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The map label for this gene is ribH

Identifier: 148643356

GI number: 148643356

Start: 1302579

End: 1302995

Strand: Reverse

Name: ribH

Synonym: Msm_1296

Alternate gene names: 148643356

Gene position: 1302995-1302579 (Counterclockwise)

Preceding gene: 148643357

Following gene: 148643355

Centisome position: 70.31

GC content: 36.69

Gene sequence:

>417_bases
ATGGCAAAATATAATATAGGCGCAGTAGTCGCTGAATTTAATTATGACATAACTCAGATGATGTTAGGTTTAGCTAAAGA
AGAAGCTAAATCCAGAGACTGTGAAATTACACAGGTAGTAACCGTTCCTGGAGTATTTGATATGGCATTAGCTATTAAAA
AATTACTTGAAAAAGATGAAATTGATGCAGTAATCACTCTTGGAGCAGTAATTGAAGGAGCTACAGACCACGACCAAATT
GTAGCACAGCATGCATCCCGTAAAATAGCTGACTTATCCTTAGAATACGAAAAACCAGTAGCTTTAGGAATCAGCGGACC
AGGTATGACAAGATTAGATGCACACAAACGTGTAGATTACGGTAAAAGAGCTGTTGAAGCAGCTATTAAAATGTGCGATA
GATTAAACGAAATTTAG

Upstream 100 bases:

>100_bases
CGATAAAAAAAGAGCAGCTGCACTTTTTATCATCTTAATTATGGTATTAAGTGGTGTTGCAAGTTTTATGTTAATGGTTA
TCTAATTGGAGGACTTAAAA

Downstream 100 bases:

>100_bases
ATGATTACATGGAAATTCTAAAACCTGATCAGTTAAAAGAAAAATTTAATGACCCCTGGATTGCACCCTACCAAAAAGTA
TTGACAATGGTAGATGGAGA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MAKYNIGAVVAEFNYDITQMMLGLAKEEAKSRDCEITQVVTVPGVFDMALAIKKLLEKDEIDAVITLGAVIEGATDHDQI
VAQHASRKIADLSLEYEKPVALGISGPGMTRLDAHKRVDYGKRAVEAAIKMCDRLNEI

Sequences:

>Translated_138_residues
MAKYNIGAVVAEFNYDITQMMLGLAKEEAKSRDCEITQVVTVPGVFDMALAIKKLLEKDEIDAVITLGAVIEGATDHDQI
VAQHASRKIADLSLEYEKPVALGISGPGMTRLDAHKRVDYGKRAVEAAIKMCDRLNEI
>Mature_137_residues
AKYNIGAVVAEFNYDITQMMLGLAKEEAKSRDCEITQVVTVPGVFDMALAIKKLLEKDEIDAVITLGAVIEGATDHDQIV
AQHASRKIADLSLEYEKPVALGISGPGMTRLDAHKRVDYGKRAVEAAIKMCDRLNEI

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_METS3 (A5UMS3)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273869.1
- ProteinModelPortal:   A5UMS3
- SMR:   A5UMS3
- STRING:   A5UMS3
- GeneID:   5216590
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_1296
- eggNOG:   arNOG09975
- HOGENOM:   HBG311126
- OMA:   GFVVAEF
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 15090; Mature: 14958

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYNIGAVVAEFNYDITQMMLGLAKEEAKSRDCEITQVVTVPGVFDMALAIKKLLEKDE
CCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
IDAVITLGAVIEGATDHDQIVAQHASRKIADLSLEYEKPVALGISGPGMTRLDAHKRVDY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEECCCCCEEEEECCCCCCHHHHHHHHHH
GKRAVEAAIKMCDRLNEI
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKYNIGAVVAEFNYDITQMMLGLAKEEAKSRDCEITQVVTVPGVFDMALAIKKLLEKDE
CCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
IDAVITLGAVIEGATDHDQIVAQHASRKIADLSLEYEKPVALGISGPGMTRLDAHKRVDY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEECCCCCEEEEECCCCCCHHHHHHHHHH
GKRAVEAAIKMCDRLNEI
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA