTTATTTG
CACTTTTATTCATTTATATGGTTTTAGAGTTCATAATGTAA

Upstream 100 bases:

>100_bases
TAAAAATAAATTACAATTTGAATATACAGCCTAAAAAAACCGAAAGAAACTGAACTTAAATATAAAAACTTATAAAGCAT
TATTTAAAAAAGATAATAAT

Downstream 100 bases:

>100_bases
GAACTCTAACTTTTTTTTATTTTTTGTCAAAATTTTTTTATTAATTAAATTGCAAAATCAGCTAATTAAATGATAAGTTA
TTAAAAAATTAGCTTATTTA

Product: xanthine/uracil/vitamin C permease family permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSKLDAFFKFKENNTDVKTEIIAGITIFLAMAYILIVNPAMLSETGMDIQGVFIATALSAAIATILMGYIANYPYALAAG
MGLNAFFTYTVVLTMGYSWEYALLAIFVSGIIFLVISLTSLREKLFYSIPDSLRFGISIGIGLFILALGLSNLGILSYSS
QVINIGDANWATQLIGLGSASTIFTLGNLLALICFVIIMVLMKKNVKGNILIGIIATYIIGVVLELAGCPVLPDQSLIPT
AIINSNLGGSLGNVAFKFGEASGVFTGVRAFIDFIIIAVTFLVISLFDTMGTLTALTTKVDGYDENGKLPRLKKVLSVDA
LGPIIGSVLGTSPVVTYIESSTGIMEGGRTGLTAIVVGILFLLAIPFAPIFTIIPTFAVAPALVVVGILMCGLYKNLDTG
NLSDLIPALAAIIVTPLTQSITTGIIAGVFAFVIVKVLFGKAKEISKAMWILFALLFIYMVLEFIM

Sequences:

>Translated_466_residues
MSKLDAFFKFKENNTDVKTEIIAGITIFLAMAYILIVNPAMLSETGMDIQGVFIATALSAAIATILMGYIANYPYALAAG
MGLNAFFTYTVVLTMGYSWEYALLAIFVSGIIFLVISLTSLREKLFYSIPDSLRFGISIGIGLFILALGLSNLGILSYSS
QVINIGDANWATQLIGLGSASTIFTLGNLLALICFVIIMVLMKKNVKGNILIGIIATYIIGVVLELAGCPVLPDQSLIPT
AIINSNLGGSLGNVAFKFGEASGVFTGVRAFIDFIIIAVTFLVISLFDTMGTLTALTTKVDGYDENGKLPRLKKVLSVDA
LGPIIGSVLGTSPVVTYIESSTGIMEGGRTGLTAIVVGILFLLAIPFAPIFTIIPTFAVAPALVVVGILMCGLYKNLDTG
NLSDLIPALAAIIVTPLTQSITTGIIAGVFAFVIVKVLFGKAKEISKAMWILFALLFIYMVLEFIM
>Mature_465_residues
SKLDAFFKFKENNTDVKTEIIAGITIFLAMAYILIVNPAMLSETGMDIQGVFIATALSAAIATILMGYIANYPYALAAGM
GLNAFFTYTVVLTMGYSWEYALLAIFVSGIIFLVISLTSLREKLFYSIPDSLRFGISIGIGLFILALGLSNLGILSYSSQ
VINIGDANWATQLIGLGSASTIFTLGNLLALICFVIIMVLMKKNVKGNILIGIIATYIIGVVLELAGCPVLPDQSLIPTA
IINSNLGGSLGNVAFKFGEASGVFTGVRAFIDFIIIAVTFLVISLFDTMGTLTALTTKVDGYDENGKLPRLKKVLSVDAL
GPIIGSVLGTSPVVTYIESSTGIMEGGRTGLTAIVVGILFLLAIPFAPIFTIIPTFAVAPALVVVGILMCGLYKNLDTGN
LSDLIPALAAIIVTPLTQSITTGIIAGVFAFVIVKVLFGKAKEISKAMWILFALLFIYMVLEFIM

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=463, Percent_Identity=36.5010799136069, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1790150, Length=457, Percent_Identity=38.2932166301969, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1790499, Length=453, Percent_Identity=32.2295805739514, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI48994909, Length=448, Percent_Identity=33.4821428571429, Blast_Score=178, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49470; Mature: 49339

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLDAFFKFKENNTDVKTEIIAGITIFLAMAYILIVNPAMLSETGMDIQGVFIATALSA
CCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHH
AIATILMGYIANYPYALAAGMGLNAFFTYTVVLTMGYSWEYALLAIFVSGIIFLVISLTS
HHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LREKLFYSIPDSLRFGISIGIGLFILALGLSNLGILSYSSQVINIGDANWATQLIGLGSA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCHHHHHHHHCCCH
STIFTLGNLLALICFVIIMVLMKKNVKGNILIGIIATYIIGVVLELAGCPVLPDQSLIPT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AIINSNLGGSLGNVAFKFGEASGVFTGVRAFIDFIIIAVTFLVISLFDTMGTLTALTTKV
HHHCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGYDENGKLPRLKKVLSVDALGPIIGSVLGTSPVVTYIESSTGIMEGGRTGLTAIVVGIL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FLLAIPFAPIFTIIPTFAVAPALVVVGILMCGLYKNLDTGNLSDLIPALAAIIVTPLTQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ITTGIIAGVFAFVIVKVLFGKAKEISKAMWILFALLFIYMVLEFIM
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SKLDAFFKFKENNTDVKTEIIAGITIFLAMAYILIVNPAMLSETGMDIQGVFIATALSA
CCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHH
AIATILMGYIANYPYALAAGMGLNAFFTYTVVLTMGYSWEYALLAIFVSGIIFLVISLTS
HHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LREKLFYSIPDSLRFGISIGIGLFILALGLSNLGILSYSSQVINIGDANWATQLIGLGSA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCHHHHHHHHCCCH
STIFTLGNLLALICFVIIMVLMKKNVKGNILIGIIATYIIGVVLELAGCPVLPDQSLIPT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AIINSNLGGSLGNVAFKFGEASGVFTGVRAFIDFIIIAVTFLVISLFDTMGTLTALTTKV
HHHCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGYDENGKLPRLKKVLSVDALGPIIGSVLGTSPVVTYIESSTGIMEGGRTGLTAIVVGIL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FLLAIPFAPIFTIIPTFAVAPALVVVGILMCGLYKNLDTGNLSDLIPALAAIIVTPLTQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ITTGIIAGVFAFVIVKVLFGKAKEISKAMWILFALLFIYMVLEFIM
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]