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The map label for this gene is moaA [H]

Identifier: 148643466

GI number: 148643466

Start: 1432387

End: 1433316

Strand: Reverse

Name: moaA [H]

Synonym: Msm_1406

Alternate gene names: 148643466

Gene position: 1433316-1432387 (Counterclockwise)

Preceding gene: 148643467

Following gene: 148643458

Centisome position: 77.34

GC content: 30.54

Gene sequence:

>930_bases
ATGAGTATAGAAGCTATCAAAGACAAATATGAACGACCAATACTTTCATTAAGAATTACAATAACAAACAAATGTAATGA
AAATTGTTTATACTGCCACCATGATGGGATGGATGATTCTCAAGAGGAAATGAATGCAGATGAAATTTACAGAATCTGTG
AAATAGCCAAAAATATTGGTGTTAGAAAAATAAGGATTTCTGGTGGAGAGCCTTTAATAAGAAAAGACATCGTTGAAATT
GTAAGTAAAATAGCCAGCCTTGATTTTGATGACATATCCATTACTTCAAATGGAACCTTACTTGGAAAATATGCAAAAGA
TCTAAAAGAAGCTGGATTAAATAGGGTAAATATCAGTTTAGATACTTTAAATCCTGAAACTTACAAAAAAGTTACCACTA
AAAATCTGCTTGAATCATCAAAAAACGGAATTCTGAAAGCTGTTGAAGTTGGCCTTTATCCCGTTAAAATCAATATGGTT
TTAATGAAAGGAATAAATGAAAACGAAGTGGATGATATGTTTGAATTTTGTAAAGAACATGGCATCATACTTCAGCTTAT
TGAATTAATGGACAGTGAAAACTGTGATGATGAAAAATTCAGCAGAGATTATCATTATAATTTAGATCCCATCAATGAAA
AGTTGCTTTCCATATGTGATGAAGTCAAAACACGTGAATTTATGCAAAACCGTAAAAAATACTTCATAGACGGAGGAGAA
ATTGAAGTAGTAAAACCTATTGAAAACAGCGACTTTTGTGCAAATTGTACTAGATTAAGAATAACTCCTGACGGAAAAAT
AAAGCCATGCTTACTTAGAAATGACAATCTGGTAGAATTAATATCACATATAAGAAATAATGAATCAGATTCTCAACTAA
AAGAAGTTTTCATTAAAGGCATTGACAAAAGAGAGCCTTATAACAATTAA

Upstream 100 bases:

>100_bases
CTAAAGGAAACAATTTACGGTATGATTAAATCATTGAAACTTGGAGAACTAGACATCAATGAAATCGAAACTATTAATAT
AACTGTTAAAAAATGATTTT

Downstream 100 bases:

>100_bases
AAGCTATTTTTAAACAGAAGATTTTTATCTTCTAAAATTAATTTTTTTTAAAAAAAAGAAGTAAATAGAGTAAAAACTCT
ATTTCCAGTTATCTTTTGGT

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSIEAIKDKYERPILSLRITITNKCNENCLYCHHDGMDDSQEEMNADEIYRICEIAKNIGVRKIRISGGEPLIRKDIVEI
VSKIASLDFDDISITSNGTLLGKYAKDLKEAGLNRVNISLDTLNPETYKKVTTKNLLESSKNGILKAVEVGLYPVKINMV
LMKGINENEVDDMFEFCKEHGIILQLIELMDSENCDDEKFSRDYHYNLDPINEKLLSICDEVKTREFMQNRKKYFIDGGE
IEVVKPIENSDFCANCTRLRITPDGKIKPCLLRNDNLVELISHIRNNESDSQLKEVFIKGIDKREPYNN

Sequences:

>Translated_309_residues
MSIEAIKDKYERPILSLRITITNKCNENCLYCHHDGMDDSQEEMNADEIYRICEIAKNIGVRKIRISGGEPLIRKDIVEI
VSKIASLDFDDISITSNGTLLGKYAKDLKEAGLNRVNISLDTLNPETYKKVTTKNLLESSKNGILKAVEVGLYPVKINMV
LMKGINENEVDDMFEFCKEHGIILQLIELMDSENCDDEKFSRDYHYNLDPINEKLLSICDEVKTREFMQNRKKYFIDGGE
IEVVKPIENSDFCANCTRLRITPDGKIKPCLLRNDNLVELISHIRNNESDSQLKEVFIKGIDKREPYNN
>Mature_308_residues
SIEAIKDKYERPILSLRITITNKCNENCLYCHHDGMDDSQEEMNADEIYRICEIAKNIGVRKIRISGGEPLIRKDIVEIV
SKIASLDFDDISITSNGTLLGKYAKDLKEAGLNRVNISLDTLNPETYKKVTTKNLLESSKNGILKAVEVGLYPVKINMVL
MKGINENEVDDMFEFCKEHGIILQLIELMDSENCDDEKFSRDYHYNLDPINEKLLSICDEVKTREFMQNRKKYFIDGGEI
EVVKPIENSDFCANCTRLRITPDGKIKPCLLRNDNLVELISHIRNNESDSQLKEVFIKGIDKREPYNN

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=308, Percent_Identity=32.4675324675325, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI22027536, Length=308, Percent_Identity=32.4675324675325, Blast_Score=155, Evalue=5e-38,
Organism=Escherichia coli, GI1786999, Length=275, Percent_Identity=30.9090909090909, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32566331, Length=312, Percent_Identity=34.9358974358974, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI32566329, Length=312, Percent_Identity=34.9358974358974, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17561210, Length=312, Percent_Identity=33.974358974359, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574490, Length=291, Percent_Identity=34.7079037800687, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI28574488, Length=291, Percent_Identity=34.7079037800687, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013485
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 35478; Mature: 35347

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEAIKDKYERPILSLRITITNKCNENCLYCHHDGMDDSQEEMNADEIYRICEIAKNIG
CCHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHCC
VRKIRISGGEPLIRKDIVEIVSKIASLDFDDISITSNGTLLGKYAKDLKEAGLNRVNISL
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEE
DTLNPETYKKVTTKNLLESSKNGILKAVEVGLYPVKINMVLMKGINENEVDDMFEFCKEH
ECCCHHHHHHHHHHHHHHHHCCCCEEEHHHCEEEEEEEEEEECCCCCCHHHHHHHHHHHC
GIILQLIELMDSENCDDEKFSRDYHYNLDPINEKLLSICDEVKTREFMQNRKKYFIDGGE
CHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
IEVVKPIENSDFCANCTRLRITPDGKIKPCLLRNDNLVELISHIRNNESDSQLKEVFIKG
EEEECCCCCCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHC
IDKREPYNN
CCCCCCCCC
>Mature Secondary Structure 
SIEAIKDKYERPILSLRITITNKCNENCLYCHHDGMDDSQEEMNADEIYRICEIAKNIG
CHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHCC
VRKIRISGGEPLIRKDIVEIVSKIASLDFDDISITSNGTLLGKYAKDLKEAGLNRVNISL
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEE
DTLNPETYKKVTTKNLLESSKNGILKAVEVGLYPVKINMVLMKGINENEVDDMFEFCKEH
ECCCHHHHHHHHHHHHHHHHCCCCEEEHHHCEEEEEEEEEEECCCCCCHHHHHHHHHHHC
GIILQLIELMDSENCDDEKFSRDYHYNLDPINEKLLSICDEVKTREFMQNRKKYFIDGGE
CHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
IEVVKPIENSDFCANCTRLRITPDGKIKPCLLRNDNLVELISHIRNNESDSQLKEVFIKG
EEEECCCCCCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHC
IDKREPYNN
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]