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The map label for this gene is cobI [H]

Identifier: 148643411

GI number: 148643411

Start: 1375366

End: 1376070

Strand: Reverse

Name: cobI [H]

Synonym: Msm_1351

Alternate gene names: 148643411

Gene position: 1376070-1375366 (Counterclockwise)

Preceding gene: 148643413

Following gene: 148643409

Centisome position: 74.26

GC content: 30.92

Gene sequence:

>705_bases
ATGGCGAAAAAAGGAAAGTTAATTGGAATTGGTGTTGGACCTGGAGATACAGAATTACTTACTTTAAAAGCAGCTAAAGT
TTTAGAAAGTGTTCCGGTAATATTTTCACCAAAATCCGCAAAAGAAAAGAAAAGTATAGCATTGTCAATTGTAACACCAA
TTTTAGAAAAAAGAAAAGATTATAAAAGATTAATGGTTGTAGAACCTTTATTCCCAATGATTGAAGATCAGCAAGAGCTT
GAAAAATATTGGAATAGTGCTGCAGAATTAATAGCTAATTATTTAGACAGCGGAAGAGATGTAGCTTTTATAACTCTTGG
AGATCCTTCAATATTTAGTACATATTCATATACTCAAAAGAAACTGGCCAATAGATATGAAATAGAAACAATACCCGGGA
TTACTTCATTTACTGCCTGTGCAGCTGCTAAAAATGAACCTTTAGTTGAAAAAAATGACATATTAACTATTGTTCCAAAA
ATAGATGGCAGATTGGACAATTTCCTGGAACATAGTGATTCAATCGTTTTAATGAAAGCTTCCAGAAATACAAAAGAATT
GGAATCTGCTATTGATGAAAAAAACAGACCTAAAGAAGTATTTTCAGTACAAAATTGTACCCAAGAAAATGAAAAAATAG
TGGAAGGTTTTTCAACTGAAAAACCATACCTTACAACAACCATAATTAAATTTACAGATGACTAA

Upstream 100 bases:

>100_bases
TTAGACATCAAACAATATATTAGTTACAATACTATAAATAAATTATAGAAGTGCATATGAAAACTAATATTCACAAAAAT
TAAATCATAAAGATGATAAT

Downstream 100 bases:

>100_bases
AATTATTTGCGTTTAAAAGGCTCAATTTCAAAAACACAGTTTTCATCGCCCATTGAACAGCATTGAATTTCAATTACACG
AACAGGCAATCCGAAAAATT

Product: precorrin-2 C20-methyltransferase, CbiL

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAKKGKLIGIGVGPGDTELLTLKAAKVLESVPVIFSPKSAKEKKSIALSIVTPILEKRKDYKRLMVVEPLFPMIEDQQEL
EKYWNSAAELIANYLDSGRDVAFITLGDPSIFSTYSYTQKKLANRYEIETIPGITSFTACAAAKNEPLVEKNDILTIVPK
IDGRLDNFLEHSDSIVLMKASRNTKELESAIDEKNRPKEVFSVQNCTQENEKIVEGFSTEKPYLTTTIIKFTDD

Sequences:

>Translated_234_residues
MAKKGKLIGIGVGPGDTELLTLKAAKVLESVPVIFSPKSAKEKKSIALSIVTPILEKRKDYKRLMVVEPLFPMIEDQQEL
EKYWNSAAELIANYLDSGRDVAFITLGDPSIFSTYSYTQKKLANRYEIETIPGITSFTACAAAKNEPLVEKNDILTIVPK
IDGRLDNFLEHSDSIVLMKASRNTKELESAIDEKNRPKEVFSVQNCTQENEKIVEGFSTEKPYLTTTIIKFTDD
>Mature_233_residues
AKKGKLIGIGVGPGDTELLTLKAAKVLESVPVIFSPKSAKEKKSIALSIVTPILEKRKDYKRLMVVEPLFPMIEDQQELE
KYWNSAAELIANYLDSGRDVAFITLGDPSIFSTYSYTQKKLANRYEIETIPGITSFTACAAAKNEPLVEKNDILTIVPKI
DGRLDNFLEHSDSIVLMKASRNTKELESAIDEKNRPKEVFSVQNCTQENEKIVEGFSTEKPYLTTTIIKFTDD

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26168; Mature: 26037

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKGKLIGIGVGPGDTELLTLKAAKVLESVPVIFSPKSAKEKKSIALSIVTPILEKRKD
CCCCCCEEEEECCCCCCEEEEHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
YKRLMVVEPLFPMIEDQQELEKYWNSAAELIANYLDSGRDVAFITLGDPSIFSTYSYTQK
HHHEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
KLANRYEIETIPGITSFTACAAAKNEPLVEKNDILTIVPKIDGRLDNFLEHSDSIVLMKA
HHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEC
SRNTKELESAIDEKNRPKEVFSVQNCTQENEKIVEGFSTEKPYLTTTIIKFTDD
CCCHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
AKKGKLIGIGVGPGDTELLTLKAAKVLESVPVIFSPKSAKEKKSIALSIVTPILEKRKD
CCCCCEEEEECCCCCCEEEEHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
YKRLMVVEPLFPMIEDQQELEKYWNSAAELIANYLDSGRDVAFITLGDPSIFSTYSYTQK
HHHEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
KLANRYEIETIPGITSFTACAAAKNEPLVEKNDILTIVPKIDGRLDNFLEHSDSIVLMKA
HHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEC
SRNTKELESAIDEKNRPKEVFSVQNCTQENEKIVEGFSTEKPYLTTTIIKFTDD
CCCHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]