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The map label for this gene is adh [H]

Identifier: 148643440

GI number: 148643440

Start: 1397599

End: 1398165

Strand: Reverse

Name: adh [H]

Synonym: Msm_1380

Alternate gene names: 148643440

Gene position: 1398165-1397599 (Counterclockwise)

Preceding gene: 148643441

Following gene: 148643439

Centisome position: 75.45

GC content: 41.09

Gene sequence:

>567_bases
ATGGTCTTAGGTCATGAAGCAGTCGGTATTGTTGAAGAAGTTGGCAGCTTAGTGAAAAATATCAAAGTAGGAGACAAAGT
AATTGTACCTGCTATTACTCCGGACTGGGATGATGAAGCTGCTCAAAGAGGTTATCCTTCACAAACTACAGAACCATTAG
GCGGATGGAAATTTTCAAATTTCAAAGACGGTGCTTTTGGAGAAAGATTCCATGTCAATTTAGCTGATGCTAACTTAGCC
CTAATGCCTGAAGGATTAACTGATGAAGCTGCAGTAATGCTTGTAGATATGTGGTCTACCGGTATGATGGGATCTGAAAA
TGCAAATATACCATTAGGAGGAAGCGTATTAGTAATTGGAATCGGTGCTGTAGGGCTTTCAGCAATTGCAGGTGCTGCCC
TTTTAGGTGCTGCAGATATTTATGCTGCAGGAACCCGTCCCGTTTCAGTGAAAGTTGCAAAAGAGTACGGAGCTACAGAA
ATTATCAATTACAGGGAAGCTCCAATTGATGAACAAGTTAGAGAAGCTACAAATGGAGCAGGTGTTGACTCTGTAATTTT
ATTGTAG

Upstream 100 bases:

>100_bases
GTGGACCATTAGACGCAATTGTAAGACCAACATGTGTCTCTCTCCTTGTACTTCAGATATACATACAGTATGGGAAGGAG
CTATCGGAGATAGAAAAGAC

Downstream 100 bases:

>100_bases
GAGGAAACTTAACAAACACTTGGAAAGAAGCTGTAGCTAGTACAAAAGCCGGAGGAACAATATCAAATGTAAACTACTTA
AGTGGAGCAGATGATGTTTT

Product: NADP-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MVLGHEAVGIVEEVGSLVKNIKVGDKVIVPAITPDWDDEAAQRGYPSQTTEPLGGWKFSNFKDGAFGERFHVNLADANLA
LMPEGLTDEAAVMLVDMWSTGMMGSENANIPLGGSVLVIGIGAVGLSAIAGAALLGAADIYAAGTRPVSVKVAKEYGATE
IINYREAPIDEQVREATNGAGVDSVILL

Sequences:

>Translated_188_residues
MVLGHEAVGIVEEVGSLVKNIKVGDKVIVPAITPDWDDEAAQRGYPSQTTEPLGGWKFSNFKDGAFGERFHVNLADANLA
LMPEGLTDEAAVMLVDMWSTGMMGSENANIPLGGSVLVIGIGAVGLSAIAGAALLGAADIYAAGTRPVSVKVAKEYGATE
IINYREAPIDEQVREATNGAGVDSVILL
>Mature_188_residues
MVLGHEAVGIVEEVGSLVKNIKVGDKVIVPAITPDWDDEAAQRGYPSQTTEPLGGWKFSNFKDGAFGERFHVNLADANLA
LMPEGLTDEAAVMLVDMWSTGMMGSENANIPLGGSVLVIGIGAVGLSAIAGAALLGAADIYAAGTRPVSVKVAKEYGATE
IINYREAPIDEQVREATNGAGVDSVILL

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=205, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI156627571, Length=169, Percent_Identity=32.5443786982249, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786825, Length=207, Percent_Identity=31.4009661835749, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319955, Length=172, Percent_Identity=31.9767441860465, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=172, Percent_Identity=31.9767441860465, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320033, Length=209, Percent_Identity=32.0574162679426, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737897, Length=184, Percent_Identity=28.804347826087, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137530, Length=163, Percent_Identity=31.2883435582822, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.2 [H]

Molecular weight: Translated: 19538; Mature: 19538

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLGHEAVGIVEEVGSLVKNIKVGDKVIVPAITPDWDDEAAQRGYPSQTTEPLGGWKFSN
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
FKDGAFGERFHVNLADANLALMPEGLTDEAAVMLVDMWSTGMMGSENANIPLGGSVLVIG
CCCCCCCCEEEEEEECCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEE
IGAVGLSAIAGAALLGAADIYAAGTRPVSVKVAKEYGATEIINYREAPIDEQVREATNGA
ECHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCEEECCCCCCCHHHHHHHCCCC
GVDSVILL
CCEEEEEC
>Mature Secondary Structure
MVLGHEAVGIVEEVGSLVKNIKVGDKVIVPAITPDWDDEAAQRGYPSQTTEPLGGWKFSN
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
FKDGAFGERFHVNLADANLALMPEGLTDEAAVMLVDMWSTGMMGSENANIPLGGSVLVIG
CCCCCCCCEEEEEEECCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEE
IGAVGLSAIAGAALLGAADIYAAGTRPVSVKVAKEYGATEIINYREAPIDEQVREATNGA
ECHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCEEECCCCCCCHHHHHHHCCCC
GVDSVILL
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2790012; 9836873 [H]